Gene Information

Name : Phep_1456 (Phep_1456)
Accession : YP_003091732.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1729292 - 1731886 bp
Length : 2595 bp
Strand : -
Note : PFAM: ATPase family associated with various cellular activities (AAA); ATPase family associated with various cellular activities (AAA); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: ATP-dependent chaperone ClpB

DNA sequence :
ATGAATTTCAACAACTTTACCATAAAAGCTCAGGAAGCAATTCAACAGGCTTCTGAAATAGCCACTGGCAATCAGCAGCA
GGCTATTGAAACAGCGCACATCCTGAAGGGTTTGCTTACTGTTGACGAAAATGTAGTTTCTTATGTACTAAAGAAACTAA
ATGTAAACCTAAATGTGCTGAACCAGCAACTGGACGCACAGATTGAAAAATTTCCGAAAGTTACAGGCAGCAGCCCTTAC
CTAACCTCGGGCAGTAATTCCGCTTTGCAAAAAGCAAATTCTTACCTGAAAGAGTTTAAAGATGAATTTGTTTCTGTAGA
GCATGTATTACTTGGCCTGCTTTCGGTAAATGACGATACCGCAAAACACCTGAAAGATCAGGGGGTTACTGAAAAAGACC
TTAAAAAAGCGATTATCGCTTTGCGGGGCGACAACCATGTAACGGGACAAAATGCCGAGGCAACTTACAATGCCCTTAAT
AAATATGCAAGAAATTTAAATGAATATGCAGAATCCGGAAAACTGGACCCTGTTATTGGCCGGGATGAAGAGATCAGACG
CGTAATCCAGATCTTATCCAGACGTACAAAAAACAATCCGATCCTGATCGGTGAGCCTGGTGTAGGTAAAACAGCCATTG
CCGAGGGTATCGCTTTCAGGATCATCAAAGGTGATGTGCCTACCAACCTGAAAACTAAAACAGTTTATTCGCTGGATATG
GGCGCCCTGATAGCCGGTGCAAAGTATAAAGGAGAATTTGAGGAAAGACTGAAAGCAGTAGTAAAAGAGGTTACACAGAG
TGATGGCGATATCATTTTGTTTATTGATGAGATCCATACTCTGGTTGGTGCCGGTGGTGGCGAAGGTGCAATGGATGCGG
CAAACATTTTAAAACCTGCCCTTGCCCGCGGTGAGCTGCGTGCCATTGGTGCAACAACTTTGGATGAATACCAGAAATAC
CTGGAAAAGGATAAAGCCCTGGAGCGCCGTTTCCAAAAGGTAATGGTAGATGAGCCGGATACTCAGGATGCCATCTCTAT
TTTGCGTGGGTTAAAAGAACGCTATGAGACCCACCATAAGGTGCGGATTAAAGATGAGGCCATTATTGCCGCTGTAGAAA
TGTCGCAACGGTATATTGCCGACCGGTTCTTACCGGATAAAGCCATCGATCTGATGGATGAGGCAGCGTCTAAACTGCGT
CTGGAAATGGATAGCGTGCCGGAGAAAGTGGATGAACTGAACCGTAAAATCATGCAGCTGGAAATTGAACGCGAAGCAAT
CAAGCGGGAAAATGATACCAGGAAGGTGAAATCACTGGCTGAAGAAATTGCCAACCTTTCGGCTGAAAGGGATGAAATTA
AAGCCAAATGGCAGGGCGAGAAAGACCTGGTAGATAACATCAACAATGAGATTGAACAGATCGAAAACTATAAGCTGGAA
GCCGATCAGGCTGAACGCGCAGGCGATTACGGAAAGGTTGCCGAAATCCGCTACGGCAAAATAAAAGAGGCACAGGACAA
AGTTGAAAAACTAAAAGTACAGCTGGAAAGTCAGCAAACCGAAGGCCGCATGCTGAAAGAAGAAGTTACTGCTGACGACA
TTGCAGGTGTGGTAGGCAGGTGGACCGGTATTCCGGTAACCAAACTGGTTTCCAGTGAGCGTGAAAAGTTGCTGAATCTG
GAAACGGAACTGCACAAACGTGTAGCAGGACAGCATGAAGCTATTGAAGCGATATCTGATGCCATCCGCCGCTCCCGTGC
CGGCCTGCAGGATAAAAGAAAACCCATTGGTTCCTTCATATTCCTGGGCACTACAGGTGTGGGTAAAACCGAGCTGGCAA
AGGCATTGGCAGAATTCCTGTTCAACGACGAAAATGCTATGACCCGTATTGACATGAGCGAATATCAGGAACGCCATGCA
GTTTCACGCTTAATTGGTGCGCCTCCAGGCTATGTGGGTTATGATGAAGGGGGGCAGCTGACTGAAGCCGTACGCCGCAA
ACCTTATTCGGTGGTATTGCTGGACGAGATTGAAAAGGCACATCCTGATGTATTCAACATTTTATTGCAGGTTTTGGACG
ATGGCAGGTTAACGGATAATAAAGGCCGCGTGGTGAACTTTAAAAATACAATTATCATCATGACCTCTAATATTGGTTCA
CACCTGATCCAGGATAATTTTAAATCGCTGAATGATGAAAACAGGGACGAGGTAATTGCCAAAACTAAAAATGAACTGTT
TGAACTGTTAAAGCAAACCATCAGGCCCGAATTTTTAAACAGGATTGATGAACTGATCATGTTTACCCCACTTAACCGCA
ATGAGCTGAGGGACATTGTAAACCTGCAGTTTAAACAGGTACAGGATACCCTTTCAGAAATGGGAATAGAAATAGAGGCT
TCAACGGAGGCATTGGACTGGCTGGCAGAATTGGGTTACGACCCGCAGTTTGGTGCCCGTCCGTTAAAACGTGTGATCCA
GAAACGCATTTTAAATGAGCTTTCCAAAGAAATACTTGCCGGAAAAGTGGATAAAGAAAGTAAGATCAAACTGGATATGT
TTGATCACAAATTTGTATTTCTTAATAATAAATAA

