Gene Information

Name : guaA (JDM1_0761)
Accession : YP_003062345.1
Strain : Lactobacillus plantarum JDM1
Genome accession: NC_012984
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 814143 - 815699 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGGCAAAAACGGATACCGCGTCTTTCGATTCCATTTTGGTATTGGATTTCGGTAGTCAGTATAATCAATTGATTACCCG
GCGCATTCGTGATTTCGGCGTTTATTCGGAACTACTTCCGAACACGATCACCGCTGAAGAAATCAAGGCCCGTCACCCGA
AAGGTATTATCTTTTCTGGTGGCCCCAACAGTGTTTACGATGATGGCGCCTTTCGGGTTGACCCGGAGATTTTCAAGTTG
GGCTTACCAATCTTGGGGATTTGTTACGGCATGCAACTGATGACCTACACGCTTGCGGGCGGGAAGGTCGAATCAGCTGA
TAACCGTGAATACGGTAAGGCGAACATTGACGTGACGAGTGACTCGGCGACCCTATTTAAGGACACGCCAGCTGAACAGT
CAGTGTGGATGAGTCATGGTGACTTGGTTACTCAAGCACCTGATGGTTTTGACGTGGTGGCCACTTCTAAGAACTGCCCG
ATTGCGGCAATTCAAGATGTTGACCGGAAGTTATATGGGATTCAATTCCATGCTGAAGTTCGGAATACGGACTACGGTAA
TGATATTCTACGGCACTTTGCATTTGACGTTTGCCAAGCTGAAGCTAACTGGTCAATGGATGATTTCATTGATATGCAGA
TTGAAAAGATCCGCGCTGAAGTTGGCGACAAAAAGGTCTTACTGGGACTTTCCGGTGGGGTTGATTCCAGTGTCGTCGGT
GTGTTATTGCACAAGGCCATTGGCACGCAATTAACAAGTATTTTCGTTGACCATGGTTTGTTACGGAAGGGCGAAGCTGA
TCAAGTTATGGCGAGCCTAGAAGGTAAGTTCGGCTTGAACATCATCAAAGTTGATGCTAAGGACCGCTTCTTAAGCAAGT
TGGCTGGTGTCAGTGATCCTGAACGGAAACGTAAGATTATTGGTAACGAATTTATCCAAGTGTTTGATGAAGAAGCCACG
AAGTTAAACGGGATGGAATTCCTCGCACAGGGGACCCTCTACACCGATGTGATTGAAAGTGGGACTTCAACGGCCCAAAC
AATCAAGTCACATCATAATGTTGGTGGTTTGCCAGAAGACATGCAGTTCAAGTTGATTGAACCGCTACGGACGTTATTTA
AGGACGAAGCACGGGAACTCGGTGAAAAGCTAGGGATGCCGTCTGACCTTGTTTGGCGTCAACCATTCCCCGGCCCTGGT
CTCGGAATTCGGGTTATTGGTGAGATTACGGAAGATAAGTTAGAAATCGTGCGCGATAGTGACTTTATCTTACGTGATGA
AATCAAAAAAGCCGGCTTGGACCGTGAAATCTGGCAATACTTCACCGTATTACCAGGCATCAAGTCAGTCGGTGTCATGG
GTGACGGCCGGACCTACGATTACACCGTTGGTATTCGGGCCGTGACATCAATCGACGGTATGACCGCCGACTTTGCACGT
ATTCCATGGGATGTCTTACAAAAGATCTCAGTGCGGATCGTCAATGAAGTCGATCACGTTAACCGCATCGTGTACGATGT
TACGAGTAAGCCACCTTCGACAATTGAATGGGAATAG

Protein sequence :
MAKTDTASFDSILVLDFGSQYNQLITRRIRDFGVYSELLPNTITAEEIKARHPKGIIFSGGPNSVYDDGAFRVDPEIFKL
GLPILGICYGMQLMTYTLAGGKVESADNREYGKANIDVTSDSATLFKDTPAEQSVWMSHGDLVTQAPDGFDVVATSKNCP
IAAIQDVDRKLYGIQFHAEVRNTDYGNDILRHFAFDVCQAEANWSMDDFIDMQIEKIRAEVGDKKVLLGLSGGVDSSVVG
VLLHKAIGTQLTSIFVDHGLLRKGEADQVMASLEGKFGLNIIKVDAKDRFLSKLAGVSDPERKRKIIGNEFIQVFDEEAT
KLNGMEFLAQGTLYTDVIESGTSTAQTIKSHHNVGGLPEDMQFKLIEPLRTLFKDEARELGEKLGMPSDLVWRQPFPGPG
LGIRVIGEITEDKLEIVRDSDFILRDEIKKAGLDREIWQYFTVLPGIKSVGVMGDGRTYDYTVGIRAVTSIDGMTADFAR
IPWDVLQKISVRIVNEVDHVNRIVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-173 72
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-173 72
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-173 72
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-128 50