Name : zntA (METDI1261) Accession : YP_003066877.1 Strain : Methylobacterium extorquens DM4 Genome accession: NC_012988 Putative virulence/resistance : Resistance Product : zinc, cadmium, cobalt and lead efflux system Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : 3.6.3.3 Position : 1147726 - 1149921 bp Length : 2196 bp Strand : - Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 10660539, 12746428, 21305696, 9364914, 9405611, 98070750, 99428388; Product type t : transporter DNA sequence : ATGAACCAAGCCGCCCCTACGGACCCGACATCATCTCCCACCACGGGCAATCAGGCCCTGCGCTACAGAGTCAAGGGCAT GGACTGCCCAACCTGCGCCGGGAAGATCGAGAACGCCGTCTCCCGGCTGCCGGGTGTCGCGGACGTTCGCGTAAACTACG GCAGCCAGGTTCTCGACCTGGCGCTCGACGAGGGCGTCACCCCGAGGACCGAGTTGGAGGGGCGCGTCGAACGCCTGGGC TACGGCGTCGCGCCGCTGCCCACGGCCGCGGACCTGGCCAAGGCCCGGGCCGAGGGTGTCGCCCCGCCGGCCGGGACCAT GGAGGATGCCGAACCGCCGCTCTGGCGGAGCCGCAAGGCGCTGCTGGGCATTCTCATCGGCACCCTGTTCGCCGCCGGGT TCATCGTCGAGCGGATCGCGCCCGGCTTGGCGGGCGAGTACGCCTACTGGCCGGGGGCGCTCGTCGGGCTCGCCTATTAC GGGCGCCGCGCGGTCGTGGCGGCCACGGCCGGCACGCCTTTCTCCATCGAGATGCTGATGTCGGTGGCGACGGCGGGGGC GCTGGCCATCCATGCGGCCGAGGAGGCCGCCATCGTCGTCCTGCTCTTCACGGTCGGCGAGATGTTGGAGGTCGTGGCGG CGGGGCGCGCACGCGCCGGCATCAAGGCGCTTGCGGCCCTGGTGCCTAAGACTGCCCGCCTCGTCGACGAAGCCGACGGC ACGATCCGGGAGGTGCCCGCGGCGTCGCTCGCCATCGGGCAGGTCGTCGTGGTGAGGCCGGGCGACCGCGTGCCCGCCGA CGGCGTGATCACGGATGGCTCGTCGAGCCTCGACGAGTCCCCCATCACCGGCGAGTCGGTCCCGAAGGCCAAGGAGGTTG GTGACACGGTCTACGCCGGCAGCGTCAACGCCGACGGCGCACTCCAGGTCCGCGTCACCAAGACAGCGGCGGACAACACG GTCGCCCGCATCCTCCACTTGGTCGAGGAGGCGCAGGCATCGAAGTCGCCCACGGCCCGCTTCATCGACCGGTTCAGCGC GGTCTACACGCCCATCGCCTTCGCATTCGCGGCCGCCGTCGCGGTCCTGCCGCCGCTCCTCGGTGCCGACTGGGGCACTT GGGTCTACCGGGGGCTCGCGCTCCTCCTCATCGCCTGCCCCTGCGCCCTCGTGCTCTCGACGCCGGCGGCCATCGCATCG GGGTTGGCCGCCGGGGCGCGGCGCGGGCTGCTCGTGAAGGGCGGGGCGGCGCTGGAGGTCATCGGGCGGGTGCGCACGGT GGCGTTCGACAAGACGGGAACCCTGACGGCTGGACGGCCGCGGGTCACCGACATCCTGGTCTTCGCGCCGGATGCGTCGG AGCGCTCGCTTCTCGGATTGGCCGCCGCAGTCGAGAACGGGTCCAGCCATCCCATCGCCCGGGCCATCCTGGACCGGGCG