Gene Information

Name : cah (ECSP_1319)
Accession : YP_003077239.1
Strain : Escherichia coli TW14359
Genome accession: NC_013008
Putative virulence/resistance : Virulence
Product : calcium-binding autotransporter
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3468
EC number : -
Position : 1388023 - 1390872 bp
Length : 2850 bp
Strand : +
Note : -

DNA sequence :
ATGAAACGACATCTGAACACCAGCTACAGGCTGGTATGGAATCACATTACGGGCACCCTGGTGGTGGCCTCCGAACTGGC
CCGCTCACGGGGAAAACGCGCCGGTGTGGCGGTTGCGCTGTCTCTTGCTGCTGTCACATCAGTCCCGGCACTGGCTGCTG
ACAAGGTTGTACAGGCGGGAGAAACCGTGAACGATGGAACACTGACAAATCATGACAACCAGATTGTCTTCGGTACGGCC
AACGGAATGACCATCAGTACCGGGCTGGAACTGGGGCCGGACAGTGAAGAAAACACCGGTGGGCAATGGATACAGAATGG
CGGGATAGCCGGAAACACCACTGTCACCACAAATGGTCGTCAGGTCGTGCTGGAGGGGGGAACAGCCAGTGATACGGTTA
TTCGTGACGGCGGGGGACAGAGCCTGAACGGACTGGCGGTGAACACCACACTGAATAACAGAGGCGAGCAGTGGGTGCAT
GAGGGCGGGGTTGCCACCGGTACAATTATCAACCGCGACGGTTACCAGAGCGTTAAAAGTGGCGGGCTGGCAACAGGAAC
CATCATCAACACCGGCGCAGAAGGCGGCCCTGATTCTGACAACTCGTATACGGGTCAGAAGGTCCAGGGAACAGCAGAAT
CCACCACCATCAACAAAAATGGACGGCAGATTATCTTATTTTCCGGGCTAGCCCGTGACACTCTCATTTACGCAGGTGGT
GACCAGTCGGTACACGGAAGGGCCCTGAATACCACACTGAATGGCGGTTACCAATATGTGCACAGGGACGGACTTGCGCT
GAACACGGTAATTAACGAGGGGGGCTGGCAGGTTGTTAAGGCAGGTGGCGCTGCCGGTAACACCACCATAAATCAGAACG
GTGAACTGAGGGTACATGCCGGCGGGGAAGCCACTGCAGTCACCCAGAACACGGGCGGTGCACTGGTTACCAGTACTGCT
GCAACTGTCATCGGCACAAACCGTCTGGGGAATTTCACGGTGGAAAACGGTAAGGCTGACGGTGTTGTTCTGGAATCCGG
CGGTCGTCTGGATGTACTGGAGAGCCATTCAGCACAGAATACCCTAGTGGATGACGGCGGTACCCTGGCAGTGTCTGCCG
GCGGTAAGGCGACAAGTGTCACCATAACATCCGGTGGTGCCCTGATTGCAGACAGTGGTGCCACTGTTGAGGGGACCAAT
GCCAGCGGTAAGTTCAGTATTGATGGCACATCCGGTCAGGCCAGCGGCCTGCTGCTGGAAAATGGCGGCAGCTTTACGGT
TAATGCCGGGGGACAGGCTGGCAACACCACTGTCGGACATCGTGGAACACTGACGCTGGCTGCCGGGGGAAGTCTGAGTG
GCAGAACACAGCTCAGTAAAGGCGCCAGTATGGTACTGAATGGTGATGTGGTCAGTACCGGCGATATTGTTAACGCAGGG
GAGATTCGCTTTGATAATCAGACGACACCGAATGCCGCGCTGAGCCGTGCTGTTGCAAAAAGTAACTCCCCGGTAACGTT
CCATAAACTGACCACCACGAACCTCACCGGCCAGGGCGGCACCATCAATATGCGTGTTCGCCTTGATGGCAGCAATGCCT
CTGACCAGCTGGTGATTAATGGTGGTCAGGCAACCGGCAAAACCTGGCTTGCGTTTACAAATGTCGGAAACAGCAACCTC
GGGGTGGCAACCACCGGACAGGGTATCCGGGTTGTGGATGCACAGAATGGCGCCACCACAGAAGAAGGTGCGTTTGCCCT
GAGTCGCCCGCTTCAGGCCGGCGCCTTTAACTACACCCTGAACCGTGACAGCGATGAAGACTGGTACCTGCGCAGTGAAA
ATGCTTATCGTGCTGAAGTCCCCCTGTATACATCCATGTTGACACAGGCAATGGACTATGACCGGATTCTGGCAGGCTCC
CGCAGCCATCAGACCGGTGTAAACGGTGAAAATAACAGCGTCCGTCTCAGCATTCAGGGCGGTCATCTCGGTCACGATAA
CAACGGCGGTATTGCCCGTGGAGCCACGCCGGAAAGCAGCGGCAGCTATGGCTTCGTCCGTCTGGAGGGTGACCTGCTCA
GAACAGAGGTTGCCGGTATGTCTCTGACGACAGGGGTGTATGGTGCTGCAGGCCATTCTTCCGTTGATGTTAAGGATGAT
GACGGTTCCCGCGCCGGCACGGTCCGGGATGATGCCGGCAGTCTGGGCGGATACCTGAATCTGGTACACACATCCTCCGG
CCTGTGGGCTGACATTGTGGCCCAGGGAACCCGTCACAGCATGAAAGCGTCATCGGACAATAACGACTTCCGCGCCCGGG
GCTGGGGCTGGCTGGGCTCACTGGAAACCGGTCTGCCCTTCAGTATCACTGACAATCTGATGCTGGAGCCACAACTGCAG
TACACCTGGCAGGGACTCTCCCTGGATGACGGCCAGGATAACGCCGGTTATGTGAAGTTCGGGCATGGCAGTGCACAACA
TGTGCGTGCCGGTTTCCGTCTGGGCAGCCACAACGATATGACCTTTGGTGAAGGCACCTCATCCCGTGACACCCTGCGCG
ACAGTGCAAAACACAGTGTGAGTGAACTGCCGGTGAACTGGTGGGTACAGCCTTCTGTTATCCGCACCTTCAGCTCCCGG
GGTGACATGAGCATGGGGACAGCCGCAGCCGGCAGTAACATGACGTTCTCACCGTCCCGGAATGGCACGTCACTGGACCT
GCAGGCCGGACTGGAAGCCCGTATCCGGGAAAATATCACCCTGGGCGTTCAGGCCGGTTATGCCCACAGCGTCAGCGGCA
GCAGCGCTGAAGGCTATAACGGTCAGGCTACGCTGAATATGACTTTCTGA

