Gene Information

Name : ureC (METDI1898)
Accession : YP_003067458.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 1777618 - 1779336 bp
Length : 1719 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme

DNA sequence :
ATGAGCAAAATCTCGCGGCGGCAATACTCGGATCTCTACGGGCCGACGACAGGCGACAAGATCAGGCTCGCCGATACGGA
CCTCTACATCGAGATCGAGAAGGACCTTCGGGTTTACGGCGAGGAGGCCGTCTATGGCGGCGGCAAGACGCTTCGGGACG
GCATGGGTTACGACAACGAGTTGACCAGTGCGGCGGGCGCACCGGATCTCGTCATCACCAATGTCACGATCCTCGACGCG
GTCCAGGGCGTCATCAAGGCCGATCTCGGCATCAAGAACGGCCTGATCGTCGGAATCGGGAAGGCCGGCAATCCCTCGAC
GATGTCGGGGGTGACACGGGGTCTCGCGCTCGGACCGGGCACGGACGCCATTTCCGGCGAGCACCTCATCCTGACCGCGG
GCGGCATCGACGCCCACGTCCACTTCATCTCGCCGCAGCAGGCCCAGGCCGCGCTCAGCAACGGTGTGACGACGCTGTTC
GGCGGCGGCATCGGTCCATCCGACGGCACCAACGGCACGACCATCACGCCGGGCACGTGGAACATCGAGATGATGCTCCG
CTCCTTCGACGCTTGGCCGATCAATGCGGGCGTGCACGGCAAGGGCAATTGCTCGGCGCTCCTCCCGATCGAGGAGCAGA
TCCGGGCCGGCGCGATGGGTTTGAAGGTTCACGAAGACTGGGGCAGCACTCCGGCGGCGATCCGCATGGCCCTGACCGCC
GCGGACGATCACGACGTCCAAGTCTGCATCCACACGGACACCCTGAACGAGGCGGGTTTCGTCGAGAGCACCATCGCCGC
GTTCGAGGGGCGCACGATCCACACCTACCACACGGAGGGCGCGGGCGGCGGCCACGCCCCGGACATCATCCGGGTGGCTA
GCATTTCCAACGTCATCCCCAGTTCGACCAATCCGACCATGCCCTACGGCATCAATTCGCAGGCGGAATTGTTCGACATG
GTGATGGTCTGTCACAACCTCAGCCCGAAGATCCCGACGGACGTCGCCTTCGCGGAAAGCCGCGTGCGCGCCGAGACCAT
CGCGGCGGAAAACGTCCTGCACGATCTCGGTGCGATCTCGATCCTGTCGAGCGACAGCCAGGCCATGGGCCGCGTCGGCG
AGAACTGGGCGCGCACCATTCAGACAGCCCATCTGATGAAGGCGCGGCTCGGTGCCTATCCGGGGGATGCGTCCGGCAAC
GACAATCAGCGCGTGCTGCGCTTCGTCGCCAAGGTGACGATCAATCCCGCCATCGTGGCGGGGGTGTCGCACGTGATCGG
GTCGGTCGAGGTCGGCAAGATGGCGGACCTCGTTCTCTGGGAACCGGCCTTCTTCGGCGCCAAGCCGAAGATGGTCATCA
AGGGCGGCATGATCTCCTGGGCGATCATGGGAGATCCCAACGCCTCGCTGCCGACACCGCAGCCGGTCGTCTATCGCCCG
ATGTTCGGCGCTCTCGGCCCGGCCGTGGCGAAGACGCGCGTGACCTTCACGTCTCATGCCGCCTACGAGGACGGGATCGT
GGATCGTTACGAGCTGACGTCCAAGGTCGTGCCCGTCTACGGCACGCGCACCATCACCAAGGCGTCGATGGTTCGAAACG
ACCGGCTTCCGGTCATCGAGGTCAACCCGGAAACCTTCGCAGTGATGGTCGACGGCAAGCACGCCACGATCGAGCCTGCA
ACGCATCTTCCGCTCGCGCAGCTCCACTTCTTCAGCTGA

Protein sequence :
MSKISRRQYSDLYGPTTGDKIRLADTDLYIEIEKDLRVYGEEAVYGGGKTLRDGMGYDNELTSAAGAPDLVITNVTILDA
VQGVIKADLGIKNGLIVGIGKAGNPSTMSGVTRGLALGPGTDAISGEHLILTAGGIDAHVHFISPQQAQAALSNGVTTLF
GGGIGPSDGTNGTTITPGTWNIEMMLRSFDAWPINAGVHGKGNCSALLPIEEQIRAGAMGLKVHEDWGSTPAAIRMALTA
ADDHDVQVCIHTDTLNEAGFVESTIAAFEGRTIHTYHTEGAGGGHAPDIIRVASISNVIPSSTNPTMPYGINSQAELFDM
VMVCHNLSPKIPTDVAFAESRVRAETIAAENVLHDLGAISILSSDSQAMGRVGENWARTIQTAHLMKARLGAYPGDASGN
DNQRVLRFVAKVTINPAIVAGVSHVIGSVEVGKMADLVLWEPAFFGAKPKMVIKGGMISWAIMGDPNASLPTPQPVVYRP
MFGALGPAVAKTRVTFTSHAAYEDGIVDRYELTSKVVPVYGTRTITKASMVRNDRLPVIEVNPETFAVMVDGKHATIEPA
THLPLAQLHFFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-149 58
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-149 58
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-140 56
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-140 56
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-140 56
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-140 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_003067458.1 urease subunit alpha VFG0270 Protein 2e-141 58