Gene Information

Name : leuS (Dfer_2634)
Accession : YP_003087016.1
Strain : Dyadobacter fermentans DSM 18053
Genome accession: NC_013037
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 3251399 - 3254308 bp
Length : 2910 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCGAGTACAGTCATCGCGAAATAGAAAAAAAATGGCAGGATTTCTGGCAGAAGAACGGCACATTCAGCGTGTCCAA
TGAGTCGGAGTTGCCGAAGTATTATGTGTTGGATATGTTTCCCTACCCTTCGGGCGCAGGGCTGCATGTGGGGCATCCGC
TGGGGTATATTGCCTCGGATATCTATTCCCGTTACAAAAGGCTGAAAGGCTTCAACGTGCTGCATCCGATGGGCTTCGAT
AGCTTCGGATTGCCCGCCGAGCAATACGCCATCCAAACCGGCCAGCACCCGGCCATTACCACCGAGCAGAATATCAGCCG
CTATATCGAGCAGCTGAAAAACCTGGGACTCAGCTACGACTGGAACCGCGAAGTGCGGACGTCCGACCCGGGCTACTATA
AATGGACGCAATGGATTTTCTCGGAGCTGTTCAACAGCTGGTACAACAACGATACCGACCAGGCGGAGCCGATTGAAACC
CTGACCGCGAAATTCGCGCAGGAAGGTAATGCCAAAATCAATGCACCTGCGGATGAAGATACCCCCGCATTCACTGCCGA
AGAGTGGAATGCATGGTCGGAAGAGGTACAATATAAGATGACATTGAAATACCGCCTGACCTACGTCGCCGACGCAACCG
TAAACTGGTGCCCCGGCCTGGGATCGGTATTGTCGAACGACGAGGTGAAAGACGGTGTTTCCGAACGCGGCGGCTTCCCC
GTGATCCAGAAACTGATGCGCCAATGGATGATGCGCATCACCGCATACGCACAGCGATTGATCGACGGCCTGGACACGGT
GGATTGGACGGAGTCATTGAAAGAGCAGCAGCGGAACTGGATCGGACGTTCGGTTGGAGCGTTGGTCAAATTTCAGGTTT
GGGAGGAAAGGGAAGATGGAGGAAAGGGAGAAAGTGGTATTGTAAATTCCCTTTCCTCCTTTCCTCCCTCTATCGAAGTG
TTCACAACACGAGTAGACACGATTTACGGCGTTACGTTTATGGTAATCGCGCCGGAGCATGAGCTTGTGGATGTGATCAC
GACGCCGGAGCAGCGGGCGGAAATTGATGACTACATTGCCATGACGCAGAAGAAATCGGAGCGCGACCGGATGTCGGACG
TGAAAACGGTTTCGGGTGCATTCACGGGTGCGTACGTGCTCAATCCGTTCAGCGGAGAAAAGGTGCCGGTTTACATTGCC
GACTACGTGCTGGCAGGCTACGGAACCGGGGCGGTCATGGCCGTACCATCCGGCGACCAGCGCGACTGGAACTTCGCCAA
GCATTTCAACCTGCCCATTATCCCGATCCTCGACGCGCAAAAGGACATTGAAACACAAGCCGACGCGACGAAAGAAGGAA
AATATATCAATTCAGGCATTATCGACGGATTGACCTACAAAGAGGCCACCGAAAAGCTGATCAATGTACTGGAAGAAAAA
GGATTAGGTAAAGGAAAAATCAACTACCGCCTGCGCGACGCGGTGTTCAGCCGCCAGCGTTACTGGGGCGAGCCGGTGCC
TGTTTATTACAAAAATGACAGCGAAGGCCAGCCGGTACCATATCTGCTCGACTTGAACGAGCTGCCGTTGAACCTGCCGG
AAGTTGATAAATACCTGCCGACTGAAAACGGAGAGCCGCCGCTGGGCCGCGCTGTTGGGTGGTCTTATGGCTCAGGTGTT
GGCTATAATTCGGGCTCTGGTCACGGTTACGAAACCGGAGCAGGTTATAGCTACGAGCTCAGCACCATGCCGGGCTGGGC
GGGCAGCAGCTGGTACTGGTACCGCTACATGGACCCGAAAAACGAGAACGAATTCGCATCGAAAGAGGCGATCGGCTATT
