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Name : spaP (ECSP_3822) Accession : YP_003079643.1 Strain : Escherichia coli TW14359 Genome accession: NC_013008 Putative virulence/resistance : Virulence Product : surface presentation of antigens protein SpaP Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG4790 EC number : - Position : 3784128 - 3784793 bp Length : 666 bp Strand : - Note : part of a type III secretory system probably involved in invasion into eukaryotic cells DNA sequence : ATGTCAAATAGCATTTCGCTGATAGCGATACTATCATTATTTACACTATTGCCGTTTATAATAGCATCCGGGACATGTTT TATTAAATTCTCGATTGTTTTTGTTATTGTCCGAAACGCATTGGGACTTCAGCAAGTGCCATCAAATATGACACTTAATG GGGTTGCTTTGCTATTGTCAATGTTTGTAATGATGCCGGTTGGGAAGGAAATATATTATAACAGTCAGAATGAGAATCTT TCATTCAATAATGTAGCGTCGGTTGTTAATTTTGTTGAGACAGGCATGAGTGGTTATAAATCATATTTGATAAAATATTC TGAACCGGAGTTGGTTAGCTTTTTTGAAAAGATTCAGAAGGTGAATAGTTCTGAAGACAATGAAGAGATAATCGATGATG ATAATATTTCAATTTTCTCGTTACTCCCGGCATATGCGTTAAGTGAGATAAAAAGTGCATTTATTATAGGTTTTTATATC TATTTACCCTTTGTTGTAGTGGATCTGGTTATATCCAGCGTTCTGTTAACGTTAGGTATGATGATGATGAGTCCGGTAAC CATATCTACACCGATAAAATTAATTCTGTTTGTCGCGATGGACGGTTGGACAATGTTATCAAAAGGACTCATATTACAAT ATTTTGACCTATCCATTAATCCCTGA Protein sequence : MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRNALGLQQVPSNMTLNGVALLLSMFVMMPVGKEIYYNSQNENL SFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI YLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| spaP | NP_311752.1 | surface presentation of antigens protein SpaP | Not tested | LIM | Protein | 3e-67 | 100 |
| epaP | AAZ31293.1 | EpaP | Virulence | ETT2 | Protein | 3e-65 | 99 |
| spaP | NP_461811.1 | surface presentation of antigens protein SpaP | Virulence | SPI-1 | Protein | 5e-49 | 67 |
| spaP | NP_457284.1 | secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 1e-48 | 67 |
| spaP | NP_806493.1 | surface presentation of antigens protein SpaP | Virulence | SPI-1 | Protein | 1e-48 | 67 |
| spaP | YP_217809.1 | surface presentation of antigens protein SpaP | Virulence | SPI-1 | Protein | 5e-49 | 67 |
| spaP | AAS66865.1 | SpaP | Not tested | SSR-2 | Protein | 2e-48 | 59 |
| ysaR | AAS66846.1 | YsaR | Not tested | SSR-1 | Protein | 2e-41 | 57 |
| escR | AAK26700.1 | EscR | Virulence | LEE | Protein | 3e-26 | 43 |
| escR | AAL57527.1 | EscR | Virulence | LEE | Protein | 3e-26 | 43 |
| escR | YP_003223490.1 | T3SS structure protein EscR | Virulence | LEE | Protein | 4e-26 | 43 |
| escR | CAC81847.1 | EscR protein | Virulence | LEE II | Protein | 3e-26 | 43 |
| escR | YP_003232138.1 | type III secretion system protein | Virulence | LEE | Protein | 4e-26 | 43 |
| escR | CAI43889.1 | EscR protein | Virulence | LEE | Protein | 3e-26 | 43 |
| lscR | AAO18040.1 | LscR | Virulence | TTSS locus | Protein | 3e-25 | 42 |
| escR | ACU09473.1 | type III secretion system protein EscR | Virulence | LEE | Protein | 3e-26 | 42 |
| escR | YP_003236103.1 | T3SS structure protein EscR | Virulence | LEE | Protein | 4e-26 | 42 |
| escR | NP_290283.1 | type III secretion system protein | Virulence | LEE | Protein | 4e-26 | 42 |
| ECs4583 | NP_312610.1 | type III secretion system protein | Virulence | LEE | Protein | 3e-26 | 42 |
| escR | AAC38369.1 | EscR | Virulence | LEE | Protein | 1e-25 | 42 |
| escR | AAC31528.1 | L0049 | Virulence | LEE | Protein | 3e-26 | 42 |
| escR | AFO66317.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 2e-23 | 42 |
| escR | AFO66400.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 2e-23 | 42 |
| unnamed | AAL06354.1 | EscR | Virulence | LEE | Protein | 9e-25 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG0551 | Protein | 2e-49 | 67 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG2455 | Protein | 2e-47 | 62 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG1773 | Protein | 2e-48 | 62 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG1012 | Protein | 4e-43 | 59 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG0394 | Protein | 1e-26 | 45 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG0188 | Protein | 5e-27 | 44 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG0827 | Protein | 1e-26 | 42 |
| spaP | YP_003079643.1 | surface presentation of antigens protein SpaP | VFG0715 | Protein | 7e-26 | 42 |
