Gene Information

Name : METDI0978 (METDI0978)
Accession : YP_003066619.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Resistance
Product : D-alanyl-D-alanine dipeptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2173
EC number : 3.4.13.-
Position : 897735 - 898397 bp
Length : 663 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 9687406, 9736537; Product type e : enzyme

DNA sequence :
ATGCGCGTCGCACTGACGGGCCTCGCCCTCGCCGCGTCCCAGCCGGCCGCGGCGGAAGCCGATCCCTTCGTCGATGCCGC
CCGGCACGTGCCGGGGCTCGCGCTCGACATGCGCTATGCCGGCTCCGACAACTTCGTCGGCCGGCCCATCGCCGGCTACG
AGGCACCGCGCTGCCTGCTCACCCCGCAGGCCGCCCGCGCGCTGGCCCGGGTGCAGGCATCGCTGGCGCCGGACGGCCTC
GGCCTGAAAGTGTTCGACTGCTACCGCCCGCGCCAGGCGGTGGCCGACTTCGCCGCCTGGGCGCGCGACCCGGCCGACAC
ACGCATGAAGGCGGCCTACTACCCGCGGACGGACAAGGCGGATCTGTTCCGCCTCGGCTACATCGCCGAGCGCTCGTCGC
ATTCCCGCGGCTCCACCGTGGACCTGACGCTGGTGCGAAGCGCCGACGGCGCCGAACTCGACATGGGCACGCCGTTCGAC
CTGTTCGACCCGGCCTCGGCGACAGATTTCCCCGGCGTCAGCCGGATCCAGTCGCGCAACCGTCATCGCCTGCGCGACGC
GATGATTCGCGCCGGCTTCGTGCCCTACGCGCAGGAATGGTGGCACTTCACCCTCAAGGGCGAGCCTTACCCCGACACGG
CCTTCGGCCGGCCCGTCCGCTGA

Protein sequence :
MRVALTGLALAASQPAAAEADPFVDAARHVPGLALDMRYAGSDNFVGRPIAGYEAPRCLLTPQAARALARVQASLAPDGL
GLKVFDCYRPRQAVADFAAWARDPADTRMKAAYYPRTDKADLFRLGYIAERSSHSRGSTVDLTLVRSADGAELDMGTPFD
LFDPASATDFPGVSRIQSRNRHRLRDAMIRAGFVPYAQEWWHFTLKGEPYPDTAFGRPVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanXB YP_008394260.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 3e-32 44
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 7e-33 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase U82965.2.orf32.gene. Protein 3e-36 46
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase FJ349556.1.orf5.gene Protein 5e-35 45
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase U35369.1.gene7.p01 Protein 4e-33 44
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase AF310956.2.orf6.gene Protein 1e-32 44
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase AE016830.1.gene2249. Protein 3e-33 44
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase NC_005054.2598281.p0 Protein 1e-36 43
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase M97297.gene.p01 Protein 1e-36 43
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase NC_014475.1.orf4.gen Protein 1e-36 43
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase AF130997.1.orf5.gene Protein 3e-31 43
METDI0978 YP_003066619.1 D-alanyl-D-alanine dipeptidase AF155139.2.orf6.gene Protein 4e-32 43