Gene Information

Name : thiC (NMO_0127)
Accession : YP_003082370.1
Strain : Neisseria meningitidis alpha14
Genome accession: NC_013016
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 120162 - 122063 bp
Length : 1902 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACTACGCCAAAAAAAACCGCCAAAACTTCCGGCAACGAAGCGCGCGAACTTGCCGACTTGAGCGAAGACATCGGTAT
CCGCTTCAAATATCCGAACTCGGAACGCGTGTATCTGCAAGGCAGCCGCGACGACATCCGCGTGCCTTTGCGTGAAATCC
GTCAGGACGACACCTATACGGCGCAAGGTACGGAAGCCAATCCGCCGATTCCCGTCTATGACACCAGCGGCGTGTACGGC
GATCCGGCGGCACACATCAATTTAAAACAAGGTCTGCCGCACATCCGCACGGCGTGGCTGGACGAACGCGGCGATACCGA
AATCCTGCCCAAGCTCTCCAGCGAATACGGCATCGAACGCGCACACGATCCGAAAACCGCCCATCTGCGCTTCAACCAAA
TCACCCGCCCGCGCCGCGCCAAAGCCGGCCGCAACGTAACCCAGCTTCACTACGCGCGCCAAGGCATTATCACTCCCGAA
ATGGAGTTTGTCGCCATACGCGAACGTTTAAAATTAGACGAATTGTCCCAAAAACCGGAATACGCCAAGCTCTTGAAACA
ACACGCAGGGCAAAGTTTCGGCGCGAATATCCCGACCCATCCCGACCAAATCACGCCTGAATTCGTGCGCCGAGAAATCG
CCGCCGGACGCGCGATTATTCCCGCCAACATCAACCACCCCGAACTCGAACCGATGATTATCGGCCGCAACTTTCGTGTC
AAAATCAACGGCAACTTGGGCAACTCCGCCGTAACCTCCAGCCTGACCGAAGAAGTCGAAAAAATGGTGTGGTCGCTGCG
TTGGGGCGCGGACACGATTATGGACTTATCCACAGGCGCACACATCCACGAAACGCGCGAATGGATTATCCGCAACGCGC
CCGTCCCCATCGGCACAGTGCCTATTTATCAGGCTTTGGAAAAAACCGGCGGCATTGCCGAAGATTTGACTTGGGATTTG
TTCCGTGACACCTTAATCGAGCAGGCGGAACAAGGCGTGGACTATTTCACCATACACGCGGGCGTGTTGCTGCGTTATGT
ACCGATGACCGCCAACCGCCTCACCGGCATCGTCTCGCGCGGCGGTTCGATTATGGCGAAATGGTGTTTGGCACATCATC
GGGAAAACTTCCTCTACACGCATTTCGACGAAATCTGCGAAATTATGAAAGCGTATGACGTATCGTTCAGCCTCGGCGAC
GGCCTGCGCCCCGGCTGCATTGCCGATGCCAACGACGAATCCCAATTCGCCGAACTGCACACCTTGGGCGAATTGACCGA
TAAAGCGTGGAAACATGACGTACAAGTCATGATCGAAGGCCCCGGCCATGTGCCGCTGCAACGCGTCAAAGAAAATATGA
CCGAAGAGCTGCAACACTGTTTTGAAGCGCCGTTTTACACACTCGGCCCGCTTGTTACCGACATCGCCCCCGGCTACGAC
CACATCACCTCGGGCATAGGCGCGGCGAATATCGGCTGGTACGGCACGGCGATGCTTTGTTACGTTACCCCCAAAGAGCA
TTTGGGGCTGCCCGACAAAGAAGACGTGCGCACCGGCATCATCACCTACAAACTCGCCGCCCACGCCGCCGACCTCGCCA
AAGGCTGGCCGGGCGCACAGTTGCGCGACAACGCCCTGAGCAAGGCGCGTTTCGAGTTCCGCTGGCGCGACCAGTTCCGC
CTAAGCCTCGACCCCGAACGCGCCGAAAGCTTCCACGACGAAACCCTGCCCGCCGAAGGCGCGAAAATCGCCCACTTCTG
CTCAATGTGCGGCCCCAAATTCTGCTCGATGAAAATCACGCAGGAAGTGCGCGACTACGCCGACAAGCAAAAAGCCCAAC
GGCAGGGCATGGAGGAAAAAGCGGTCGAGTTCGTCAAAAAAGGCGCGAAGATTTACAGTTGA

Protein sequence :
MTTPKKTAKTSGNEARELADLSEDIGIRFKYPNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGVYG
DPAAHINLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPE
MEFVAIRERLKLDELSQKPEYAKLLKQHAGQSFGANIPTHPDQITPEFVRREIAAGRAIIPANINHPELEPMIIGRNFRV
KINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDL
FRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGD
GLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYD
HITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFR
LSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 99
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72