Gene Information

Name : fliP (HELPY_0687)
Accession : YP_003057436.1
Strain : Helicobacter pylori B38
Genome accession: NC_012973
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : 3.1.1.3
Position : 667109 - 667855 bp
Length : 747 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence :
TTGCGTTTTTTCATTTTTTTCATTCTCATTTGCCCTTTAATATGCCCTTTAATGAGCGCTGATAGCGCTTTGCCTAGCGT
CAATCTCTCTTTAAACGCTCCTAATGATCCTAAACAGCTTGTAACCACCCTTAATGTCATCGCCCTGCTCACGCTTTTAG
TTTTAGCCCCGTCATTGATTTTAGTGATGACGAGTTTCACCCGTTTGATCGTGGTGTTTTCTTTTTTAAGGACCGCTTTA
GGCACGCAACAAACCCCACCCACTCAAATTTTAGTCTCGCTCTCTTTGATATTGACTTTTTTCATCATGGAACCTAGCTT
GAAAAAGGCTTATGATACAGGGATTAAGCCTTATATGGATAAAAAGATTTCTTACACCGAAGCGTTTGAAAAAAGCGCTC
TGCCTTTCAAGGAATTCATGCTTAAAAACACACGAGAAAAGGATCTAGCGCTTTTTTTTAGGATTAGGAATTTGCCTAAC
CCTAAAACCCCTGATGAGGTGAGCTTGAGCGTTTTAATCCCGGCGTTTATGATAAGCGAGTTGAAAACAGCGTTTCAAAT
CGGCTTTTTACTTTACTTGCCTTTTTTGGTGATTGATATGGTTATCAGCTCTATTTTAATGGCGATGGGCATGATGATGC
TCCCGCCCGTAATGATTTCTCTGCCTTTTAAAATTTTAGTGTTTATTCTGGTGGATGGGTTTAATTTATTGACCGAAAAT
TTAGTAGCGAGTTTTAAAATGGTTTAA

Protein sequence :
MRFFIFFILICPLICPLMSADSALPSVNLSLNAPNDPKQLVTTLNVIALLTLLVLAPSLILVMTSFTRLIVVFSFLRTAL
GTQQTPPTQILVSLSLILTFFIMEPSLKKAYDTGIKPYMDKKISYTEAFEKSALPFKEFMLKNTREKDLALFFRIRNLPN
PKTPDEVSLSVLIPAFMISELKTAFQIGFLLYLPFLVIDMVISSILMAMGMMMLPPVMISLPFKILVFILVDGFNLLTEN
LVASFKMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-22 46
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-22 46
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 8e-26 45
yscR NP_456109.1 putative type III secretion protein Virulence SPI-2 Protein 5e-25 45
yscR NP_805090.1 type III secretion system protein Virulence SPI-2 Protein 5e-25 45
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 1e-25 45
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 1e-25 45
escR AAK26700.1 EscR Virulence LEE Protein 3e-21 45
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 4e-21 45
escR AAL57527.1 EscR Virulence LEE Protein 3e-21 45
escR CAC81847.1 EscR protein Virulence LEE II Protein 3e-21 45
escR CAI43889.1 EscR protein Virulence LEE Protein 3e-21 45
escR AAC31528.1 L0049 Virulence LEE Protein 3e-21 45
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 4e-21 45
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 3e-21 45
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 4e-21 45
escR AAC38369.1 EscR Virulence LEE Protein 1e-20 45
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 4e-21 45
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 4e-21 45
unnamed AAL06354.1 EscR Virulence LEE Protein 6e-21 43
lscR AAO18040.1 LscR Virulence TTSS locus Protein 6e-24 42
YPO0270 YP_002345352.1 type III secretion system protein Virulence Not named Protein 1e-22 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG2338 Protein 6e-41 55
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG2016 Protein 1e-40 54
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG1259 Protein 1e-41 54
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG2494 Protein 1e-43 54
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG0519 Protein 5e-26 45
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG0715 Protein 8e-21 45
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG0827 Protein 2e-21 45
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG0044 Protein 1e-23 41
fliP YP_003057436.1 flagellar biosynthesis protein FliP VFG0394 Protein 9e-23 41