Gene Information

Name : lysS (JDM1_0448)
Accession : YP_003062034.1
Strain : Lactobacillus plantarum JDM1
Genome accession: NC_012984
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 480979 - 482478 bp
Length : 1500 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGGCACGACAAGAACAGACGATGAACGACCAACTGAAGGTTCGTCGCGAAAAAATGGATGAACTGCGTGAAGAGGGGAT
TGATCCCTTTGGTCACCGGTTCGAACGGACTGATTTAGCCCAGGACTTGCAAGACAAGTATGGGGATATGGATAAGGACG
AGCTAGACGCTAAACAAGTGGTGGCAACCATTGCTGGACGGATGCTAGCTAAGCGTGGTAAGGGTAAAGTCGGTTTTGCT
GATATCTGGGATCGCTCAGGTAAGATGCAGTTATACATTCGTAAAGATGTAGTCGGCGAAGATACTTACCATATCTTCAA
GCGTTCTGATATTGGTGATTTCCTTGGAATTACCGGCCAAGTTTTTAAGACGGACTTTGGCGAATTAACGATTAAAGTAA
CTGGTTTAACGTTCTTATCAAAGGCGTTACGACCATTGCCAGATAAGTTCCATGGGTTACAGAATGTGGAACAGATCTAT
CGCCAACGGTATTTGGACTTGATCTCTAACCGCGATAGCTTTGATCGTTTCTTGAAGCGGACGAAGATCATTTCAGCGAT
TCGGCATCATTTAGACGATCAAGGCTTCACAGAAGTTGAGACGCCAATGTTGCATAATCAAGCTGGTGGTGCGGCAGCAC
GGCCATTTGTGACTCACCACAATGCGTTGAACATTGATCTCTACTTACGAATTGCGTTGGAATTACATTTGAAGCGCCTG
ATCGTTGGTGGCATGGAAAAGGTTTATGAGATTGGTCGGGTTTTCCGTAATGAAGGGATGGACCGTGAACATAATCCTGA
ATTTACCATGATGGAAACTTATGTCGCCTATTTCGACTTCCATGATGTAATGGCTGAGACGGAAGGTATTTTTAAAGCCG
CAGCGCAAGCCGTAACTGACGATGGCATTGTCACTTATCATGATCAAAAAGTTGATTTCAATCAACCATTTAAGCAAATT
CACATGGTCGATGCGATTAAAGAAAAGACTGGGATTGATTTCTGGCAACCAATGTCAATTGAAGATGCACAAAAATTGGC
GGATGAACATCACGTGAAGTATGAACCATACTGGAAAGTTGGTCATATCATTAATGCGTTCTTTGAAGAATTTGTTGAAG
ACACGTTGAATGAACCAACCTTTGTTTATGGTCATCCAGTTGAAATTTCGCCATTAGCTAAGAAGAATGAAGAAGATCCA
CGGTTTACTGATCGTTTTGAACTCTTCATCTTAGGTAATGAATACGCCAATGCGTTCAGTGAATTGAATGATCCAATTGA
CCAACGGCAACGTTTCGAAGCTCAGGCTGCGGAACGGACTGCTGGTAACGACGAAGCTGAACATATTGATGAAGACTTTG
TCGAGGCGTTGGAATACGGGATGCCGCCTACTGGTGGGTTAGGTATCGGGATTGATCGGTTGGTTATGTTAATGACGGAT
GCGGACTCGATTCGTGATGTCTTACTTTTCCCAACGATGCGTCCAGAAGAAGATAAATAA

Protein sequence :
MARQEQTMNDQLKVRREKMDELREEGIDPFGHRFERTDLAQDLQDKYGDMDKDELDAKQVVATIAGRMLAKRGKGKVGFA
DIWDRSGKMQLYIRKDVVGEDTYHIFKRSDIGDFLGITGQVFKTDFGELTIKVTGLTFLSKALRPLPDKFHGLQNVEQIY
RQRYLDLISNRDSFDRFLKRTKIISAIRHHLDDQGFTEVETPMLHNQAGGAAARPFVTHHNALNIDLYLRIALELHLKRL
IVGGMEKVYEIGRVFRNEGMDREHNPEFTMMETYVAYFDFHDVMAETEGIFKAAAQAVTDDGIVTYHDQKVDFNQPFKQI
HMVDAIKEKTGIDFWQPMSIEDAQKLADEHHVKYEPYWKVGHIINAFFEEFVEDTLNEPTFVYGHPVEISPLAKKNEEDP
RFTDRFELFILGNEYANAFSELNDPIDQRQRFEAQAAERTAGNDEAEHIDEDFVEALEYGMPPTGGLGIGIDRLVMLMTD
ADSIRDVLLFPTMRPEEDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-116 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_003062034.1 lysyl-tRNA synthetase VFG1668 Protein 2e-116 47