Gene Information

Name : tkt (METDI5538)
Accession : YP_003070954.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 5502850 - 5504925 bp
Length : 2076 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15752350, 8396116; Product type e : enzyme

DNA sequence :
ATGAGCGGTGCAGACACGAGCCCGAAGGCGGCCCTGAGCCAGGGCGACAAGCTCGCGATCGACACGATCCGGACGCTCGC
GATCGACGCGGTGCAGAAGGCCAATTCCGGACATGCCGGCGCACCGATGGCGCTGGCGCCCGTCGCCTACACCCTGTGGA
ACCGGTATCTGCGCTACGATCCGGCCCATCCGCATTGGCCGAACCGCGACCGCTTCGTGCTCTCGGCGGGTCACGCCTCG
ATGCTGCTCTACGGGCTGCTGCACTTGGCCCGCGTGGCCGAGAAGGACGGCGGCAATTCCCCCGCCATCTCGCTGGACGA
CATCAAGAAATTCCGGCAGCTCGACAGCCGCACGCCGGGCCATCCGGAATACCACTTCACCACCGGCGTCGAGACCACCA
CCGGGCCGCTGGGCCAGGGCGTGGCGAATTCCGTCGGCATGGCGATGGGCGGCCGCTTCAAGGGCGAGCGCATGAACCGG
CCCGACCTGCCGCTGTTCGACTACAACGTCTACGCCATCTGCTCGGATGGCGACCTGATGGAGGGCGTCAGCCAGGAGGC
CGCCTCGATCGCCGGGCACCTGCGCCTGTCGAACCTCTGCTGGATCTACGACAACAACACCATCACCATCGAGGGCCACA
CCGAACTCGCCTTCTCGGAAGAGGTCGCCGCGCGCTTCCTCGCCTATGGCTGGCAGGTTCTGCGGGTGGCCGATGCCAAC
GACACCCATGCCATCGCCTCGGCGCTCGAGACCTTCCTGCAATCGAGCGACCGCCCGACCCTGATCATCGTCAACTCGAT
CATCGGCTACGGTGCACCGACCAAGCAGAACACGTCGAAGGCCCATTCCGACGCGCTCGGCCCCGACGAGGTGAAGGGCG
CCAAGCGCGCCTATGGCTGGCCGGAGGATTCCGAGTTCCTCGTGCCCGACGGCGTCTACGACACCTTCGCCGACGGCATC
GGCAAGCGCGGCGCCGCGCTCTACAGTCAGTGGCAGGGCTTCTTCGAGGCCGCCAAGGCGGCGGATGCGGAGCATGCCGA
GGAACTGTCGGCCTTCCTCGAAGGCCGTCTGCCGGAGGGCTGGGACCGCGACATCCCGGTCTTCGAGGCCGACGCCAAGG
GGCTCGCGACGCGCGAATCCTCGGGCAAGGTGCTCAACGCCATCGCCCAGCACGTGCCGTTCCTGCTCGGCGGCTCAGCC
GATCTGGCGCCGTCCAACAAGTCGAACCTCACTTTCGAGGGCGCGGGCTCGCTGACCCCGTTCGAGCCGGGCGGGCGCAA
CATCCATTTCGGCGTGCGTGAGCATGCCATGGGCTCGATCGTGAACGGGCTCGGGCTCGTGGGCCTGCGCGCCTACGGCG
CGACCTTCCTCGTCTTCGCCGACTACATGCGCCCGCCGATCCGGCTCGCCTCGCTGATGGAGCTGCCGGTCTTCCATATC
TTCACCCACGACTCGATCGGCGTGGGCGAGGACGGGCCGACCCACCAGCCGGTGGAGCAGATCCTCTCGCTGCGCTGCAT
CCCCGGCCTCCTGACCCTGCGCCCGGCCGACGCCAACGAGGTGGCCGAGGCCTACCGGGTGATCTTCTCGCTGAAGGATC
AGCCCGCGGTGCTGGCCCTGTCGCGCCAGCCGCTGCCGACCTTCGACCGCTCGAAATACGCCCCCGCCTCCGGCACCGCG
AAGGGTGCCTACGTGCTCGCCGATAGCGAGGGAACGCCGGACGTGATCCTGATCGGAACGGGCTCCGAGGTGCAGCTCTG
CGTCGGCGCCTACGAGACCCTGAAGGGCGAGGGCGTGAAGGCCCGCGTCGTCTCGATTCCGTCCTGGGAGCTGTTCGAGC
GCCAGGACGAGGCCTACCGCAACAGCGTCCTGCCGCCGGAGGTTCTGGCGCGCGTGGCGGTGGAGCAGGGCAGCGTCATC
GGCTGGGACCGCTACGCCGGCTCCTCGGGCTCGATCGTCGGCATGCACACCTTCGGCGCCTCGGCTCCGATCAAGGATCT
GCTCGGCAAGTTCGGCTTCACCGCCGAGAAGGTGATCGAAGCGGCCCGCGCGCAGGCGGCCAAGCACAAGAAGTAG

Protein sequence :
MSGADTSPKAALSQGDKLAIDTIRTLAIDAVQKANSGHAGAPMALAPVAYTLWNRYLRYDPAHPHWPNRDRFVLSAGHAS
MLLYGLLHLARVAEKDGGNSPAISLDDIKKFRQLDSRTPGHPEYHFTTGVETTTGPLGQGVANSVGMAMGGRFKGERMNR
PDLPLFDYNVYAICSDGDLMEGVSQEAASIAGHLRLSNLCWIYDNNTITIEGHTELAFSEEVAARFLAYGWQVLRVADAN
DTHAIASALETFLQSSDRPTLIIVNSIIGYGAPTKQNTSKAHSDALGPDEVKGAKRAYGWPEDSEFLVPDGVYDTFADGI
GKRGAALYSQWQGFFEAAKAADAEHAEELSAFLEGRLPEGWDRDIPVFEADAKGLATRESSGKVLNAIAQHVPFLLGGSA
DLAPSNKSNLTFEGAGSLTPFEPGGRNIHFGVREHAMGSIVNGLGLVGLRAYGATFLVFADYMRPPIRLASLMELPVFHI
FTHDSIGVGEDGPTHQPVEQILSLRCIPGLLTLRPADANEVAEAYRVIFSLKDQPAVLALSRQPLPTFDRSKYAPASGTA
KGAYVLADSEGTPDVILIGTGSEVQLCVGAYETLKGEGVKARVVSIPSWELFERQDEAYRNSVLPPEVLARVAVEQGSVI
GWDRYAGSSGSIVGMHTFGASAPIKDLLGKFGFTAEKVIEAARAQAAKHKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-130 45
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-133 45