Gene Information

Name : dadX (ECSP_1587)
Accession : YP_003077504.1
Strain : Escherichia coli TW14359
Genome accession: NC_013008
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : -
Position : 1616044 - 1617114 bp
Length : 1071 bp
Strand : +
Note : catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA

DNA sequence :
ATGACCCGTCCGATACAGGCCAGCCTCGATCTGCAGGCATTAAAACAGAATCTGTCCATTGTCCGCCAGGCCGCGCCGCA
CGCGCGCGTCTGGTCGGTGGTAAAAGCGAACGCTTACGGGCACGGTATTGAGCGTATCTGGAGCGCGCTCGGGGCTACCG
ATGGCTTTGCATTACTTAACCTGGAAGAAGCAATAACGTTACGTGAGCGCGGCTGGAAAGGACCGATCCTGATGCTGGAA
GGATTTTTCCATGCTCAGGATCTGGAAATGTATGACCAGCACCGCCTGACCACCTGCGTACACAGCAACTGGCAGCTCAA
AGCACTGCAAAATGCGCGGCTAAAAGCACCGTTGGATATTTATCTTAAAGTGAACAGTGGGATGAATCGGTTGGGCTTCC
AGCCCGATCGCGTGCTTACCGTCTGGCAGCAGTTGCGGGCGATGGCGAATGTTGGCGAAATGACCCTGATGTCGCATTTT
GCCGAGGCGGAACATCCTGATGGAATTTCCGGCGCGATGGCGCGTATTGAGCAGGCGGCGGAAGGGCTGGAGTGTCGGCG
TTCGTTGTCCAATTCGGCGGCGACTCTGTGGCACCCAGAAGCGCATTTTGACTGGGTTCGGCCTGGCATTATTTTGTATG
GCGCTTCGCCGTCCGGTCAGTGGCGTGATATCGCCAATACTGGATTACGTCCGGTGATGACGCTAAGCAGTGAGATTATT
GGTGTCCAGACGCTAAAAGCGGGCGAGCGTGTGGGCTACGGCGGTCGTTATACTGCGCGCGATGAGCAGCGAATCGGCAT
TGTTGCCGCAGGATACGCCGACGGTTATCCGCGCCACGCGCCTACCGGTACCCCTGTTTTAGTGGACGGCGTGCGCACCA
TGACGGTGGGGACAGTCTCGATGGATATGCTGGCGGTCGATTTAACGCCTTGCCCGCAGGCGGGTATTGGTACGCCAGTT
GAGCTGTGGGGCAAGGAGATCAAAATTGATGATGTCGCCGCCGCTGCCGGAACGGTGGGCTATGAGTTGATGTGCGCGCT
GGCGTTACGCGTCCCGGTTGTGACGGTGTAA

Protein sequence :
MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIERIWSALGATDGFALLNLEEAITLRERGWKGPILMLE
GFFHAQDLEMYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
AEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII
GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPV
ELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 5e-164 99