GGAAAGATGTGGATTTGTACATCGGCGGCACCGAGCACGCGACGGGGCACTTACTGTACAGCCGTTTCTGGAACAAATTC
ATGAAAGACCGCGGATTTGTGCAGGAAGAGGAGCCGTTCAAAAAGCTCATCAACCAGGGCATGATCCAGGGGCGCAGCAA
CTTCGTGTACCGCGTCAAAGGAGAGGATTACAGCAAGCCTGTGTTTGTAAGCGCCGGTTTGAAATCGCAATATGAGGTTT
CGGCATTGCACGTGGATGTGAATATTGTGGAAAACGACGTGCTGGATGTGGACAAGTTCAAAGCGACGCGGCCGGATATC
GCTGGCGAGCATGCTGAGTTCATCCTCGAAGACGGCAAATACATTTGCGGTGTGGAAGTGGAGAAAATGTCGAAATCGAA
GTTTAACGTCGTGAACCCGGACGATATCGTGGAGCGCTACGGGGCCGATACCCTGCGGTTGTACGAAATGTTCCTCGGGC
CGCTCGATCAGGCGAAACCCTGGAATACCAATGGAATCGACGGAACGTACCGCTTCATCCGTAAGCTGTGGCGCCTGTTT
TACACCGAAACCGGCCAGTGGCAGGTGAAAGACGTTCCCGCGAAGCCCGACGAATTGAAGACTTTGCACAAAACGATCAA
AAAGATCGGTGAGGACATCGAAAACTTCTCGTTCAACACCGCAGTGAGTGCGTTTATGGTGTGCGTGAATGAGCTCGGCA
GCCAGAAATGCCAGAGCAAAGAAGTATTGCAGCAATTGGTAATCCTGCTTTCGCCCTACGCGCCGCATATTTCGGAAGAA
TTGTGGACGGCATTGGGTAATGAAGCAGGAGGTGTTTCCAAAGCCGAATTCCCGGTTTTTGAAGCCAAATACGTGCAGGA
TTCAGTATTCGAATATCCGGTGCAGATCAATGGAAAAGTGCGCGCGTCGTTGACATTCCCGCTGGACACGCCGGCGGCGG
ACATCGAGAAGGAGGTATTGGCCGACGTAACCGTTCAGAAATGGATGGAAGGCAAGCCTGCCAAAAAAGTGATCGTCGTT
CCAAAACGGATTGTGAACGTGGTGATCTGA

Protein sequence :
MSEYSHREIEKKWQDFWQKNGTFSVSNESELPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYSRYKRLKGFNVLHPMGFD
SFGLPAEQYAIQTGQHPAITTEQNISRYIEQLKNLGLSYDWNREVRTSDPGYYKWTQWIFSELFNSWYNNDTDQAEPIET
LTAKFAQEGNAKINAPADEDTPAFTAEEWNAWSEEVQYKMTLKYRLTYVADATVNWCPGLGSVLSNDEVKDGVSERGGFP
VIQKLMRQWMMRITAYAQRLIDGLDTVDWTESLKEQQRNWIGRSVGALVKFQVWEEREDGGKGESGIVNSLSSFPPSIEV
FTTRVDTIYGVTFMVIAPEHELVDVITTPEQRAEIDDYIAMTQKKSERDRMSDVKTVSGAFTGAYVLNPFSGEKVPVYIA
DYVLAGYGTGAVMAVPSGDQRDWNFAKHFNLPIIPILDAQKDIETQADATKEGKYINSGIIDGLTYKEATEKLINVLEEK
GLGKGKINYRLRDAVFSRQRYWGEPVPVYYKNDSEGQPVPYLLDLNELPLNLPEVDKYLPTENGEPPLGRAVGWSYGSGV
GYNSGSGHGYETGAGYSYELSTMPGWAGSSWYWYRYMDPKNENEFASKEAIGYWKDVDLYIGGTEHATGHLLYSRFWNKF
MKDRGFVQEEEPFKKLINQGMIQGRSNFVYRVKGEDYSKPVFVSAGLKSQYEVSALHVDVNIVENDVLDVDKFKATRPDI
AGEHAEFILEDGKYICGVEVEKMSKSKFNVVNPDDIVERYGADTLRLYEMFLGPLDQAKPWNTNGIDGTYRFIRKLWRLF
YTETGQWQVKDVPAKPDELKTLHKTIKKIGEDIENFSFNTAVSAFMVCVNELGSQKCQSKEVLQQLVILLSPYAPHISEE
LWTALGNEAGGVSKAEFPVFEAKYVQDSVFEYPVQINGKVRASLTFPLDTPAADIEKEVLADVTVQKWMEGKPAKKVIVV
PKRIVNVVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-114 41