Gene Information

Name : guaA (METDI3699)
Accession : YP_003069189.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Unknown
Product : GMP synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3638652 - 3640217 bp
Length : 1566 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3894345; Product type e : enzyme

DNA sequence :
ATGACCATCGATACCTCCCACCACGACAAGATCCTGATCGTCGATTTCGGCTCCCAGGTGACGCAGCTCATCGCCCGCCG
CGTGCGCGAGGAGGGCGTCTATTGCGAGATCGTGCCGTTCACGAAGGCCGAGGCCGCCTTCGAGGCGCACCGGCCCAAGG
GCGTGATCCTCTCCGGAGGCCCGGAATCGGTGACGACGGATCTCTCGCCGCGCGCCCCGCAAAAAATCTTCGAATCCGGC
GTGCCGGTCTTCGGCATCTGCTACGGCCAGCAGACCATGGCGGCCCAGCTCGGCGGCGAGGTCGAGGGCGGCCACCATGC
CGAGTTCGGCCGTGCGGAGGTCGAGATCGTCTCGGATTCGCCGCTGTTTCGGGGGGTCTGGCACGCGGGTGAGAAATACC
CGGTCTGGATGAGCCACGGCGACCGGGTGACGAAGCTGCCGGACGGCTTTGCCACCATCGCGATGTCGCGCAACGCGCCC
TTCGCCGCGGTGGCGGACGAGGCCCGCCATTACTACGCCGTCCAGTTCCATCCGGAGGTGCACCACACCCCGCACGGCGC
GCTGCTGATCCGCAACTTCGTGCGCGACATCGCCGGCTGCTCCGGCGACTGGACCATGGGCACCTACCGCGAGGAGGCGA
TCGCCAAGATCCGCGAGCAGGTCGGCAAGGAAAAGGTGATCTGCGGCCTCTCCGGCGGCGTCGATTCCTCGGTCGCGGCG
GTGCTGATCCACGAGGCGATCGGCGATCAGCTCACCTGCGTCTTCGTCGATCACGGCCTGATGCGCCTCGGCGAGGGCGA
CGAGGTCGTCCGCCTGTTCCGCGACCACTACAACATCCCCCTTGTCCACGTTCAGGCGCAGGATCTGTTCATCGGCGCGC
TCGAGGGCGTCGATGACCCCGAGGTGAAGCGCAAGACGATCGGCCGGCTGTTCATCGACGTGTTCGAGGCCGAGGCCGGC
AAGATCGGTGGCGCCGCCTTCCTCGCCCAGGGCACGCTCTATCCGGACGTGATCGAGAGCGTCTCGTTCTCCGGCGGCCC
CTCCGTGACGATCAAGAGCCACCACAATGTCGGCGGCTTGCCCGAGCGGATGAACATGAAGCTCGTGGAGCCCCTGCGCG
AGCTGTTCAAGGACGAGGTTCGCCTGCTCGGCAAGGAGCTCGGCCTGCCCGAGAGCTTCGTCGGCCGCCACCCCTTCCCC
GGACCGGGCCTCGCCATTCGCTGCCCCGGGATGATCACGCGCGAGAAGCTGGAGGCCCTGCGCAAGGCCGACGCGATCTA
TCTCGACGAGATCCGGCAGGCCGGCCTCTACGACACGATCTGGCAGGCCTTCGCGGTGATCCTGCCGGTGAAGACGGTGG
GCGTGATGGGCGACGGGCGCACCTACGACCATGTCTGCGCCCTGCGCGCCGTCACCTCGGTCGATGGCATGACCGCCGAC
TTCTACCCCTTCGACATGGCCTTCCTCGGCCGCGTCGCGACGCGGATCATCAACGAGGTGAAGGGCATCAACCGGGTGAC
CTACGACATCACCTCGAAGCCGCCCGGCACGATCGAGTGGGAATGA

Protein sequence :
MTIDTSHHDKILIVDFGSQVTQLIARRVREEGVYCEIVPFTKAEAAFEAHRPKGVILSGGPESVTTDLSPRAPQKIFESG
VPVFGICYGQQTMAAQLGGEVEGGHHAEFGRAEVEIVSDSPLFRGVWHAGEKYPVWMSHGDRVTKLPDGFATIAMSRNAP
FAAVADEARHYYAVQFHPEVHHTPHGALLIRNFVRDIAGCSGDWTMGTYREEAIAKIREQVGKEKVICGLSGGVDSSVAA
VLIHEAIGDQLTCVFVDHGLMRLGEGDEVVRLFRDHYNIPLVHVQAQDLFIGALEGVDDPEVKRKTIGRLFIDVFEAEAG
KIGGAAFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRLLGKELGLPESFVGRHPFP
GPGLAIRCPGMITREKLEALRKADAIYLDEIRQAGLYDTIWQAFAVILPVKTVGVMGDGRTYDHVCALRAVTSVDGMTAD
FYPFDMAFLGRVATRIINEVKGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-129 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-129 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-115 51