Gene Information

Name : fliI (Hbal_2221)
Accession : YP_003060598.1
Strain : Hirschia baltica ATCC 59814
Genome accession: NC_012982
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2376719 - 2378206 bp
Length : 1488 bp
Strand : -
Note : involved in type III protein export during flagellum assembly

DNA sequence :
TTGTCATATCTTGACATAAAGCGACTCGGTGAGGGTTCAGAACACGTGCTTCAACAGGCTATCAAAGATATTAAAAATAT
TGAAAAACAAATGTTTGAGGGTCGAGTTGTGGCTGTTGAAGGCTTGCGAATCGAAGCGACTGGACCTGCTGAAGCATTGC
GCTTAGGTGCTTATGCTCGCTTTGGAAACAAGGAAGGCCCGCGTGGTGAGCTAGTCGGATTTGAAGGTGAGCGCGCCGTT
TTCCTCGCATGTGATGATGTAGATGGTTTGCGCCCAGGGGCTGCAGTGTGTTTTTCTGCAGATGATGCAATTGTTAGGGT
GTCAAATTCTTGGTTGGGCCGCGTTGTTGATGCTTTTGGTGCGCCAGTTGATGGTGGTTTACCATTAGCGCAAGGCTCAA
TTTCGCGGCAAATTAAGGCTGTGCCACCTGCTGCGCACTCAAGAGCGCGGGTTTCTGAGCCGATGTCATTAGGAGTGCGA
GCACTTGATGGCTTTGCACCATGTGCAGTGGGACAGCGTATGGGCCTCTTTGCTGGATCGGGTGTGGGTAAATCAACTTT
GATGTCGATGCTGGCAAGGAATGCACAAGCTGATGTCGTGGTGATTGGCTTGATCGGTGAACGTGGCCGTGAGGTAAGAG
AATTTGTTGAAGACACACTAGGAATTGAAGGTTTGGCGCGTTCTGTTGTTGTGTCTGCTACATCGGATGAAACTGCGCCG
CGCCGTAGACGGGCGGCATGGATGACAATGGCGGTTGCTGAACATTTTAGAGACCAAGGTTATAAAGTGTTGTGTTTGCT
GGATTCCGTAACCCGTTTTGCGATGGCGCAAAGAGAGATTGGGTTGGCCGCAGGTGAACCGCCAACGACCAAAGGGTATA
CGCCATCTGTTTTTTCTGAACTTCCTAAATTATTAGAGAGAGCGGGGCCGGGGAAAATCGTACCAGCTGGACAGCCTCAA
GGCCAAATAACGGGTTTATTCACTGTGCTTGTGGATGGCGATGATCACAATGAGCCGGTCGCTGATGCCGTACGTGGTAT
TCTCGATGGGCATATTGTGATGGATCGTAAAATTGCAGAGAGAGGGCGCTATCCCGCGATAGATGTGCTTAAATCTTTGT
CACGATTGGCAAGCCATCTTTATACGCCAGAAACAGCAGAAATTGCGAGGCAGGCTCGCCGGTTGATGTCGCTTTATTCT
GATATGGAAGAATTGGTGCGGATTGGTGCATATGCGCGCGGGGCAGACCCAGAAGTGGACCGGGCTGTGCAGTTATCTCC
TGATATAGAAAAAATATTGACGCAGCATGTGAATGAAAATTCTCCTCCTGAGGAAACATTTGCGATGCTGGCTCAGGTTT
TGGGAATGAATGCTGAAGCGGCACCAAATCCACATATTCATGCCGCAGAAGCTGCGATGGCAGCGCAAGGGGGAGAGCGC
CGGAGTGAAAATCGGGCATCTCTCGCACGTCAATTAGGCGGCAATTAA

Protein sequence :
MSYLDIKRLGEGSEHVLQQAIKDIKNIEKQMFEGRVVAVEGLRIEATGPAEALRLGAYARFGNKEGPRGELVGFEGERAV
FLACDDVDGLRPGAAVCFSADDAIVRVSNSWLGRVVDAFGAPVDGGLPLAQGSISRQIKAVPPAAHSRARVSEPMSLGVR
ALDGFAPCAVGQRMGLFAGSGVGKSTLMSMLARNAQADVVVIGLIGERGREVREFVEDTLGIEGLARSVVVSATSDETAP
RRRRAAWMTMAVAEHFRDQGYKVLCLLDSVTRFAMAQREIGLAAGEPPTTKGYTPSVFSELPKLLERAGPGKIVPAGQPQ
GQITGLFTVLVDGDDHNEPVADAVRGILDGHIVMDRKIAERGRYPAIDVLKSLSRLASHLYTPETAEIARQARRLMSLYS
DMEELVRIGAYARGADPEVDRAVQLSPDIEKILTQHVNENSPPEETFAMLAQVLGMNAEAAPNPHIHAAEAAMAAQGGER
RSENRASLARQLGGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-63 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-63 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-63 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-63 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-63 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-68 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-67 46
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-67 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-67 46
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-67 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-67 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-67 46
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-67 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-65 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-65 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-52 46
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-62 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-49 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-49 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-53 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-54 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-54 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-48 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-56 43
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-56 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-61 43
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-61 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-56 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-61 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-56 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-56 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-56 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-56 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_003060598.1 flagellum-specific ATP synthase VFG0048 Protein 3e-69 48
fliI YP_003060598.1 flagellum-specific ATP synthase VFG2144 Protein 4e-65 47
fliI YP_003060598.1 flagellum-specific ATP synthase VFG0515 Protein 2e-63 47
fliI YP_003060598.1 flagellum-specific ATP synthase VFG2499 Protein 7e-66 47
fliI YP_003060598.1 flagellum-specific ATP synthase VFG0390 Protein 3e-68 45
fliI YP_003060598.1 flagellum-specific ATP synthase VFG1254 Protein 5e-63 45
fliI YP_003060598.1 flagellum-specific ATP synthase VFG2331 Protein 3e-66 45
fliI YP_003060598.1 flagellum-specific ATP synthase VFG0192 Protein 2e-65 44
fliI YP_003060598.1 flagellum-specific ATP synthase VFG0555 Protein 1e-56 42