Gene Information

Name : arsB (p2METDI0027)
Accession : YP_003071373.1
Strain :
Genome accession: NC_012989
Putative virulence/resistance : Resistance
Product : arsenical pump (Ars family)
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 26456 - 27751 bp
Length : 1296 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15004242, 1535622, 7721697, 95355341; Product type t : transporter

DNA sequence :
ATGCTCGCGCTTGCCATTTTCCTCGTCACCCTCGTTCTCGTCATCTGGCAGCCCAAGGGTCTCGGGATCGGGTGGAGCGC
CCTGGCCGGCGCGGCCGTCGCCCTCGCCACGGGGGTGATCCATCCCGGCGATATTCCGGTGGTCTGGCATATCGTCTGGG
ACGCCACGTTCACGTTCGTGGCGCTGATCATCATCTCGCTGCTGCTCGATGAGGCCGGGTTCTTCCACTGGGCGGCCCTG
CACATCGCCCGCTGGGGCGGCGGCCGGGGCCGGCTGCTCTTTCCGCTGGTGATCCTGCTTGGGGCCGCCATCGCGGCGGT
GTTCGCCAACGACGGCGCGGCGCTGCTGCTGACCCCCATCGTCCTGGCGATCCTGCTGCGCCTCAAGTTCCCCCCGGCGG
CAGCGCTGGCGTTCATCGTCGCCTGCGGGTTCGTGGCCGACTCGACCTCCCTGCCGCTGGTGATCTCCAACCTCGTGAAC
ATCGTCTCGGCCAACTACTTCGACGTGACGTTCGGGCGCTACGCCGCCGTGATGGTGCCGGTGAACCTGGTCTCGCTCCT
CGCCACGCTGGTGGTGCTGTGGGCGTATTTCCGGCACGACGTGCCGGCGACCTACCCGGTCGGCGAGCTGGAACCGCCTC
GAGACGCGATCCGCGATCCGGTGGTGTTCAAGGCGGCCTTTCCGCTGCTCGGCGTGCTGCTGCTCGCCTACTTCATCACC
GCGCCGTTCGGCGTGCCGGTCTCGGTCGTCACCTGTGCCGGCGCGGCGGTGCTGCTCGGCCTGGCGCTGCGCGGGCGGGT
CATTCCGATCCGCAAGGTGCTGACCGGCGCGCCCTGGCAGATCGTGCTGTTCAGCCTCGGCATGTACCTCGTGGTCTACG
GGCTCAGGAACGCCGGCCTGACCGACGAGCTGGCCAAGGGCCTGGTCTGGTTGGGCGGGCAGGGGCCGTGGGTTGCCACT
GTCGGCACCGGTTTTGCGGCGGCCATCCTGTCCTCGGTGATGAACAACATGCCGAGCGTGCTGATCGGAGCGCTGTCGAT
CCAGCAGGCCCCGGATCTCACACCTTTGACCCGCGAGCTAATGGTCTACGCCAACGTGATCGGCTGCGATCTCGGCCCGA
AGTTCACGCCGATCGGCAGCCTGGCGACCCTGCTCTGGCTGCACGTGCTGGCCAGCAAGGGCCAGCGCATCACGTGGGGC
CAGTACATGAAGGTCGGCCTGGTCATCACGCCGCCGGTGCTGCTGGTCTCGCTGCTGGCGCTGGCGGCCTGGCTGCCCGT
GCTCGGGACGCAGTAG

Protein sequence :
MLALAIFLVTLVLVIWQPKGLGIGWSALAGAAVALATGVIHPGDIPVVWHIVWDATFTFVALIIISLLLDEAGFFHWAAL
HIARWGGGRGRLLFPLVILLGAAIAAVFANDGAALLLTPIVLAILLRLKFPPAAALAFIVACGFVADSTSLPLVISNLVN
IVSANYFDVTFGRYAAVMVPVNLVSLLATLVVLWAYFRHDVPATYPVGELEPPRDAIRDPVVFKAAFPLLGVLLLAYFIT
APFGVPVSVVTCAGAAVLLGLALRGRVIPIRKVLTGAPWQIVLFSLGMYLVVYGLRNAGLTDELAKGLVWLGGQGPWVAT
VGTGFAAAILSSVMNNMPSVLIGALSIQQAPDLTPLTRELMVYANVIGCDLGPKFTPIGSLATLLWLHVLASKGQRITWG
QYMKVGLVITPPVLLVSLLALAAWLPVLGTQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 1e-100 62
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 8e-80 53
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 7e-82 53
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-81 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_003071373.1 arsenical pump (Ars family) BAC0031 Protein 9e-98 63
arsB YP_003071373.1 arsenical pump (Ars family) BAC0576 Protein 6e-100 62
arsB YP_003071373.1 arsenical pump (Ars family) BAC0578 Protein 2e-100 62
arsB YP_003071373.1 arsenical pump (Ars family) BAC0577 Protein 1e-96 61
arsB YP_003071373.1 arsenical pump (Ars family) BAC0575 Protein 4e-82 53
arsB YP_003071373.1 arsenical pump (Ars family) BAC0574 Protein 2e-80 53