Gene Information

Name : Phep_2582 (Phep_2582)
Accession : YP_003092848.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3005382 - 3006110 bp
Length : 729 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAGTACTTGGCATTATACCGGCACGTTATGCCTCTACCCGTTTTCCTGGTAAGCCTTTAATAGAAATTCAGGGCAA
AAGCATGATCCAAAGGGTTTATGAACAAGCTTTAAAAGCCATAAGTTTAACCAAGGTAGTGGTGGCTACAGATGACGAAC
GCATTGCAGAGGCCATAAATAACTTTGGTGCTGAATTTGTAATGACCAGAGATGATCATCAGAGTGGTACAGACCGTTGT
GCAGAGGTATCACAGCACTTTCCTGATTTTGATATTGTAATCAATATACAGGGAGATGAACCTTTCATCAATCCCAAACA
AATAGACCTGCTGGTATCCTGTTTTGAGCATGGCAATGTAAAACTGGCAACATTGATTAAAGAAATCCATACGGAAGAGG
AACTACTTAATACCAATATTCCAAAGGTTGTGATCAACAGCAGACAGGAAGCTATATATTTTAGCAGACATACCATTCCT
TACATCAGAAATGCTGAAAAAAACAAATGGCTTGATGTGCATCAGTTTTATAAACACATTGGAATTTACGGTTATACCAC
CCCTACCTTGCTTGAAATCACCAGGCTCCAACCTTCTTCACTTGAAATGGCTGAAAGCCTGGAACAATTGAGATGGGTAG
AAAACGGTTATACCATCCAGACCAGGATAACAGCCATAGAAACAATTGCAATAGATACCCCTGAAGACCTGGATAAAATT
GTGGGATAA

Protein sequence :
MKVLGIIPARYASTRFPGKPLIEIQGKSMIQRVYEQALKAISLTKVVVATDDERIAEAINNFGAEFVMTRDDHQSGTDRC
AEVSQHFPDFDIVINIQGDEPFINPKQIDLLVSCFEHGNVKLATLIKEIHTEEELLNTNIPKVVINSRQEAIYFSRHTIP
YIRNAEKNKWLDVHQFYKHIGIYGYTTPTLLEITRLQPSSLEMAESLEQLRWVENGYTIQTRITAIETIAIDTPEDLDKI
VG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-43 47
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-42 47
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 7e-43 47