Gene Information

Name : Hbal_0631 (Hbal_0631)
Accession : YP_003059030.1
Strain : Hirschia baltica ATCC 59814
Genome accession: NC_012982
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 666094 - 669198 bp
Length : 3105 bp
Strand : +
Note : PFAM: acriflavin resistance protein; KEGG: pha:PSHAb0486 AcrB/AcrD/AcrF family metabolite exporter

DNA sequence :
ATGAACAGCGCAGTCCTATCGATTAAAAATCCACTTATATGCTCCATTTTCATGCTCATTGCTTTAATCGGTGGATGGTT
GGCATTTGAAAATATGGCGCGTTTTGAAGATCCTGAATTTACCATCAGGGTTGCTAAAGTGATCACGCAATATCCTGGGG
CTAGTCCTCAGGAAGTGTTGGATGAAGTCACTGAGCCGCTTGAATCTGCTTTGCAGCAATTGGCAGAAGTGGAGACTGTT
GAATCGCGCTCGTCTGCTGGATTGTCAGATATTTCTGTTGAAATTCGTTTTAAGGATTCAACCAGCAAAGAAGAGTTGAA
ACTAATTTGGACCAAGGTTCGGAACAAGATTTCGGATGCTCAAAATAGCCTGCCACCGGGCGCGCAACCTACGCAAGTTA
ATGATGATTTTGGTGATGTTTATGGTGTCTATTACCTTCTGACGGGAGAAGGGTATACGCCTGCAGAATTGGTCTCTTAT
GCCAAGACATTGCGTAAAGAATTGCTACGGGTAGACGGCGTAGCGAAAGTTGCCGTCACAGGCGAGCAAGAAGAAGTTAT
ATATGTTGAGGTTTCGCGTGCACGAGCGGCGGCCTTGGGTGTTTCTTTGAATGCTGTTTACGCAACGCTTTCGCAGCAGA
ATACGGTGTCTTCTTCGGGAGATATAGTCTTGGGGTCGGAACGGGTGGTTCTGCGCCTGAGTGGAGAAATCAATTCTGTT
GAAGCCATTGAGAATGTCATCGTCAATAATAGCGGCAATGGCTCAATTACCAATTTAGGGGCAGTGGCGAATGTTGTGCG
GGGATATAAAGAACCGACCGGTTTATATATTCGGCATGACGGGCAGCCCGCTTTAGCGATTGGTATTTCAAATGTTTCTG
GGGCGAATGTTGTTAAGCTCGGGCAAGCCATTGATGCGCGCCTTGCGGAAATAGAAAATCTGCGCCCCGTTGGGATGGAG
CTTCATGAGTTTTATCACCAAGGCAAAGTGGTCGATGAGGCGATTGTCAATTTTGCATGGAATGTGGTGGCAGCGCTGGT
CATTGTGTTCATGACGCTTCTAATTTTTATGGGATATCGTTCGGGCCTTGTCATGGGAATGACGGTGTTGATCACTATGG
CGGCAACACTGCTGATTATGTGGATTGCGGGCATTCCAATGCACCGCATTTCACTGGGCGCTTTGGTGATTTCGCTGGGT
ATGCTGGTCGATAATGGTGTGGTGATCACAGATGGAATACTGGTCGGCATCCATGAAGGGCGCAAAAAACTAGATATCGC
CAAAGACGTTGCACAAAAGAATATGAAACCGCTTTTAGGCGGGACATTGGTAGGAATTATCGCCTTTGCGCCAATTGGAT
TTTCTCCCGGTGAAGTTGGCGAATATACGGGCGATCTTTTCTGGGTGGTTATGATTGCGTTGGGATTGAGTTGGGTTTTT
GCCTTCACCTTCACCCCCTTGCTTTGTTACTGGATGTTCCCTGAAGGGCAGCCTAAAGCAGCGCAAGATTCTCAGAATGA
AGAAGAGCATGGTTTTTATAAAATTTATAAGAAGCTGATCAATGCGGTTCTGCAGGCAAAACGGCTAGTTATAATAGTTA
CGATTGGTGTTTTTTGTCTATCGGTTTGGGGCTTTCAGTTCGTTAAAGATGGCTTTTTTCCTTCGTCAACATCGCCGCAG
ATCGTTGTGGATTATTATTTACCCGAAGGCACAGATATTGAGCGAACCAACCAAGATATGAAGCGGATGGAAGATTTTGT
GCGCGGCTTGGAAGGCGTGGAGCAAGTTCAGACAATCGTTGGCGGAGGCACGCTGCGCTATATGTTGGTCTATCAGCCAG
CTGAAGCAAATGGGTCTGTGGGGCAGCTGTTAATTCAAACTTCAAAATACGAATTAAATGACGGATTGATCGCGCAAATT
CAAAATTTTGCAGTTCAGAATTTTCCCGATGGTCAGACAAAAGCATGGAAATTCCTGCTTGGTCCGGGAGGCGGCTCTAA
AATTGAAGCTCAGTTTACGGGTCCCGAAGCGAGTGTTTTGAGGCGTCTTGCCAATGAGGCCAAAGAAATTATGGCAAATG
ATCCTGACGCAATCATGGTGAAAGATGATTGGCGACGTCAATTACCGATTATTGAGCCAATCTATTCGCAAACAAAGGGT
GAGCGCGCAGGTATTACCCGTTTGGATATCACACAGGCATTAGAGGAGAATTTCTCTGGTCGTGAACGCGGCATTCTTCG
TGAAGGCGATGATTTGATAAAGATTATTTCGCGCGCGCCAGAAGCTGAACGCATTGGGCCTTGGAGCATCGCATCCCTGC
AAGTGTTGGGGGCGAACTCTCAGCAATCCGTGCCATTGGCACAGGTGCTCGAAAATATGAGGCTCACATGGAGAGACGCA
AATTTGCTGAGGATTGATCGCGCACTTACAATTACAGCACAGACCGATCCAGGTCTTGGTGTATTGACTGCGGATTTGTT
TGAAAGATTGCGGCCGCAGATTGAAGCAATCGAATTGCCTGAAGGGTATCATCTAGAGTGGAAAGGTGAATATGGGGATT
CTTCGGATGCTCAAGGAAAGCTAGCCAGCACATTGCCGCTAGGATTGCTGGCAATGGTGTTGGTCGTGGTCTTTTTGTTC
AATTCAGTGCGCCAACCTCTGATTATCTGGTTTGCTGTACCTTTGGCGATAGTGGGCGTTGTTGTCGGTCTTGTTATCAC
CCAGACTCCGCTTGAGTTTATGGGTATTCTTGGCTTGCTCTCATTATCGGGATTATTGATACAGAACTCATTGGTTCTTG
TTGATAGCATTGACAACAATATTGCGGACGGAATGCCTCGATATGAGGCTTTGTTAAATTCGTCGGCAAGTCGTTTGCGG
CCTGTGACGATGGGGGCATTTACGACCGTTTTGGGTGTGCTACCGCTTTATTTTGATGCTTTTTTTAGGTCCATGACTGT
TGTTCTGGTATTTGGTTTAACTTTCGCAACGTTGATTACATTGTTGGTAACGCCATCGTTATATGCGTTGATGTTTGGAA
TTCACAAAAATGAAGTTAGTAAGCCTATAGAAACTTCATTGCCTGAACAGGATGCGACAGCATGA

