Gene Information

Name : Dfer_5048 (Dfer_5048)
Accession : YP_003089413.1
Strain : Dyadobacter fermentans DSM 18053
Genome accession: NC_013037
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 6100935 - 6101678 bp
Length : 744 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
GTGCGCATTCTAGGAATAATACCGGCCCGCTACGCTTCTACACGCTTCCCTGCCAAGGCTTTGGTGGACATCGGCGGCAA
AAGCATGATCCAGCGGGTGTACGAACAGGCGTCCAAAGCTACTCAACTGGATCAGGTTATCGTAGCGACGGACGATGAAA
GAATATTGTACCACGTCCGCGAGTTCGGCGGCCAGGCCGTGATGACTTCGCAGGACCACCAGAGCGGCACCGACCGCTGC
TTCGAAGCGCTTTCGCAAACAGAGGGCACTTACGACTACGTGATCAACATCCAGGGCGACGAACCATTCATCAGCCCCGA
GCCGATCGATCATCTAGCCTCTGTACTAAATGGCGAAACCGAGCTCGCCACATTGGTGAAAGTCATCGACAATGATGAAA
TTCTCTTCAATGTGAATGTGCCAAAGGCGGTTTTGAATAAGCGAAATGAAGTGATGTATTTCAGCCGGCAAACAATCCCT
TACCTGCGCAACGCACAAAGCCAGGAGGAGTTTCTGAAATCACACGTTTTTTACAAACACATCGGCATTTACGCCTACCG
GACCGACGTTTTGGCCGAAATCACGAAGCTGCCGGTATCGGCACTGGAAAAAGCGGAAGCTTTGGAACAGCTTCGCTGGC
TCGAAAACGGTTACGCGATCAAGGCCGTGGTCACTTCCGACGATTCGCACGGTGTGGACACGCCCGACGACCTCGATCGC
GTTACGCGAAAATTTTTGCCGTAA

Protein sequence :
MRILGIIPARYASTRFPAKALVDIGGKSMIQRVYEQASKATQLDQVIVATDDERILYHVREFGGQAVMTSQDHQSGTDRC
FEALSQTEGTYDYVINIQGDEPFISPEPIDHLASVLNGETELATLVKVIDNDEILFNVNVPKAVLNKRNEVMYFSRQTIP
YLRNAQSQEEFLKSHVFYKHIGIYAYRTDVLAEITKLPVSALEKAEALEQLRWLENGYAIKAVVTSDDSHGVDTPDDLDR
VTRKFLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-40 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-40 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-40 45