Gene Information

Name : guaA (Dfer_2697)
Accession : YP_003087078.1
Strain : Dyadobacter fermentans DSM 18053
Genome accession: NC_013037
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3329318 - 3330847 bp
Length : 1530 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTGAACAAATTCTGATTTTAGATTTTGGCTCACAGTACACCCAGTTAATTGCACGGAGAGTTCGCGAACTGAATGT
TTATTGTGAAATCCACCCATACAACAATTTCCCCGAACTCACTCCCAACGTCAAAGGTGTCATTCTCTCAGGAAGCCCCT
GTTCTGTAAGGGACGAAGATTCTCCCCGGGTAGATCTCAACAAATTTCGCAAAACATTGCCCCTGCTCGGCGTATGCTAT
GGCGCACAGTTGCTCGCACAGGAGCTGGGCGGCGATGTGAAACCTTCGCAGCACCGTGAATATGGCCGCGCGAAGCTGGA
ACTCGGCGATCCGGACTCGTCGCTGCTGGCAGGCTTGTCGGAATCATCGCAGGTGTGGATGTCGCATGGTGATACTATTA
TGCGCGCGCCGCAGAATTTCCACGTGATCGCTTCTACGGAGTCCGTGAAAGTGGCTGCATTTAAAGTGGAGGACGAATTA
ACCTACGGTATTCAGTTCCACCCCGAGGTAACGCACACAACGGAAGGTAAAAAGCTGCTGCACAATTTTGTAGTGAACAT
TTGCGGTTGCAAGCAGGACTGGACTTCCGAGTCGTTCGTAGAGCATACGATCGAGCAGCTTCGCAAGAAATTGGGTAACG
ACAAGGTCGTAATGGCACTTTCGGGTGGCGTAGATTCCACGGTGGCTGCTACGCTGGTACACCACGCGATCGGTCAGAAT
TTGTATTGTATTTTCGTAGATAACGGTCTGCTGCGTAAGGATGAGTTTGAGCAAGTGCTGCATTCTTACCAGGACATGGG
CCTCAATATCAAAGGTGTAGATTCTAAATCACACTTTTACCAGCAACTCGACGGCCTGAGCGATCCGGAAGCGAAACGCA
AGGCGATCGGCAAGTCGTTCATCGATATTTTCGATCAGGAAGCGCATTTGATCGAGGACGTGAAATGGCTTGGACAGGGT
ACTATTTACCCCGACGTGATCGAATCCGTTTCCGTCAAAGGACCTTCGGCGACCATCAAGTCACACCACAACGTGGGTGG
TTTGCCCGATTTCATGAAACTGAAAGTCGTGGAGCCGCTGAATACATTGTTTAAAGATGAAGTAAGGGCGGTTGGACGTA
CACTGGGTATCGACGAGAAGATCCTTAGCCGCCACCCGTTCCCGGGACCAGGCCTGGCGATCCGCATTTTAGGAGACATT
ACGGAGGAAAAAGTAGCGATTTTGCAGGAGGTAGACGCGATATTTATCGGCGGCCTCCGCAAATGGGACCTTTACAAAGA
CGTTTGGCAGGCAGGCGCAATGCTCCTTCCCGTGCAGAGCGTGGGCGTAATGGGCGACGAGCGCACGTATGAGCGCGTGG
TAGCCCTGCGCGCGGTAACTTCGGTGGACGGTATGACCGCCGACTGGGCGCATTTGCCCTATGATTTCCTCGCGGAAGTT
TCCAACGACATTATCAACAAGGTGAAAGGGGTGAACAGGGTCGTTTACGACATTTCTTCCAAACCGCCTGCAACCATTGA
ATGGGAATAA

Protein sequence :
MTEQILILDFGSQYTQLIARRVRELNVYCEIHPYNNFPELTPNVKGVILSGSPCSVRDEDSPRVDLNKFRKTLPLLGVCY
GAQLLAQELGGDVKPSQHREYGRAKLELGDPDSSLLAGLSESSQVWMSHGDTIMRAPQNFHVIASTESVKVAAFKVEDEL
TYGIQFHPEVTHTTEGKKLLHNFVVNICGCKQDWTSESFVEHTIEQLRKKLGNDKVVMALSGGVDSTVAATLVHHAIGQN
LYCIFVDNGLLRKDEFEQVLHSYQDMGLNIKGVDSKSHFYQQLDGLSDPEAKRKAIGKSFIDIFDQEAHLIEDVKWLGQG
TIYPDVIESVSVKGPSATIKSHHNVGGLPDFMKLKVVEPLNTLFKDEVRAVGRTLGIDEKILSRHPFPGPGLAIRILGDI
TEEKVAILQEVDAIFIGGLRKWDLYKDVWQAGAMLLPVQSVGVMGDERTYERVVALRAVTSVDGMTADWAHLPYDFLAEV
SNDIINKVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-120 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-120 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-120 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-111 47