AACGAGGACGGGGTGCCGCTCCGGCCGACGCGCGATGCCCGCGCCACCCCCGGCAAGGCCGTGCAGGCCACGGTCATGGG CCAGACGGTGCTTGTGGCCTCGCCGCGCCACGCCGCCGATAGCCTCCGGCTTGGCCCGGAGGCGGACCGTGCCGTCGCCG GCCTGGAGACCAGTGGCAAGACGGTGGTCATCATCATCCGCGGCACCGAGGCACTGGGCGCCATCGCGGTCCGGGACGAG CCCCGTGCCGACGCGGCCGCCGGCATCGCGGCCCTGCGGAAGCTGGGCGTGCGCAGCGTGATGCTGACCGGCGACAATCG CCGCGCGGCCGAGGCGGTCGCGTCCGAACTCGGCCTCGACGTGAAGGCCGAGCTCCTGCCGCAAGACAAGCTCGCCGAGA TCGCGGCCCTGAAGGAGGAGGGCCCGGTCGCGATGGTCGGCGACGGCATCAATGACGCGCCTGCCCTGGCCTCCGCCAGC GTCGGCATCGCGATGGGCGGCGGCACGGACGCGGCCCTGGAAACGGCGGACGCCGCGGTGCTGAACGACCGCGTGGGAGA CGTGGCCGCCCTCGTCGCCTTGTCCCGGGCGACGCTGGGAAACATCCGCCAGAACGTCGCCATCGCGCTCGGCCTGAAGG CGGTGTTCCTGGTGACGACCATCGCCGGCATCACCGGCCTCTGGCCCGCCATCCTGGCCGATACCGGCGCGACCGTCCTG GTGACGGCCAACGCGCTCCGTCTCCTGAGGGCATGA Protein sequence : MNQAAPTDPTSSPTTGNQALRYRVKGMDCPTCAGKIENAVSRLPGVADVRVNYGSQVLDLALDEGVTPRTELEGRVERLG YGVAPLPTAADLAKARAEGVAPPAGTMEDAEPPLWRSRKALLGILIGTLFAAGFIVERIAPGLAGEYAYWPGALVGLAYY GRRAVVAATAGTPFSIEMLMSVATAGALAIHAAEEAAIVVLLFTVGEMLEVVAAGRARAGIKALAALVPKTARLVDEADG TIREVPAASLAIGQVVVVRPGDRVPADGVITDGSSSLDESPITGESVPKAKEVGDTVYAGSVNADGALQVRVTKTAADNT VARILHLVEEAQASKSPTARFIDRFSAVYTPIAFAFAAAVAVLPPLLGADWGTWVYRGLALLLIACPCALVLSTPAAIAS GLAAGARRGLLVKGGAALEVIGRVRTVAFDKTGTLTAGRPRVTDILVFAPDASERSLLGLAAAVENGSSHPIARAILDRA NEDGVPLRPTRDARATPGKAVQATVMGQTVLVASPRHAADSLRLGPEADRAVAGLETSGKTVVIIIRGTEALGAIAVRDE PRADAAAGIAALRKLGVRSVMLTGDNRRAAEAVASELGLDVKAELLPQDKLAEIAALKEEGPVAMVGDGINDAPALASAS VGIAMGGGTDAALETADAAVLNDRVGDVAALVALSRATLGNIRQNVAIALGLKAVFLVTTIAGITGLWPAILADTGATVL VTANALRLLRA |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 1e-96 | 41 |
unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 7e-97 | 41 |
Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
zntA | YP_003066877.1 | zinc, cadmium, cobalt and lead efflux system | BAC0461 | Protein | 9e-108 | 48 |
zntA | YP_003066877.1 | zinc, cadmium, cobalt and lead efflux system | BAC0092 | Protein | 7e-71 | 42 |
zntA | YP_003066877.1 | zinc, cadmium, cobalt and lead efflux system | BAC0124 | Protein | 1e-71 | 42 |