Gene Information

Name : ureC (METDI1776)
Accession : YP_003067341.1
Strain : Methylobacterium extorquens DM4
Genome accession: NC_012988
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1648281 - 1649993 bp
Length : 1713 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 8288539; Product type e : enzyme

DNA sequence :
ATGGTCACGATCCCAAGGCGCGATTACGCCGCCCTCTACGGCCCCACCACCGGCGACGCCGTGCGGCTCGCCGACACCTC
CCTCGTCGCGGTGGTCGAGCACGACCACGCGGTCTACGGCGACGAGTGCCTGCATGGCGGCGGCAAGACTCTTCGGGATG
GCATCGGGCTCGCGCCCGGCGTCACGGCGGCGCAAGGAGCCCTCGACTTCCTCCTGTGCAACGTGCTCGTGATCGATCCC
GTCCTCGGCATCGTGAAGGGCGATCTCGGCATCAAGGACGGGCGCATCGTCGGCCTCGGCAAGGCCGGCAACCCGGCGAT
CATGGACGGCGTCGATCCGCGCCTGATCGTGTCGGCCGGCACCACCGTGCGCGACTGCGAGGGGCTGATCGCGACGCCGG
GCGCCATCGACGTTCACGTGCACTTCGATTCCGCCGGCCTGCCCGACCACGCCATCGCCTCAGGGATCACGACGCTGCTC
GGCGGCTCGCTCGGGCCGATCACCGTCGGCATCGATTCCGGCGGGCCGTTCAACACGGGAAAAATGCTCCAGGCGGCCGA
AGCCTGGCCCGTCAATTTCGGTTTTTTGGGAAGGGGCAACACCCACAAGCCGGCGGCCTTGAAGGAACAGCTTGAGACCG
GCGTGCTCGGCCTCAAAATCCACGAGGATTGGGGGGCGATGCCGGCGGCGATCGATGCCTGCCTCGGCTTTGCCGACGAA
TACGACTTCCAGGTCCAGCTCCACACCGACACGCTCAACGAGTCGGGCTTCGTGGAGGACACGCTGGCGGCGATCGGCGG
CCGCACGATCCACATGTACCACACCGAGGGCGCGGGCGGCGGGCACGCGCCCGACATCATCCGCGTGGCAGGGCTGCCCC
ACTGCCTGCCCTCCTCGACGAACCCGACCAATCCCTACACGGTCAACACGTTCGACGAGCACCTCGACATGACGATGGTG
TGCCACCACCTCAACCCGGCTCTGCCGGAGGACGTGGCCTTCGCCGAGAGCCGCATCCGCGCGCAGACCATCGCGGCCGA
GGACGTGCTGCACGATATCGGCGCGATCTCGATGCTCGGCTCCGACAGCCAGGGCATGGGCCGCATCCACGAGGTGATCT
GCCGGACATGGCAGCTCGCCTCCAAGATGAAGGACCAGCGCGGGAGCCTGCCGGAGGAGCGGCCGGGCTTCGGCGACAAT
GCCCGGATCAAGCGCTACATCGCCAAGTACACGATCAACGCCGCGCGCACCTTCGGCATCCAGGAGCATATCGGCTCGCT
AGAGCCCGGCAAGATGGCCGACATCGTGATCTGGCGCCCGGCCTTCTTCGGCATCAAGCCGGAACTCGTGATCAAGGGCG
GCTTCATCGCCTGGGGCGCCATGGGCGATTCCGCGGCCTCCCTGATGACCTGCGAGCCGATGCTGATGCGCCCGCAATGG
GGCGCCTTCGGGCTGGCCAAGCAGGGGCTGTCGGCCTGCTTCGTCCACCCGCTCGCCATCGAAGGGGGACTGCGCGAGAG
CCTTGGCCTTCGCAAAGGACTGCTGCCGGCCCGCGGCACCCGCACGCTGACCAAAGCCGACATGCTCTGGAACGACGCCT
GCCCGGAGATCCGGGTCGACCCGCAGACCTTCGAGGTCTTCGTGGACGGGGAACTCGCCACTTGCGAGCCCGCAACCGTC
CTCCCGCTCGCCCAACGCTACATGCTGCGATGA

Protein sequence :
MVTIPRRDYAALYGPTTGDAVRLADTSLVAVVEHDHAVYGDECLHGGGKTLRDGIGLAPGVTAAQGALDFLLCNVLVIDP
VLGIVKGDLGIKDGRIVGLGKAGNPAIMDGVDPRLIVSAGTTVRDCEGLIATPGAIDVHVHFDSAGLPDHAIASGITTLL
GGSLGPITVGIDSGGPFNTGKMLQAAEAWPVNFGFLGRGNTHKPAALKEQLETGVLGLKIHEDWGAMPAAIDACLGFADE
YDFQVQLHTDTLNESGFVEDTLAAIGGRTIHMYHTEGAGGGHAPDIIRVAGLPHCLPSSTNPTNPYTVNTFDEHLDMTMV
CHHLNPALPEDVAFAESRIRAQTIAAEDVLHDIGAISMLGSDSQGMGRIHEVICRTWQLASKMKDQRGSLPEERPGFGDN
ARIKRYIAKYTINAARTFGIQEHIGSLEPGKMADIVIWRPAFFGIKPELVIKGGFIAWGAMGDSAASLMTCEPMLMRPQW
GAFGLAKQGLSACFVHPLAIEGGLRESLGLRKGLLPARGTRTLTKADMLWNDACPEIRVDPQTFEVFVDGELATCEPATV
LPLAQRYMLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 7e-127 56
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 7e-127 56
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-138 54
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-138 54
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-138 54
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-138 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_003067341.1 urease subunit alpha VFG0270 Protein 5e-128 51