Gene Information

Name : kdsB (ECSP_1022)
Accession : YP_003076954.1
Strain : Escherichia coli TW14359
Genome accession: NC_013008
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1105443 - 1106189 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTGTGGTCATTATTCCCGCGCGCTACGCGTCCACGCGTCTGCCCGGTAAACCATTGGTTGATATTAACGGCAA
ACCCATGATTGTTCATGTTCTTGAACGCGCGCGCGAATCAGGTGCCGAGCGCATCATCGTGGCAACCGATCATGAGGATG
TCGCCCGCGCCGTTGAAGCCGCTGGCGGTGAAGTATGTATGACGCGCGCCGATCACCAGTCAGGGACAGAACGCTTGGCG
GAAGTTGTCGAAAAATGCGCGTTCAGCGACGACACGGTGATCGTTAATGTGCAGGGTGATGAACCGATGATCCCTGCGAC
AATCATTCGTCAGGTTGCTGATAACCTCGCTCAGCGTCAGGTGGGTATGGCGACTCTGGCGGTGCCAATCCACAATGCGG
AAGAAGCGTTTAACCCGAATGCGGTGAAAGTGGTTCTCGACGCTGAAGGGTATGCACTGTACTTCTCACGCGCTACCATT
CCGTGGGATCGTGATCGTTTTGCAAAAGGCCTTGAAACCGTTGGCGATAACTTCCTGCGTCATCTTGGTATTTATGGCTA
CCGTGCAGGCTTTATCCGTCGTTACGTCACCTGGCAGCCAAGCCCGTTAGAACACATCGAAATGTTAGAGCAGCTTCGTG
TTTTGTGGTACGGCGAAAAAATCCATGTTGCTGTCGCGCATGAAGTTCCTGGCACAGGTGTGGATACCCCTGAAGATCTC
GAGCGCGTTCGCGCTGAAATGCGCTAA

Protein sequence :
MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKGLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYGEKIHVAVAHEVPGTGVDTPEDL
ERVRAEMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-34 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-34 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-34 45