Gene Information

Name : dfrA (METDI3418)
Accession : YP_003068918.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 3339849 - 3340349 bp
Length : 501 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence :
ATGGCTCGACCCCGCATCTCTCTGGTCGCAGCCATCGCCCGCAACGGCGTGATCGGCCGCGACAACAGCCTCGCGTGGCG
GCTTTCCAGTGACCTGAAGCGCTTCAAGGCGCTCACCATGGGCAAGCCGATCCTGATGGGTCGCAAGACTTGGGATTCGA
TCGGCCGCCCCCTGCCCGGGCGGCGCAGTCTGGTCATTACCCGCGACCGCAGCCTCACCCTCCCCGACGTGACCGTCGTG
CATGATTGGGACGAAGCGCTCGCCGCGGCTGGGGACGACGAACTGATGGTGGTGGGCGGCGCCGAGATCTACCGGCTCGC
CCTGCCCCATGCCGACCGGCTGCATCTCACCGAAGTCGATGCGGCGCCCGAGGGCGATGCGTACTTTCCGCCCTTCGACC
GGGCTCTCTTCCGTGAGACGTTGCGCGAGGCGCACGGCCCCGGCGAGCGCGACGAGTTCGCGTTTCAATTTGTGGACTTG
GAGCGGTTGGGCAGCCGTTGA

Protein sequence :
MARPRISLVAAIARNGVIGRDNSLAWRLSSDLKRFKALTMGKPILMGRKTWDSIGRPLPGRRSLVITRDRSLTLPDVTVV
HDWDEALAAAGDDELMVVGGAEIYRLALPHADRLHLTEVDAAPEGDAYFPPFDRALFRETLREAHGPGERDEFAFQFVDL
ERLGSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 4e-21 47