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Name : aldA (METDI4227) Accession : YP_003069697.1 Strain : Methylobacterium extorquens DM4 Genome accession: NC_012988 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase, chloroacetaldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.22 Position : 4163777 - 4165300 bp Length : 1524 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15188393, 16926146, 9511738; Product type e : enzyme DNA sequence : ATGAACAAGCCCGAATTCCTGGCGGATGCCAAGACGAAGTCGCCGTTTTCGGCGCGCTACGACAACTTCATCGGCGGCCA GTGGGTCGCGCCGGCGAGCGGCCGCTACTTCGAGAACACCTCCCCCATCACCGGCAAGGTGATCTGCGAGGTCGCCCGCT CCGAGGCGGCGGACATCGAGCGGGCGCTCGACGCCGCGCACGCCGCCAAGGATGCCTGGGGCCGCACCGCGCCGGCCGAG CGCGCCCGCATCCTCAACAAGATCGCCGACCGGATGGAGGACAACCTCGATCTGATCGCGCTGGCCGAGACCTGGGACAA CGGCAAGCCGATCCGCGAGACCACCGCCGCCGACATCCCGCTCGCCATCGACCACTGGCGCTACTTCGCGAGCTGCGTCC GCGCCCAGGAAGGCGCGATCTCCGAGATCGACCACGACACGGTGGCCTACCATTTCCACGAGCCGCTCGGCGTCGTCGGC CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGGTGTGGAAGCTGGCTCCTGCGATCGCCGCCGGCAACTGTGTGGT GCTCAAGCCCGCCGAGCAGACCCCCGCCTCGATCCTCGTGGTGATGGAGCTGATCGGCGACCTGCTGCCGCCCGGCGTCA TCAACGTCGTCAACGGCTTCGGCCTGGAGGCCGGCAAGCCGCTCGCCTCGAACCCGCGCATCGCCAAGATCGCGTTCACC GGTGAGACGACCACCGGCCGCCTCATCATGCAGTACGCCTCGCAGAACCTGATCCCGGTGACGCTGGAGCTCGGCGGCAA GTCGCCGAACATCTTCTTCGGGGATGTCGTCAATGAGGACGACGACTTCTTCGACAAGGCGCTCGAAGGCTTCACCATGT TCGCCCTCAACCAGGGCGAAGTCTGCACCTGCCCGAGCCGCGCGCTCGTGCACGAGTCGATCTACGACCGCTTCATCGAG CGCGCGATCAAGCGCGTCGAGGCGATCACCCAGGGCTCGCCGCTCGATCCGGCGACGATGATCGGCGCGCAGGCGTCTTC GGAGCAGCTCGAGAAGATTCTCAGCTACGTCGATATCGGCCGCCAGGAAGGCGCCGAGTGCCTCACGGGCGGCGCCCGCG GCACCCGCGAGGGCGATCTGGCCGACGGCTTCTACATGCAGCCGACGGTGTTCAAGGGCCACAACAAGATGCGGATCTTC CAGGAGGAGATCTTCGGGCCCGTCCTCTCGGTCACGACCTTCAAGGACGACGAGGAGGCGCTCTCCATCGCCAACGACAC GCTCTACGGCCTCGGCGCCGGCGTGTGGACCCGCGACGGAACCCGCGCCTACCGCTTCGGCCGCGCCATCCAGGCCGGCC GCGTCTGGACGAACTGCTACCACGCCTACCCGGCGCACGCGGCCTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGTGAG ACCCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACATGCTGGTCAGCTACTCCTCGAAGAAGCTCGGGTTCTT CTAA Protein sequence : MNKPEFLADAKTKSPFSARYDNFIGGQWVAPASGRYFENTSPITGKVICEVARSEAADIERALDAAHAAKDAWGRTAPAE RARILNKIADRMEDNLDLIALAETWDNGKPIRETTAADIPLAIDHWRYFASCVRAQEGAISEIDHDTVAYHFHEPLGVVG QIIPWNFPILMAVWKLAPAIAAGNCVVLKPAEQTPASILVVMELIGDLLPPGVINVVNGFGLEAGKPLASNPRIAKIAFT GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFGDVVNEDDDFFDKALEGFTMFALNQGEVCTCPSRALVHESIYDRFIE RAIKRVEAITQGSPLDPATMIGAQASSEQLEKILSYVDIGRQEGAECLTGGARGTREGDLADGFYMQPTVFKGHNKMRIF QEEIFGPVLSVTTFKDDEEALSIANDTLYGLGAGVWTRDGTRAYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRE THKMMLDHYQQTKNMLVSYSSKKLGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 8e-148 | 64 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-153 | 63 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-153 | 63 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-153 | 63 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 4e-153 | 63 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 6e-69 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| aldA | YP_003069697.1 | aldehyde dehydrogenase, chloroacetaldehyde dehydrogenase | VFG0082 | Protein | 3e-148 | 64 |
