Gene Information

Name : Hbal_2560 (Hbal_2560)
Accession : YP_003060932.1
Strain : Hirschia baltica ATCC 59814
Genome accession: NC_012982
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 2755785 - 2757266 bp
Length : 1482 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: bur:Bcep18194_C6756 aldehyde dehydrogenase (acceptor)

DNA sequence :
ATGCTGAGCTATGAAAAACTATTTATTGATGGCGCTTGGGTTGCCCCGCTGGATGGATCAATTGAAGAGACAATAAACCC
TGCAACTGGCAAGCCTTGGGCAAAAGTTGCGTTTGGTGGGGCTCGAGACATTGATAAAGCAGTTGAGGCAGCAAAGCGGG
CATTAAGTGGACCGTGGGGAAAAATGACAGCAATAGAACGCGGTACATTGCTACGGCGTTTGGCAGATCTCTACCAAGCA
AATGCAAATGCACTAGCTGAATTGGAGACGAAAGATTCAGGCCGCGCGCTTCGAGAATCGAGGATGGATGTTGGCAGTCA
TCATCAATGGTATCGTTGGTTTGCATCTGTCGCTGAAACGAGACGTGGGAATACTATTCCGATAGATGACACTGTTCACG
CATATACATCGGAGGTTCCGGTTGGAGTCGTTGGGGCGATAACGCCGTGGAATGTACCTCTTATGATAACGGCTTGGAAG
TTGGCACCGGCTTTGGCCGCTGGCTGTACTATTGTGCTAAAACCGGCTGAACAAACGCCTGTTACAAGTTTAGAATTTGC
ACGGCTGGTAGAGGAGGCTGGTTTTCCTCCAGGTGTTGTGAATGTGGTTCCCGGAATTGGGAGCATAGCGGGCGCTGCTC
TTTCTTCCCATCGCGATGTAGATAAGGTTTCATTTACCGGCGAAGGGCAGACCGCGAAAACTATTCTGCAAAACAGCACT
GGCAATATGAAACGCTTTTCATTTGAGTTAGGAGGGAAAGCCCCTCACATCATTTTTGAAGATGCAGATCTCGAACAAGC
TATAAATGCAGCCACAAATTCATCATGGGCGTTGTGCGGCCAAAGCTGTGCATTAGGAGCCAGAGTTTTAGTTCAACGGT
CAGTTTACGAAAGAGTTGTTGAGGGGTTTGCGGAGCGAGCCAAACAGGTGAAAGTGGGGAATCCAAGTGATCCATCTATT
CACATGGGGCCGCAAGCTCATGGTGAGCAACTCTCTAAAACACTTTCATATATTCAAAGTGGGGTGGACGAAGGGGCCCG
ACTTGTCTCCGGTGGGAAATGTCTGACAGAGGGTGATCTTGCAGGCGGATTTTTTATAGAACCAACTGTTTTTGCTGATG
TTTCTAATAATATGAAGATTGCCAGAGAAGAGATTTTTGGTCCCGTAGCCTGCCTTATTCCTTTTGAAACAGAAGATGAA
GCCATCGCAATCGCAAATGACAGCGAATTTGGTTTGGCTTCAGGATTGTGGACGCGGGATATGGGGCGTGCTCATCGCGT
ATCATCGCAAATTAAGGCCGGGATGGTTTGGGTAAATACCTACAGATATATACGCTGGTCCACACCTTATGGAGGAATGA
AAGCGAGTGGCTGGGGGCGTGAAAACGGTCTGGAAGCGATGAGCCAGTATTTGGAAGTTAAAACCACCATTATGAGTACA
ACTAGTCGTTTCCCCAATGCTTATGCAGTAGAAAAGGAATAG

Protein sequence :
MLSYEKLFIDGAWVAPLDGSIEETINPATGKPWAKVAFGGARDIDKAVEAAKRALSGPWGKMTAIERGTLLRRLADLYQA
NANALAELETKDSGRALRESRMDVGSHHQWYRWFASVAETRRGNTIPIDDTVHAYTSEVPVGVVGAITPWNVPLMITAWK
LAPALAAGCTIVLKPAEQTPVTSLEFARLVEEAGFPPGVVNVVPGIGSIAGAALSSHRDVDKVSFTGEGQTAKTILQNST
GNMKRFSFELGGKAPHIIFEDADLEQAINAATNSSWALCGQSCALGARVLVQRSVYERVVEGFAERAKQVKVGNPSDPSI
HMGPQAHGEQLSKTLSYIQSGVDEGARLVSGGKCLTEGDLAGGFFIEPTVFADVSNNMKIAREEIFGPVACLIPFETEDE
AIAIANDSEFGLASGLWTRDMGRAHRVSSQIKAGMVWVNTYRYIRWSTPYGGMKASGWGRENGLEAMSQYLEVKTTIMST
TSRFPNAYAVEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-79 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-73 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-71 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-76 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-76 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-76 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hbal_2560 YP_003060932.1 betaine-aldehyde dehydrogenase VFG0082 Protein 1e-73 42