Protein sequence :
MNSAVLSIKNPLICSIFMLIALIGGWLAFENMARFEDPEFTIRVAKVITQYPGASPQEVLDEVTEPLESALQQLAEVETV
ESRSSAGLSDISVEIRFKDSTSKEELKLIWTKVRNKISDAQNSLPPGAQPTQVNDDFGDVYGVYYLLTGEGYTPAELVSY
AKTLRKELLRVDGVAKVAVTGEQEEVIYVEVSRARAAALGVSLNAVYATLSQQNTVSSSGDIVLGSERVVLRLSGEINSV
EAIENVIVNNSGNGSITNLGAVANVVRGYKEPTGLYIRHDGQPALAIGISNVSGANVVKLGQAIDARLAEIENLRPVGME
LHEFYHQGKVVDEAIVNFAWNVVAALVIVFMTLLIFMGYRSGLVMGMTVLITMAATLLIMWIAGIPMHRISLGALVISLG
MLVDNGVVITDGILVGIHEGRKKLDIAKDVAQKNMKPLLGGTLVGIIAFAPIGFSPGEVGEYTGDLFWVVMIALGLSWVF
AFTFTPLLCYWMFPEGQPKAAQDSQNEEEHGFYKIYKKLINAVLQAKRLVIIVTIGVFCLSVWGFQFVKDGFFPSSTSPQ
IVVDYYLPEGTDIERTNQDMKRMEDFVRGLEGVEQVQTIVGGGTLRYMLVYQPAEANGSVGQLLIQTSKYELNDGLIAQI
QNFAVQNFPDGQTKAWKFLLGPGGGSKIEAQFTGPEASVLRRLANEAKEIMANDPDAIMVKDDWRRQLPIIEPIYSQTKG
ERAGITRLDITQALEENFSGRERGILREGDDLIKIISRAPEAERIGPWSIASLQVLGANSQQSVPLAQVLENMRLTWRDA
NLLRIDRALTITAQTDPGLGVLTADLFERLRPQIEAIELPEGYHLEWKGEYGDSSDAQGKLASTLPLGLLAMVLVVVFLF
NSVRQPLIIWFAVPLAIVGVVVGLVITQTPLEFMGILGLLSLSGLLIQNSLVLVDSIDNNIADGMPRYEALLNSSASRLR
PVTMGAFTTVLGVLPLYFDAFFRSMTVVLVFGLTFATLITLLVTPSLYALMFGIHKNEVSKPIETSLPEQDATA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hbal_0631 YP_003059030.1 acriflavin resistance protein BAC0425 Protein 0.0 46
Hbal_0631 YP_003059030.1 acriflavin resistance protein BAC0519 Protein 3e-177 43
Hbal_0631 YP_003059030.1 acriflavin resistance protein BAC0428 Protein 5e-172 43