Protein sequence :
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAGETVNDGTLTNHDNQIVFGTA
NGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGRQVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVH
EGGVATGTIINRDGYQSVKSGGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHAGGEATAVTQNTGGALVTSTA
ATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQNTLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTN
ASGKFSIDGTSGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNL
GVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGS
RSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQ
YTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSR
GDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Z1211 NP_286746.1 adhesin Not tested TAI Protein 0.0 100
Z1651 NP_287154.1 adhesin Not tested TAI Protein 0.0 100
unnamed CAE85197.1 antigen43 protein orthologue Not tested PAI V 536 Protein 0.0 90
unnamed AAL08472.1 putative autotransporter Not tested SRL Protein 0.0 89
aec67 AAW51750.1 Aec67 Not tested AGI-3 Protein 0.0 65
S3195 NP_838479.1 outer membrane fluffing protein Not tested SHI-1 Protein 0.0 64
unnamed CAD66200.1 hypothetical protein Virulence PAI III 536 Protein 0.0 61
aidA ADD91708.1 AidA Not tested PAI-I AL862 Protein 0.0 59
sap AAK00474.1 Sap Not tested SHI-1 Protein 0.0 59
SF2991 NP_708765.1 outer membrane fluffing protein Not tested SHI-1 Protein 0.0 59
flu CAI43838.1 antigen 43 Not tested LEE Protein 0.0 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cah YP_003077239.1 calcium-binding autotransporter VFG1063 Protein 0.0 89
cah YP_003077239.1 calcium-binding autotransporter VFG1675 Protein 0.0 61
cah YP_003077239.1 calcium-binding autotransporter VFG0655 Protein 0.0 59