Gene Information

Name : thiC (METDI2276)
Accession : YP_003067825.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein thiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2168113 - 2170005 bp
Length : 1893 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8432721; Product type e : enzyme

DNA sequence :
ATGAACGCACCCGTCCGTCCCAAAGATCTTCCCAACAGCAATCCCGCCAGCGTGACCACCGGCCCCGTGCAGGGCTCGCG
CAAGGTCTATGCGGAGGCGCCCGGCCGCCCCGACATCCGCGTGCCCTACCGGGAGATCGCCCTCTCCGACCCGAAGGAGG
AGCCGGTGCGGGTCTACGACCCGTCGGGCCCCTACACCGAGACCGATGCGGCCATCGACCTCGAGAAGGGTCTGGCCCCG
GTCCGCGAGCCGTGGATCGTCGGGCGCGGCTACGCCGCCGTGAAGCCGCGCGAGGTGAAGCCGGAGGACAACGGATTTGC
GGCTGCCGACAAGCTCGTGGCGCCGTGCCCCGCCGAGCGGACGATCCGCCGGGCCGAGCCGGGGCAGCTGGTGACGCAGT
ACGAGTTCGCCCGCGCCGGGATCATCACCGAAGAGATGATCTACGTGGCGCATCGCGAGAATGCCTGCCGCGCGCAGATG
CTGGAGCGGGCGGAAGCCGCGCTCGCCGACGGCGACAGCTTCGGCGCGGCGGTGCCGCCCTTCATCACGCCCGAATTCGT
TCGCGACGAGGTCGCCCGCGGGCGCGCGATCATCCCGGCCAACATCAATCACCTCGAACTCGAGCCGATGGCGATCGGCC
GCAATTTTTTGGTGAAAATCAACGCCAATATCGGCAACTCGGCGGTGACGTCTTCCGCGGCTGAGGAAGTCGAAAAACTG
GTCTGGTCGATCCGCTGGGGTGCGGACACGGTCATGGACCTCTCGACGGGCCGCAACATCCACAACATCCGCTCGTGGAT
CGTGCGCAACTCGCCCGTCCCGATCGGCACCGTGCCGATCTATCAGGCGCTGGAAAAGGTCGGCGGCGACCCGCTGAAGC
TCGATTGGGAGGTGTTCAAGGACACGCTCATCGAGCAGGCCGAGCAGGGCATCGACTACTTCACGATCCATGCCGGCGTG
CGGCTGGCTCACGTGCCGCTGACCGCGCGGCGCACCACCGGCATCGTGTCGCGCGGTGGCTCGATCATGGCGCGCTGGTG
CCTTGCCGGGCACCGCGAATCGTTCCTCTACGAGCGGTTCGACGAGATCTGCGACATCATGCGGGCCTACGACGTCTCGT
TCTCGCTCGGCGACGGCCTGCGCCCGGGCTCGATTGCGGATGCCAACGACGCGGCCCAGTTCGCCGAGCTGGAGACCCTG
GGCGAACTCACCAAGATCGCCTGGGACAAGGGCTGCCAGACCATGATCGAGGGCCCCGGCCACGTGCCGATGCACAAGAT
CAAGGTCAACATGGAGAAGCAACTGCGCGAGTGCGGCGAGGCCCCGTTCTACACGCTTGGCCCGCTGACCACCGACATCG
CCCCGGGCTACGACCACATCACCTCGGGCATCGGCGCCGCGATGATCGGCTGGTTCGGCACGGCGATGCTCTGCTACGTC
ACGCCGAAGGAGCATCTCGGCCTGCCGAACCGCGACGACGTGAAGACCGGCGTCATCACCTACAAGATCGCCGCGCACGC
CGCCGACCTCGCCAAGGGCCACCCCGCCGCGCAGCTCCGCGACGATGCCCTCAGCCGCGCCCGGTTCGACTTCCGCTGGG
AGGATCAGTTCAACCTCTCGCTGGATCCCGACACGGCGCGCGCCTACCACGACGAGACCCTGCCAAAGGACGCGCACAAG
GTCGCCCATTTCTGCTCGATGTGCGGCCCGAAATTCTGCTCGATGAAGATCACGCAGGATCTGCGCGCCGACGTGCTCGC
GATGGAAGAGGCTGGCATCGTCATCGGCCAAGCCCAGCCAATGAGCGACGCCGAGCGCCAGGCCGGCATGGCGGCCAAGT
CGCAGGAGTTCCTGGAAGAGGGCGGCAAGCTCTACGTCGACGCGGCGGAGTAA

Protein sequence :
MNAPVRPKDLPNSNPASVTTGPVQGSRKVYAEAPGRPDIRVPYREIALSDPKEEPVRVYDPSGPYTETDAAIDLEKGLAP
VREPWIVGRGYAAVKPREVKPEDNGFAAADKLVAPCPAERTIRRAEPGQLVTQYEFARAGIITEEMIYVAHRENACRAQM
LERAEAALADGDSFGAAVPPFITPEFVRDEVARGRAIIPANINHLELEPMAIGRNFLVKINANIGNSAVTSSAAEEVEKL
VWSIRWGADTVMDLSTGRNIHNIRSWIVRNSPVPIGTVPIYQALEKVGGDPLKLDWEVFKDTLIEQAEQGIDYFTIHAGV
RLAHVPLTARRTTGIVSRGGSIMARWCLAGHRESFLYERFDEICDIMRAYDVSFSLGDGLRPGSIADANDAAQFAELETL
GELTKIAWDKGCQTMIEGPGHVPMHKIKVNMEKQLRECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYV
TPKEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWEDQFNLSLDPDTARAYHDETLPKDAHK
VAHFCSMCGPKFCSMKITQDLRADVLAMEEAGIVIGQAQPMSDAERQAGMAAKSQEFLEEGGKLYVDAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-178 61