Protein sequence :
MNFNNFTIKAQEAIQQASEIATGNQQQAIETAHILKGLLTVDENVVSYVLKKLNVNLNVLNQQLDAQIEKFPKVTGSSPY
LTSGSNSALQKANSYLKEFKDEFVSVEHVLLGLLSVNDDTAKHLKDQGVTEKDLKKAIIALRGDNHVTGQNAEATYNALN
KYARNLNEYAESGKLDPVIGRDEEIRRVIQILSRRTKNNPILIGEPGVGKTAIAEGIAFRIIKGDVPTNLKTKTVYSLDM
GALIAGAKYKGEFEERLKAVVKEVTQSDGDIILFIDEIHTLVGAGGGEGAMDAANILKPALARGELRAIGATTLDEYQKY
LEKDKALERRFQKVMVDEPDTQDAISILRGLKERYETHHKVRIKDEAIIAAVEMSQRYIADRFLPDKAIDLMDEAASKLR
LEMDSVPEKVDELNRKIMQLEIEREAIKRENDTRKVKSLAEEIANLSAERDEIKAKWQGEKDLVDNINNEIEQIENYKLE
ADQAERAGDYGKVAEIRYGKIKEAQDKVEKLKVQLESQQTEGRMLKEEVTADDIAGVVGRWTGIPVTKLVSSEREKLLNL
ETELHKRVAGQHEAIEAISDAIRRSRAGLQDKRKPIGSFIFLGTTGVGKTELAKALAEFLFNDENAMTRIDMSEYQERHA
VSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNIGS
HLIQDNFKSLNDENRDEVIAKTKNELFELLKQTIRPEFLNRIDELIMFTPLNRNELRDIVNLQFKQVQDTLSEMGIEIEA
STEALDWLAELGYDPQFGARPLKRVIQKRILNELSKEILAGKVDKESKIKLDMFDHKFVFLNNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-154 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Phep_1456 YP_003091732.1 ATP-dependent chaperone ClpB VFG2076 Protein 5e-125 44
Phep_1456 YP_003091732.1 ATP-dependent chaperone ClpB VFG2084 Protein 6e-107 43