Gene Information

Name : hemC (METDI5906)
Accession : YP_003071308.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Unknown
Product : Porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 5901991 - 5902875 bp
Length : 885 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11872720, 7784514; Product type e : enzyme

DNA sequence :
ATGGCGCTGGCCCAGACCGGCATGGTCCGCGACCGGATCGTCGCGGCCAATCCGGGATTGGAGACGGAAATCGTCGTCGT
CTCGACCGTGGCTGACCGCGTGCTCGATCGGCCGCTCTCCGAGATCGGCGGCAAGGGCCTGTTTACCAAGGAACTCGAAC
AGGCGCTGTTTGCCGACGAGATCGATGTCGCCGTTCACTCGATGAAGGACGTGGAGACCTGGCTGCCCGACGGGCTTGCC
ATCGCTTGCATCCTCGAACGCGACGACCCGCGCGACGCCTTCCTCAGCGCGAACGGGGCCAACGGCTTGGCCGACCTGCC
CCCCGGTGCCCGGGTCGGCACCTCCTCGCTCAGGCGAGGGGCGCAGGTGCTGATGCACCGGCCCGATCTCACCATCGTGC
CCCTGCGCGGCAATGCCAATACCCGGATGCGCAAGCTGGAGGCGGGGGAGTGCGACGCCACGCTGCTGGCGCTCGCCGGC
CTGCAGCGCCTCGGGATGGCCAATGTCGCCCGCAGCGTGCTGTCGGTGGAAGAGATGCTCCCGGCCGTGGCGCAGGGCGC
ACTCGGCATCGAGTGCCGGGCCGGCGACGACGCGATCCGGGCGCTGCTGGCGCCGGTTGCCTGCGCCACCACGACGACGG
CGCTCGACGCGGAACGCGGGCTGCTTGCCGAACTCGACGGCTCCTGCCGCACCCCCATCGCGGCGCTTGCGCAGGTGAGC
GGGGATCGCATCAGCCTCGACGGGTTGCTGTTCCTGCCGGATGGCAGCCGCCACTGGGCGGTCCATCGTGAGGGACTGGC
CGCTGACGCGGACGCGATCGGCCGCGATGCCGGGGCCGAGCTGAAGCGGGCGGCGGGCGACGTCTACTTCGCCCACCTCA
AGTAG

Protein sequence :
MALAQTGMVRDRIVAANPGLETEIVVVSTVADRVLDRPLSEIGGKGLFTKELEQALFADEIDVAVHSMKDVETWLPDGLA
IACILERDDPRDAFLSANGANGLADLPPGARVGTSSLRRGAQVLMHRPDLTIVPLRGNANTRMRKLEAGECDATLLALAG
LQRLGMANVARSVLSVEEMLPAVAQGALGIECRAGDDAIRALLAPVACATTTTALDAERGLLAELDGSCRTPIAALAQVS
GDRISLDGLLFLPDGSRHWAVHREGLAADADAIGRDAGAELKRAAGDVYFAHLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-50 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-50 50