Gene Information

Name : guaA (TERTU_2615)
Accession : YP_003074028.1
Strain : Teredinibacter turnerae T7901
Genome accession: NC_012997
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2888184 - 2889761 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGAATATTCATTCTCAGCGAGTCCTTATTCTTGACTTTGGATCGCAGTACACCCAGTTAATTGCTCGTCGAAT
TCGCGAGGTGGGTGTTTTTTCTGAAATTCGCGCATTTGATATGACCGATGAGGAAATTCGGGAGTACAACCCGAAAGCCA
TTATTCTCTCGGGCGGCCCGGAGTCGGTAACGGCTGGCGCCTCACCGCGCGCGCCGGAAGCCGTATTTGAATTGGGTGTG
CCAGTACTGGGTATCTGTTACGGAATGCAGACTATGGCAGAGCAGCTGGGGGGCAGGGTGCAATCCTCGGAGGTGCGGGA
ATTCGGTTATGCGCAGGTGCGGGTTGCTGGTGAAAGTGCGCTTTTCCGCGATATTAAAGATCATGTCGACAGTGACGGCG
GCGCTTTGTTGGATGTCTGGATGAGCCATGGCGACAAAGTCATTGCCATGCCGGACACGTTCAGCCTGCTGGCCTCAACA
CCTTCCTGTCCCATCGCTGGGATGAGCTGGGAAGAGAAGCGATTTTATGGCGTTCAGTTCCATCCGGAGGTTACTCACAC
GTTGCAAGGCAAGCGTATTTTCGAGCATTTTGTCTTGGAGATTGCCGGCTGTGAACCTCTTTGGACTCCTGCAAATATCG
TGGAAGACGCTATCGAACGCGTGCGCGAGAAAGTGGGATCAGACAAGGTTTTACTTGGTTTGTCCGGTGGCGTGGATTCC
TCAGTGGTAGCCGCACTTTTGCATCGCGCGATTGGTGACCAGCTGACGTGCGTGTTCGTCGACAACGGGTTGCTGCGAAA
GCAGGAAGGTGACCAGGTGATGGACATGTTTGCCAAGAACATGGGGGTGAAAGTTGTCCGCGCGGATGCTGAAGACCTGT
TCCTTTCCAAGCTGCATGGGATAAACGATCCGGAGCAGAAGCGAAAAATAATCGGCAACACTTTTATCGAAGTGTTCGAT
ACAGAGGCGGCCAAATTGCAAAACGTGAAATGGCTTGCGCAGGGCACCATTTATCCGGATGTTATTGAGTCCGCTGCATC
CAAAACAGGCAAAGCGCATGTTATCAAGTCCCATCACAATGTGGGTGGCTTGCCAGAAGACATGCAGTTTGAGCTTGTTG
AGCCTTTGCGCGAACTGTTCAAAGACGAGGTGCGCAAAATTGGCCTGGAATTGGGCTTGCCTTACGATATGGTCTACCGC
CATCCGTTCCCGGGCCCTGGCCTTGGTGTGCGTATCCTTGGTGAAGTTAAAAAGGAATATGCGGATATTTTGCGAGAAGC
TGATGCCATCTTTATCGAAGAGTTGCGAAATGCTGATTGGTACCATAAAACCAGCCAGGCTTTTGCGGTATTCCTCCCCG
TGAAGTCAGTTGGTGTTGTTGGCGATGCACGACGTTACGAATGGGTTATCTCGCTACGTGCCGTTGAAACAGTAGATTTT
ATGACCGCGCGCTGGGCTCACTTGCCCTACGACTTGTTAGAGAAGGTTTCCAATCGAATCATCAACGAGATTTCCGGTGT
GTCGCGTGTGGCTTATGACGTATCGAGCAAGCCTCCTGCGACGATTGAGTGGGAATAA

Protein sequence :
MTQNIHSQRVLILDFGSQYTQLIARRIREVGVFSEIRAFDMTDEEIREYNPKAIILSGGPESVTAGASPRAPEAVFELGV
PVLGICYGMQTMAEQLGGRVQSSEVREFGYAQVRVAGESALFRDIKDHVDSDGGALLDVWMSHGDKVIAMPDTFSLLAST
PSCPIAGMSWEEKRFYGVQFHPEVTHTLQGKRIFEHFVLEIAGCEPLWTPANIVEDAIERVREKVGSDKVLLGLSGGVDS
SVVAALLHRAIGDQLTCVFVDNGLLRKQEGDQVMDMFAKNMGVKVVRADAEDLFLSKLHGINDPEQKRKIIGNTFIEVFD
TEAAKLQNVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPEDMQFELVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADILREADAIFIEELRNADWYHKTSQAFAVFLPVKSVGVVGDARRYEWVISLRAVETVDF
MTARWAHLPYDLLEKVSNRIINEISGVSRVAYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-130 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-131 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-131 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-118 51