Gene Information

Name : mutS (NMO_0017)
Accession : YP_003082266.1
Strain : Neisseria meningitidis alpha14
Genome accession: NC_013016
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 14127 - 16721 bp
Length : 2595 bp
Strand : -
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGTCCAAATCCGCCGTTTCCCCAATGATGCAGCAATACCTCGGCATCAAAGCGCAACATACCGACAAACTGGTGTTTTA
CCGTATGGGCGATTTTTACGAGATGTTTTTCGACGATGCGGTAGAAGCGGCAAAACTTTTGGATATTACCCTGACCACGC
GCGGGCAGATGGACGGCGTACCGATTAAAATGGCAGGCGTGCCGTTTCACGCCGCCGAACAATATCTGGCGCGCCTGGTC
AAGTTGGGCAAAAGCGTGGCGATTTGCGAACAGGTCGGCGAAGTCGGCGCAGGCAAAGGGCCGGTGGAACGCAAAGTCGT
GCGCATCGTAACGCCTGGCACGCTAACCGATTCCGCATTGCTGGAAGACAAGGAAACCAACCGCATCGTTGCCGTGTCCC
CCGACAAAAAATACATCGGTTTGGCGTGGGCATCGCTGCAAAGCGGCGAATTCAAAACCAAGCTGACAACTGTGGATAAA
TTGGACGACGAACTGGCGCGCCTGCAGGCGGCGGAAATTCTGTTGCCGGACAGTAAAAACGCACCGCAACTTCAGACGGC
ATCGGGTGTTACGCGCCTGAACGCGTGGCAGTTTGCCGCCGACGCAGGGGAGAAACTGCTGACGGAATATTTCGGCTGCC
AGGATTTGCGCGGCTTCGGTTTGGACGGCAAAGAACACGCCGTTGCGATTGGCGCGGCAGGTGCGCTGTTGAACTATATC
CGCCTGACGCAAAACCTGATGCCGCAACATTTGGACGGCCTGTCGCTCGAAACCGACAGCCAATATATCGGTATGGATGC
CGCCACGCGCCGCAATCTCGAAATCACGCAAACCCTCTCCGGCAAAAAATCGCCGACCCTGATGTCCACGCTCGACCTTT
GCGCCACCCATATGGGCAGCCGCCTGTTGGCATTGTGGCTGCACCACCCTTTACGCAACCACGCCCACATCCGAGCGCGC
CAAGAAGCCGTTGCCGCACTGGAAAGCCAATACGAACCCCTCCAGTGCCGTCTGAAAAGCATTGCCGACATCGAACGCAT
CGCCGCCCGTATTGCCGTGGGTAACGCCCGCCCGCGCGACCTCGCCGCCCTGCGCGACAGCCTGTTTGCCCTGTCCGAAA
TCGAATTGTCCGCCGAGTGCAGCAGTCTCTTAGGAACCCTCAAAGCCGTTTTCCCGGAAAACCTATCCACAGCCGAACAG
CTCCGCCAAGCCATTTTGCCCGAACCTTCCGTCTGGCTGAAAGACGGCAATGTCATCAACCACGGTTTTCATCCCGAACT
GGACGAATTGCGCTGCATTCAAAACCATGGCGACGAATTTTTGCTGGATTTGGAAGCCAAGGAACGCGAACGTACCGGTT
TGTCCACACTTAAAGTCGAGTTCAACCGCGTTCACGGCTTTTACATTGAATTGTCCAAAACCCAAGCCGAACAAGCACCT
GCCGACTACCAACGCCGGCAAACCCTCAAAAACGCCGAACGCTTCATCACGCCGGAACTGAAAGCCTTTGAAGACAAAGT
GCTGACTGCTCAAGAGCAAGCCCTCGCCTTAGAAAAACAACTCTTTGACGGCGTATTGAAAAACCTTCAGACGGCATTGC
CGCAGCTTCAAAAAGCCGCCAAAGCCGCCGCCGCGCTGGACGTGTTGTCCACATTTTCAGCCTTGGCAAAAGAGCGGAAC
TTCGTCCGCCCCGAGTTTGCCGACTATCCGGTTATCCACATCGAAAACGGCCGCCATCCCGTTGTCGAACAGCAGGTACG
CCACTTCACCGCCAACCACACCGACCTCGACCACAAACACCGCCTCATGCTGCTCACCGGCCCCAATATGGGCGGCAAAT
CCACCTATATGCGCCAAGTCGCGCTGATTGTTTTATTGGCACACACCGGCTGTTTCGTGCCTGCCGATGCCGCCACAATC
GGACCCATCGATCAAATCTTCACCCGCATCGGCGCATCGGACGATCTCGCCTCCAACCGCTCCACCTTCATGGTCGAAAT
GAGCGAAACCGCCTACATCCTGCATCACGCCACCGAACAAAGCCTTGTTTTAATGGACGAAGTCGGACGTGGTACTTCCA
CTTTCGACGGCCTCGCCCTCGCGCACGCCGTTGCCGAACACCTGCTGCAAAAAAACAAATCCTTCAGCCTGTTTGCCACC
CACTATTTCGAGCTGACCTACCTGCCCGAAACCCACGCCGCCGCCGTCAATATGCACCTTTCCGCGCTCGAACAGGGACA
GGACATCGTGTTCCTGCACCAAATCCAACCGGGGCCCGCCGGAAAAAGCTACGGCATCGCCGTCGCCAAACTCGCCGGCC
TGCCTGTACGCGCATTGAAATCCGCCCAAAAGCATTTGAACGAACTGGAAGACCAAGCCGCCGCAAACCGTCCCCAACTG
GATATTTTCAGTACCATGCCGTCTGAAAAAGGAGATGAACCGAATGTGGAAAGCTTTGTGGACAAAGCAGAGGAAAAACA
TTTTGAAGGTATATTGGCAGCAGCCCTGGAGAAACTCGATCCCGACAGCCTGACCCCGCGCGAAGCATTGTCAGAACTGT
ACCGTCTGAAAGATTTGTGCAAATCCGTATCTTAA

Protein sequence :
MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLV
KLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
LDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDGKEHAVAIGAAGALLNYI
RLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNHAHIRAR
QEAVAALESQYEPLQCRLKSIADIERIAARIAVGNARPRDLAALRDSLFALSEIELSAECSSLLGTLKAVFPENLSTAEQ
LRQAILPEPSVWLKDGNVINHGFHPELDELRCIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAP
ADYQRRQTLKNAERFITPELKAFEDKVLTAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERN
FVRPEFADYPVIHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATI
GPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFAT
HYFELTYLPETHAAAVNMHLSALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNELEDQAAANRPQL
DIFSTMPSEKGDEPNVESFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRLKDLCKSVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 5e-167 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_003082266.1 DNA mismatch repair protein MutS VFG0562 Protein 7e-177 50