Gene Information

Name : arsH (METDI4847)
Accession : YP_003070279.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Resistance
Product : NADPH-dependent FMN reductase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0431
EC number : -
Position : 4738043 - 4738810 bp
Length : 768 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10788346; Product type e : enzyme

DNA sequence : 
GTGGACAAGCCCCATCAGCCGTTCGCCGACGGGTTGCCGAACCTCTCCGAGGCGCATGTCGAACTGCCCACCGCTGAGCG
GGTGCAGGCGTCGACGCCGCTCGCGCACGCGCCGCGCTTCCTGATCCTCTACGGCTCGCTGCGAGAGCGGTCCTTCAGCC
GGTTCCTGGCCTACGAGGCGGCCCGGCTGCTGGAGGCGATGGGCGGAGAGGTGCGGATCTTCCACGCGCACGGCCTGCCG
CTCCCCGACGACGCGACGGCCGACCACCCGAAGGTGCGGGAGCTCCGCGAACTCTCGGTCTGGTCCGAGGGGCAGGTCTG
GGTGAGCCCCGAGCGGCACGGCAACCTGACCGGGGTGATGAAAAGCCAGATCGATTGGCTGCCGCTGAGCGAGGGCTCGG
TCCGCCCGACGCAGGGGCGCACGCTCGCGGTGATGCAGGTGTCGGGCGGTTCGCAGAGCTTCAATGCGGTGAACAGCATG
CGGGTGCTCGGGCGCTGGATGCGGATGATCACCATCCCGAACCAGTCCTCGGTGCCGATGGCCTACAAGGAGTTCGACGA
GGCTGGCCGCATGAGGCCAGGGCCGCTCTACGACCGGGTCGTGGACGTGTGCGAGGAGCTGATGAAGTTCACGCTCCTGA
CCCGCGGGCGGGCCGATTACCTCGTCGACCGCTACTCCGAGCGCAAGGAGCGTGAGCCCGACCGGCTCAAGGCGATTGCC
GCCGATGTGGGCTTTGTCCGGGCGCCATCCGCCGAGCGGGCATCGTAG

Protein sequence : 
MDKPHQPFADGLPNLSEAHVELPTAERVQASTPLAHAPRFLILYGSLRERSFSRFLAYEAARLLEAMGGEVRIFHAHGLP
LPDDATADHPKVRELRELSVWSEGQVWVSPERHGNLTGVMKSQIDWLPLSEGSVRPTQGRTLAVMQVSGGSQSFNAVNSM
RVLGRWMRMITIPNQSSVPMAYKEFDEAGRMRPGPLYDRVVDVCEELMKFTLLTRGRADYLVDRYSERKEREPDRLKAIA
ADVGFVRAPSAERAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsH YP_001007636.1 putative arsenic resistance protein Not tested YAPI Protein 8e-72 76
BCAM0236 YP_002232867.1 putative NADPH-dependent FMN reductase Not tested BcenGI11 Protein 2e-76 71
arsH AFC76432.1 ArsH Not tested AbaR5 Protein 2e-71 63
arsH CAJ77015.1 arsenic resistance protein Not tested AbaR1 Protein 1e-71 63
arsH ADZ05766.1 arsenic resistance protein Not tested AbaR11 Protein 1e-71 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsH YP_003070279.1 NADPH-dependent FMN reductase BAC0595 Protein 2e-63 67
arsH YP_003070279.1 NADPH-dependent FMN reductase BAC0034 Protein 8e-71 65