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Name : leuS (NMO_0273) Accession : YP_003082506.1 Strain : Neisseria meningitidis alpha14 Genome accession: NC_013016 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 289237 - 291873 bp Length : 2637 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGACTATGCAAGAACAATATCAACCCGCCGCCATCGAGCCTGCGGCGCAGAAAAAATGGGACGACGCCCGTATTTTCAA CGTCTCCGAAGACGCTTCCAAACCCAAATATTATTGCCTCTCCATGTTCCCCTATCCCAGCGGCAAGCTGCATATGGGGC ATGTGCGCAACTACACCATCGGCGATGTATTGAGCCGCTTCAAACTTTTAAACGGCTTCAACGTCATGCAGCCTATGGGT TGGGACGCGTTCGGCATGCCGGCGGAAAACGCGGCGATGAAAAACAACGTCGCCCCTGCCGCTTGGACGTACGATAACAT CGAATACATGAAAACCCAGCTCAAAAGCCTGGGTTTTGCGATTGACTGGGAACGCGAAGTCGCTACCTGCAAACCCGAAT ACTACCGTTGGGAACAATGGCTGTTTACCAAGCTGTTTGAAAAAGGCATCGTCTATCGCAAAAACGGCACGGTAAACTGG GACCCGGTTGACCAAACCGTCCTTGCTAACGAGCAAGTCATCGACGGACGCGGCTGGCGTTCCGGCGCGTTGATCGAAAA ACGCGAAATCCCGATGTATTACTTCAAAATCACGGATTACGCCGAAGAGCTGCTCAACGACTTGGACAAACTGGAACACT GGCCGGAACAAGTCAAAACCATGCAGCGCAACTGGATCGGCAAATCTCGCGGCATGACCGTGCGCTTTGCTGTTTCAGAC GACAGCAAACAAGGCTTGGAAGGCGATTACGCGAACTTCCTGCAAGTTTACACCACCCGTCCCGACACGCTGATGGGCGC GACTTATGTTGCAGTTGCCGCCGAGCATCCGCTGGCAACCGCCGCAGCCGCCGACAAACCCGAATTGCAGGCATTTATCG CCGAATGCAAAGCGGGCTCCGTTGCCGAAGCCGATATGGCGACGATGGAGAAAAAAGGCGTGCCGACCGGCCGCTACGTC GTCAACCCGCTCAACGGCGACAAGCTGGAAGTGTGGATTGCCAACTATGTATTGTGGGGCTACGGCGACGGCGCAGTGAT GGCTGTTCCGGCGCATGACGAACGCGATTTTGAGTTCGCCACCAAATACAATCTGCCGAAAAAACAAGTCATTGCCGTCG GCGACAACGCATTTGACGAAAACCAATGGCAAGAATGGTACGGCGACAAAGAAAACGGCGTATTGGTCAACAGCGGCGAC TTGGACGGCTTGGATTTTCAGACGGCATTTGATGCCGTTGCCGCCAAGCTGCAAAACCAAGGCGCGGGCGAACCGAAAAC CCAATACCGCCTGCGCGACTGGGGCATTTCGCGCCAACGCTACTGGGGCTGCCCGATTCCCATCGTCCATTGCGAACAAT GCGGCGACGTCCCCGTCCCTGCCGACCAATTGCCGGTCGTTTTGCCTGAAAACGTCGTACCCGACGGCATGGGTTCGCCG CTGGCAAAAATGCCCGAGTTTTACGAAACTGCCTGCCCATGCTGCGGCGGCGCGGCAAAACGCGAAACCGACACCATGGA CACCTTCATGGAATCGAGCTGGTATTTCTTCCGCTATATGTCGCCAAAATTTTCAGACGGCATGGTCGATCCTGCCGCCG CGAAATACTGGGGCGCGGTCGACCAATACATCGGCGGCATCGAACACGCGATTTTGCACCTCTTGTACGCGCGTTTCTTC ACCAAACTGATGCGCGACGAAGGTCTAGTCAATGTTGACGAACCGTTTGAACGCCTGCTGACGCAAGGCATGGTCGTTTG CGAAACCTACTACCGCGAAAACGACAAAGGCGGCAAAGATTGGATCAACCCCGCCGATGTCGAGCTGACGTTCGACGACA AAGGCCGCCCCATTTCCGCCGTCCTCAAAGCCGACGGGCTGCCCGTCGTCATCAGCGGCACGGAAAAAATGTCCAAGTCC AAAAACAACGGCGTCGATCCGCAAGAGCTGATTAACGCCTACGGCGCGGACACCGCCCGCCTGTTCATGATGTTCGCCGC ACCGCCCGAACAGTCCCTCGAATGGAGCGACAGCGGCGTCGAAGGCGCGCACCGCTTCCTGCGTCGCTTGTGGCGTACCG TTTACGAATACCTGAAACAAGGCGAAGCAGTCAAAGCATTTGCAGGCAGCCAAGACGGTTTGTCTAAAGAACTCAAAGAC CTGCGCCACAAACTGCATTCCACCATCGCCAAAGTCAGCGACGACTACGGCCGCCGCCAACAGTTCAACACCGCCATCGC CGCCGTGATGGAATTGCTCAACCAATACGACAAAACCGACACCGGCGGCGAACAAGGCCGCGCCGTCGCCCAAGAAGTAT TGGAAACCGCCGTACGCCTGCTGTGGCCCATCGTGCCGCACATCTGCGAAACCCTGTGGAGCGAATTGAACGGTGCGAAA CTGTGGGAAGCAGGCTGGCCGACAGTCGACGAAGCCGCCTTGGTCAAATCCGAAATCGAAGTCATGGTTCAAGTCAACGG CAAACTGCGCGGTAAAATCACCGTCGCCGCCGACGCATCCAAAGCCGACCTCGAAGCCGCCGCACTCGCCACCGAAGGCG CGGTGAAATTCATGGAAGGCAAACCGGCGAAGAAAATCATCGTCGTACCCGGACGCTTGGTGAATATCGTCGTCTAA Protein sequence : MTMQEQYQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMG WDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWEREVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNW DPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSD DSKQGLEGDYANFLQVYTTRPDTLMGATYVAVAAEHPLATAAAADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYV VNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFATKYNLPKKQVIAVGDNAFDENQWQEWYGDKENGVLVNSGD LDGLDFQTAFDAVAAKLQNQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEQCGDVPVPADQLPVVLPENVVPDGMGSP LAKMPEFYETACPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVDPAAAKYWGAVDQYIGGIEHAILHLLYARFF TKLMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPISAVLKADGLPVVISGTEKMSKS KNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGEAVKAFAGSQDGLSKELKD LRHKLHSTIAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGGEQGRAVAQEVLETAVRLLWPIVPHICETLWSELNGAK LWEAGWPTVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALATEGAVKFMEGKPAKKIIVVPGRLVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-138 | 41 |
