Gene Information

Name : ureC (METDI4405)
Accession : YP_003069865.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 4322308 - 4324023 bp
Length : 1716 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 16199586, 9150240, 9384377; Product type e : enzyme

DNA sequence :
ATGGTGCAATCACTGCCCCGGCGCCACTACCTCGAACTCTACGGTCCGACGCTTGGGGATCGCGTCCGGCTGGGCGATAC
CGCGCTGTGGGCGCAGGTCGAGGCCGACCTCACGCATTACGGCGACGAACTCGTGTTCGGCGCGGGCAAGACCATGCGGG
TCGGCACCGGCTGCGACGGCGCGCTGACCGCCGCCGACGGCATCCTCGACCTCGTCATCACCAATGCACTGATCATCGAC
GCCGTCGCCGGGGTGATCAAGGCCGATATCGGGATCAAGGACGGCCGGATCGTCGGCATCGGCAAGGCCGGTGATCCGCG
CATCATGGACGGCGTCTCGCCGGATCTGATCGTCGGTGTGAACACCGACGTACGGGCGGCCGAGGGGCTGATCGTGACGG
CGGGCGGGATCGATTGCCACGTCCACTTCATCGATCCCGGCCAGTGCCAGGAGGCGCTGTCGGCCGGCGTGACGACGTTG
ATGGGCGGCGGGCTCGGCCCGACAACGGTGCCCATCGCTTCGACGGGGACCGTCAATCTCGGGCTGATGCTCCAGGCTTC
CGAAGCCTTTCCCCTGAATTTCGGTTTCTTCGGCAAGGCGGCCTCCGACACCGCCGCGCCGCTGCTCGAGCAGCTCGCGG
CGGGAGCGGCGGGCCTCAAGATCCACGAAGACTGGGGCGCGACGACCGCAGCCATCGGCAGCGCCCTTGAGGCTGCCGAC
CGGGGCCATGCGCAGATCCAACTCCACACCGACACCCTCAACGAGTTCGGCTTCCTCGAAGACAGCCTCGAAGCCATCGC
GGGGCGGACCATCCACGCCTACCACGTCGAAGGTGCGGGTGGCGGCCACGCACCGGATATCATCCGCGTCTGCTCGCATC
CGAACGTGCTGCCCTCCTCGACCAACCCGACGAACCCGTTCACCGTCAATACGTTCGATGAACACTTCGACATGGCTATG
ACTAGCCACCACCTGAACCCACGGGTGGCAGAGGATGTGGCCTTCGCCGAATCTCGGATCCGGAAGGAGACGATCGGCGC
GGAGGACATCCTCCACGACATCGGCGCCATCAGCGCGCTCGGCTCGGACTCGCAGGGCATGGGCCGCATCGGCGAGACGA
TCGCCCGGACATGGCAGCTCGCCTCGATCATGCGGCAGACGCGCGGTCCCCTGCCCGAGGACATGGGAAGCGGCAACGAT
AACCTGAGGATCAAGCGCTACATCGCCAAGTACACCATCAACCCAGCCAAGATCTTCGGCATCGATCACGAGATCGGCTC
GATCGAGCGCGGCAAGCTCGCCGATCTGGTCTTCTGGAAGCCGGCGCTGTTCGGCGTGAAGCCCGAGCTGGTTCTCAAAT
CCGGCTTTCCGGCCTGGGCGGTGACGGGCGAGGCGAACGCCTCCTTGATGGTGTGCGAGCCGCTGCTCTACCGGCCGCAA
TGGGGAAGCTTCGGCCGCGCGGCGCGAAGCCTCTCCGTCCGGTTCATCAGCCCACTGGCGCTGGAGGCGGATCTGCCGCG
ACGCCTCGGGCTCGAATCCCGATGCGTCGCAACGCGCTCGACCCGCGGCCTGACCAAGCACGACATGGTCCTTAACGACG
CGCTTCCCGACATCGCGGTCGATGCGGACACCTACCGCGTCTCCATCGACGGCGAAGCCTGCCTATCCGCGCCCGTCGGG
ACCGTCCCCCTCGGCTCCCTCTACATGATGAAATGA

Protein sequence :
MVQSLPRRHYLELYGPTLGDRVRLGDTALWAQVEADLTHYGDELVFGAGKTMRVGTGCDGALTAADGILDLVITNALIID
AVAGVIKADIGIKDGRIVGIGKAGDPRIMDGVSPDLIVGVNTDVRAAEGLIVTAGGIDCHVHFIDPGQCQEALSAGVTTL
MGGGLGPTTVPIASTGTVNLGLMLQASEAFPLNFGFFGKAASDTAAPLLEQLAAGAAGLKIHEDWGATTAAIGSALEAAD
RGHAQIQLHTDTLNEFGFLEDSLEAIAGRTIHAYHVEGAGGGHAPDIIRVCSHPNVLPSSTNPTNPFTVNTFDEHFDMAM
TSHHLNPRVAEDVAFAESRIRKETIGAEDILHDIGAISALGSDSQGMGRIGETIARTWQLASIMRQTRGPLPEDMGSGND
NLRIKRYIAKYTINPAKIFGIDHEIGSIERGKLADLVFWKPALFGVKPELVLKSGFPAWAVTGEANASLMVCEPLLYRPQ
WGSFGRAARSLSVRFISPLALEADLPRRLGLESRCVATRSTRGLTKHDMVLNDALPDIAVDADTYRVSIDGEACLSAPVG
TVPLGSLYMMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-119 55
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-119 55
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-119 52
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-119 52
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-119 52
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-119 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_003069865.1 urease subunit alpha VFG0270 Protein 5e-113 52