Gene Information

Name : guaA (Phep_0993)
Accession : YP_003091276.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1159862 - 1161388 bp
Length : 1527 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCTAGAAAAAATCATAATTCTCGATTTTGGTTCCCAATATACACAGTTAATTGCCCGTAGGGTGCGTGAGTTAAACGT
TTATTGTGAAATTCACCCATTTAACAACATTCCTGAAATCGGTTCAGACGTTAAAGGTATCATCCTGTCAGGTAGCCCAT
ATTCTGTCCGTCAGAAAGACGCCCCACAGGTAGATCTTAACAAATTTGACAAACATCCTATGCTGGCGGTTTGTTATGGT
GCACAATACATCGCACAACATGCAGGCGGTGAAGTACAAGCCTCTTCTACACGTGAATATGGCAGGGCCCACCTGAATTT
CGTTGCCGAAGGCAATAAATTATTTAAAAATATTACTGCAGGTTCGCAGGTATGGATGTCACATGGCGATACCATTACGA
AAGTACCTGCAAACTTTGAACTGATAGCCAGTACAGATAGTGTAAAAGTTGCAGCTTACCAGGTTAAAGACACACAAACT
TATGCCATACAGTTTCACCCTGAGGTTACACATAGCACCGATGGTAGACAATTGCTGGAGAATTTTCTTGTCGGCATTTG
CGGATGTAAGCAGGAGTGGACGCCCGATGCTTTTGTAGAAACCACCATTGCTGATTTAAAAGAAAAACTGGGCAATGATA
AAGTGGTACTGGCCCTTTCAGGAGGGGTAGACTCGAGTGTAGCTGCTATCTTATTGCATAAGGCCATAGGTAAAAACCTG
CACTGTATATTTGTAGACAATGGCTTGTTAAGAAAAGATGAGTATGCTGCCGTACTGGAACAATATAAACACCTTGGTTT
GAACATCAAAGGTGTAGATGCAAAAGATCGTTTCTTGAGCCAGCTTGCCGGAGTTTCTGATCCTGAGTTGAAACGTAAAG
CCATTGGAAGGGTGTTTATTGAAGTGTTTGATGATGAAGCGCACCAGGTACAGGATGTGAAGTGGCTGGCACAGGGTACC
ATATATCCTGATATCATAGAATCCGTTTCTGTAAAAGGACCTTCAGCTACCATTAAATCGCACCATAACGTAGGTGGTTT
GCCCGATTTCATGAAACTTAAAGTTGTGGAGCCCCTGAATACTTTGTTTAAGGACGAGGTGAGAAGGGTGGGGACTTCTT
TGGGACTGGAGCACTTTATCATCGGACGTCACCCTTTTCCGGGACCTGGATTAGCGATAAGGATACTGGGCGAGGTTACT
GCTGAAAAAGTAGCCATTCTTCAGGAAGCAGATGCCATTTATATCAATAACTTAAAAGAAGCAGGTTTATACGATAAGGT
ATGGCAGGCCGGAGCCATTTTCCTGCCGGTTCAATCGGTAGGGGTAATGGGAGATGAGCGTACTTACGAAAATGCAATAG
CCCTTCGTGCTGTTGAATCTGTTGATGGCATGACTGCCGACTGGTGTCATCTGCCTTATAACGTACTCGCAAAAATTTCT
AATGAAATAATTAACAAAGTAAAAGGAATTAACCGCGTTGTATATGACATTAGCTCAAAACCACCAGCTACTATTGAGTG
GGAATAA

Protein sequence :
MLEKIIILDFGSQYTQLIARRVRELNVYCEIHPFNNIPEIGSDVKGIILSGSPYSVRQKDAPQVDLNKFDKHPMLAVCYG
AQYIAQHAGGEVQASSTREYGRAHLNFVAEGNKLFKNITAGSQVWMSHGDTITKVPANFELIASTDSVKVAAYQVKDTQT
YAIQFHPEVTHSTDGRQLLENFLVGICGCKQEWTPDAFVETTIADLKEKLGNDKVVLALSGGVDSSVAAILLHKAIGKNL
HCIFVDNGLLRKDEYAAVLEQYKHLGLNIKGVDAKDRFLSQLAGVSDPELKRKAIGRVFIEVFDDEAHQVQDVKWLAQGT
IYPDIIESVSVKGPSATIKSHHNVGGLPDFMKLKVVEPLNTLFKDEVRRVGTSLGLEHFIIGRHPFPGPGLAIRILGEVT
AEKVAILQEADAIYINNLKEAGLYDKVWQAGAIFLPVQSVGVMGDERTYENAIALRAVESVDGMTADWCHLPYNVLAKIS
NEIINKVKGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-121 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-121 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-121 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-109 46