Gene Information

Name : tkt (NMO_1289)
Accession : YP_003083457.1
Strain : Neisseria meningitidis alpha14
Genome accession: NC_013016
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1360612 - 1362591 bp
Length : 1980 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCTCAACTGGCAAACGCAATCCGCTTCCTCTCCGCAGATGCCGTTCAAAAAGCAAATTCCGGCCACCCCGGCGCGCC
TATGGGTATGGCGGAAATGGCGGAAACATTGTGGACGAAATTCCTCAATCACAATCCCGCCAACCCCAAATTCTACAACC
GCGACCGCTTCGTCCTCTCCAACGGCCACGCGTCTATGCTGTTGTACAGCCTGCTGCACCTGACCGGCTACAACCTAAGC
ATTGAAGACTTGAAAAACTTCCGCCAACTGCACAGCAAAACCCCCGGCCACCCCGAATACGGCTACACCGACGGCGTGGA
AACCACGACCGGCCCGTTGGGGCAAGGGATTGCCAACGCGGTGGGTATGGCATTGGCAGAAAAAATCCTTGCCGCCGAAT
TTAATAAAGACGGTTTGAACATCGTCGATCATTACACCTACGTCTTTATGGGCGACGGCTGTCTGATGGAAGGCGTATCG
CACGAAGCCTGTTCGCTCGCCGGCACCTTGGGCTTGGGCAAACTGATTGTTTTGTATGATGACAACAATATTTCCATTGA
TGGTAAAGTGGACGGCTGGTTTACCGAAAACATCCCGCAACGCTTTGAAAGCTACGGCTGGCACGTCGTTCCCAATGTAA
ACGGTCATGACACCGCCGCCATTCAAGCCGCCATCGAAGCCGCACGTGCCGAAACCGGCAAACCGTCCATCATCTGCTGC
AAAACCTTAATCGGCAAAGGCAGTGCCAACAAAGAAGGCAGCCACAAAACCCACGGCGCACCTTTGGGCGCGGACGAAAT
CGAAGCCACGCGCAAACATTTGGGCTGGACTTACCCCGCCTTTGAAATCCCGCAAGAAATTTACGATGCGTGGAATGCCA
AAGAACAAGGCGCGAAACTGGAAGCCGACTGGAACGAACTGTTCGCGCAATATCAAGCCAAATATCCTGCCGAAGCCGCA
GAATTTGTGCGCCGTATGGATAAAAAGCTGCCGGACAATTTCGATGAATACGTTCAAGCCGCATTGAAAGAAGTGTGCGC
CAAAGCCGAAACCATCGCCACCCGCAAAGCCAGCCAAAACAGCATCGAAATCTTGGCAAAAGAGCTGCCCGAACTGGTGG
GCGGCTCTGCCGACCTGACCCCGTCCAACCTGACCGACTGGTCAAACAGCGTTTCCGTTACCCGCGACAAAGGCGGCAAC
TACATCCACTACGGCGTGCGCGAGTTCGGTATGGGCGCGATTATGAACGGTTTGGTATTGCACGGCGGCGTAAAACCCTT
CGGCGCGACTTTCCTGATGTTCAGCGAATACGAGCGCAACGCCCTGCGTATGGCTGCGTTGATGAAAATCAACCCTGTAT
TTGTGTTCACCCACGATTCCATCGGTTTGGGCGAAGACGGCCCGACCCACCAGCCGATTGAGCAAACCGCCACCCTGCGC
CTGATTCCGAATATGGACGTATGGCGGCCGTGCGACACCGCCGAATCCTTGGTCGCTTGGGCAGAAGCCGTCAAAGCCGC
CGATCACCCGTCCTGCCTGATTTTCAGCCGTCAAAACCTGAAATTCCAAGCGCGCAGCGAACAACAACTGGACGACATCA
AACGCGGCGGCTACATCATCAGCGAAGCCCAAGGCAACGCCCAAGCCGTCATCATTGCCACCGGTTCCGAAGTCGAGCTG
GCTTTGGAAGCGCAAAAAGCCCTCGCCGCGCAAAACATCGCCGTGCGCGTCGTTTCCATGCCGTCCACCAACGTATTCGA
CCGCCAAGACGCCGCCTATCAAGCCACCGTCCTGCCCGAAGGTCTGCCGCGCGTTGCCGTAGAAGCCGGACACGCCGACG
GCTGGTACAAATACGTCGGTCTGAACGGCGCAGTCGTCGGCATCAACCGCTTCGGCGAATCCGCCCCTGCCGACTTACTC
TTCAAAGCATTCGGCTTTACCGTGGACAATGTGGTCGATACAGTGAAATCAGTGCTGTAA

Protein sequence :
MSQLANAIRFLSADAVQKANSGHPGAPMGMAEMAETLWTKFLNHNPANPKFYNRDRFVLSNGHASMLLYSLLHLTGYNLS
IEDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVS
HEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPQRFESYGWHVVPNVNGHDTAAIQAAIEAARAETGKPSIICC
KTLIGKGSANKEGSHKTHGAPLGADEIEATRKHLGWTYPAFEIPQEIYDAWNAKEQGAKLEADWNELFAQYQAKYPAEAA
EFVRRMDKKLPDNFDEYVQAALKEVCAKAETIATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVSVTRDKGGN
YIHYGVREFGMGAIMNGLVLHGGVKPFGATFLMFSEYERNALRMAALMKINPVFVFTHDSIGLGEDGPTHQPIEQTATLR
LIPNMDVWRPCDTAESLVAWAEAVKAADHPSCLIFSRQNLKFQARSEQQLDDIKRGGYIISEAQGNAQAVIIATGSEVEL
ALEAQKALAAQNIAVRVVSMPSTNVFDRQDAAYQATVLPEGLPRVAVEAGHADGWYKYVGLNGAVVGINRFGESAPADLL
FKAFGFTVDNVVDTVKSVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 64
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 60