Gene Information

Name : lysS (Phep_1559)
Accession : YP_003091834.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1843484 - 1845205 bp
Length : 1722 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGTACAGGACTATCAGAATTAGAAGTATTGCGCCGTAATTCGCTAACACAATTACGTGAACTGGGTATCAATCCCTA
TCCTGCCGAAGCATTTGAGATCAATGCCCATGCAGCAGATATTTTAGCGAATTACGAACGGGATAAAACTGCTTATAAGA
ACATCAGCATGGCGGGCCGCATCATGAGCCGCAGAATTATGGGAAGTGCTTCTTTTGTGGAATTACAGGACTCAACCGGA
AGAATACAGGTTTATCTGAAAAGAGATGACCTGTGTCCGGATGAAGACAAAACTTTATACAATACCGTATTTAAGAAATT
GCTGGACCTTGGTGATTTTATTGGTATAAAAGGTTATGTTTTTACCACACAAACGGGTGAGATCTCTGTTCATGTAACAG
CACTTACTTTGCTTTCCAAGTCTTTAAAACCATTGCCTATTGTTAAACGTGACGAGGAAGGAAATATTTATGATGGTTTT
ACTGATCCTGAAATGCGTTACAGGCAGCGTTATGTAGACCTTACGGTAAATCCGGGCTTTAAACAGATTTTTATCAACCG
TTCCAAGGTGATCAATACCATGCGTGGATATTTTGATAATCAGGGCTGGATGGAAGTGGAAACACCTATTCTGCAACCCA
TTCATGGTGGTGCTGCAGCCCGTCCATTTGCTACACACCACAATACGCTGGATATGCCATTGTACCTGCGTATTGCCAAT
GAACTTTACCTGAAAAGACTGATTGTAGCAGGTTTTGACGGCGTTTATGAGTTTGGTAAAATGTTCAGAAACGAAGGGAT
GGACCGTACCCATAATCCTGAATTTACCTCTATGGAGATTTATGTAGCTTATAAAGACTACATCTGGATGATGGCCATGG
TAGAAGAATGCCTGGAGAAAGTAGCTCTGGCGATCCATGGAAAACCTGTAGTAAAAGTTGGGGATTATGAGATCAACTTT
GAAGGCCCATACGAAAAACTGACCATGTACGAGTCTATCCAGAAATATACAGGTATAGATGTTTCAGTTATGACAGAAGA
AGAGATCAAAACGGTTTGCAAAAGCCTGGGCATAGAAATTGATAATTCTATGGGCAGGGGCAAGCTGATTGATGAACTGT
TCAGCGAAAAAGTAGAGGCGAACCTGATCCAGCCGACTTACATTACCGATTATCCGTTGGAAATGACACCTCTGGCTAAA
AAACACAGAAGCAAGGAAGGACTGGTAGAACGTTTTGAATTATTTGTGATGGGTAAAGAAATTGCCAATGCTTACTCTGA
GCTGAATGACCCTATTGATCAGCGGGAACGCTTTGAAGACCAGTTAAAACTTGCTGCAAGAGGTGATGATGAGGCGATGG
CGATGGACGATGATTTTATCCGTGCCCTGGAATATGGCATGCCACCTACATCGGGTCTGGGTATTGGTATAGATCGTCTG
GTAATGCTGATGACCGATCAATCGACCATACAGGAAGTATTGTTTTTTCCGCAGATGAGGCCGGAAAAGAAAGTCAAAAT
AACAACTGATGAGGATTTTGTAAATGCCGGTGTACCTGCTGAATGGGTACAGGCAGTCCGCAAAATGGGCATCAACACCA
TAGAGGAATTAAAAGCAGCAAATCCAAATAAGGTTTTTAACGATCTGGGGGGTATGCGTAAAAAACTTAAATTGGAGCTG
GCCATGCCTTCAAAAGAAGAGGTTACAGCCTGGTTTGCTTAA

Protein sequence :
MSTGLSELEVLRRNSLTQLRELGINPYPAEAFEINAHAADILANYERDKTAYKNISMAGRIMSRRIMGSASFVELQDSTG
RIQVYLKRDDLCPDEDKTLYNTVFKKLLDLGDFIGIKGYVFTTQTGEISVHVTALTLLSKSLKPLPIVKRDEEGNIYDGF
TDPEMRYRQRYVDLTVNPGFKQIFINRSKVINTMRGYFDNQGWMEVETPILQPIHGGAAARPFATHHNTLDMPLYLRIAN
ELYLKRLIVAGFDGVYEFGKMFRNEGMDRTHNPEFTSMEIYVAYKDYIWMMAMVEECLEKVALAIHGKPVVKVGDYEINF
EGPYEKLTMYESIQKYTGIDVSVMTEEEIKTVCKSLGIEIDNSMGRGKLIDELFSEKVEANLIQPTYITDYPLEMTPLAK
KHRSKEGLVERFELFVMGKEIANAYSELNDPIDQRERFEDQLKLAARGDDEAMAMDDDFIRALEYGMPPTSGLGIGIDRL
VMLMTDQSTIQEVLFFPQMRPEKKVKITTDEDFVNAGVPAEWVQAVRKMGINTIEELKAANPNKVFNDLGGMRKKLKLEL
AMPSKEEVTAWFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-95 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_003091834.1 lysyl-tRNA synthetase VFG1668 Protein 9e-96 45