Gene Information

Name : tkt (HELPY_0365)
Accession : YP_003057158.1
Strain : Helicobacter pylori B38
Genome accession: NC_012973
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.-
Position : 361451 - 363376 bp
Length : 1926 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCGATTGAGTAACGCTGACTTGGAACGATTAAAAAGCATGGCGAATGCGCTTCGCTTTTTGTGCGCAGACATGATAGA
TAAGGCTAATAGCGGGCATCCGGGCGTGTGCTTAGGGCTAGCCGATGTGATGGTGGTTTTAAGCTTGCACCTAAACCTTA
ACCCCATTAACCCTAAATGGCTCAATAGGGACAGGTTGGTTTTTAGCGGAGGGCATGCGAGCGCGTTGGCGTATAGTTTG
TTGCATTTGTGGGGCTTTGATTTGAGTTTAGAAGATTTAAAGCGTTTCAGGCAATTGCACTCTAAAACCCCAGGACACCC
CGAATTGCACCACACCGAAGGCATTGAGATTACCACAGGCCCTTTGGGGCAAGGTTTTGCTAACGCTGTGGGTTTTAGCA
TGGCGAGCCAATACGCTCAAACCCTTTTAGATAAAGAAGCGATTTCCCATAAAGTCTATTGCTTGTGTGGGGATGGGGAT
TTGCAAGAAGGCATTAGTTATGAGAGCACTTCTTTAGCCGGGCACCTTCGCCTTGATAACCTCATTGTGATTTATGACAG
CAACCAAATTAGCATTGAAGGCACTATTGATATTAGTTTTAGCGAACAGGTTAAAATGCGGTTTGTGGCGCAAAATTGGG
AAGTGCTAGAATGCGATGGGCATGACTATCAAGCGATTCATAACGCTTTAGAAGAAGCCAAAAGATCCATTAAACCCACG
CTTTTAATCGCTCATACAATTATTGGTAAGGGAGCTGTTGGCTTAGAGGGAAGTGAAAAAACGCATGGCTCGCCTTTAAA
TAAAGAAGTGTTAAAACAATCCAAAGAAAACGCTCAAATCAATCCTGATGAAAGCTTTATCATTAGCCCAAAAAACAAAA
TGCATTTTGAAGAAGTGAAAGTTAGGGGCGTTAGCTTAGAAGCCTTATGGGAAAAATCCTTAAGCCCTAAAACAAAAGAA
AAAATCCATGCGTTAAAGGATTTTGATTTTAGCGCCATCCATTACCCCACCTTTAAAAAAGGCGAATCTCTAGCCACGAG
AGTGAGTAACGGCATGATTTTAAACGCTATCGCTAAAGAATGCGAGGGCTTTTTAGGGGGGAGCGCGGATCTAGCCCCCT
CTAATAACACGCATTTAAAACACTCTGGCGATTTCCCTTTAGGGCAAAACCTGCATTTTGGGATCAGAGAGCATGCCATG
GGGGCTATCACTAACGCTTTAGCGGCGTATGGTTTGTTTTTGCCTTTTTGTGCGACCTTTTTTGTGTTTAGCGATTATTT
AATGCCCAGCATGCGTTTGAGCGCTTTGATGAAACTAAAAGCCCTTTTTATCTTTACGCATGACAGCATTGGCGTGGGCG
AAGACGGAGCGACGCACCAGCCCATAGAGCAATTGAGCCATTTACGCGCTTTGCCTAATTTCTATGCTTTCAGGCCTAGC
GATGCTTTTGAAAATAAGGCTTGCATGCAAGTAGCGTTAAGTTTGAACGCTCCTAGCGCTCTTATTTTATCGCGCCAGAA
TTTGCCCGTGCTTGATGAGGTTTCTAAAGAGCAGGTTTTAAAAGGGGCGTATGTTAAACATGATTCTAAAGATCCCATTA
TCACGCTCGTTGCGAGCGGGAGCGAGGTTTCTTTGGCTTTAGAGAGCGCTAAAATTTTAGAGCGAGAAAATATCCCCACT
CAAGTGGTGAGCACGCCATGCTTTGATTTATTGATAGAGCAAGATGAAAGCTATCTTAAAGAACTCTTTAAGGGCAAAGT
CTTAGTCATTGAAGCGAGCCGTGCGATAGAGTGGTATCGTTTTGCGGATAAAATCATTGGCATGGATTCTTTTGGGAGCT
CAGCAAAGGGCGATAAACTCTTTGAAAAATTTGGCTTTAGCGTTGAAAACATCACCGCTCAAGCTAAAAGGTTGCTCAAC
GCATGA

Protein sequence :
MRLSNADLERLKSMANALRFLCADMIDKANSGHPGVCLGLADVMVVLSLHLNLNPINPKWLNRDRLVFSGGHASALAYSL
LHLWGFDLSLEDLKRFRQLHSKTPGHPELHHTEGIEITTGPLGQGFANAVGFSMASQYAQTLLDKEAISHKVYCLCGDGD
LQEGISYESTSLAGHLRLDNLIVIYDSNQISIEGTIDISFSEQVKMRFVAQNWEVLECDGHDYQAIHNALEEAKRSIKPT
LLIAHTIIGKGAVGLEGSEKTHGSPLNKEVLKQSKENAQINPDESFIISPKNKMHFEEVKVRGVSLEALWEKSLSPKTKE
KIHALKDFDFSAIHYPTFKKGESLATRVSNGMILNAIAKECEGFLGGSADLAPSNNTHLKHSGDFPLGQNLHFGIREHAM
GAITNALAAYGLFLPFCATFFVFSDYLMPSMRLSALMKLKALFIFTHDSIGVGEDGATHQPIEQLSHLRALPNFYAFRPS
DAFENKACMQVALSLNAPSALILSRQNLPVLDEVSKEQVLKGAYVKHDSKDPIITLVASGSEVSLALESAKILERENIPT
QVVSTPCFDLLIEQDESYLKELFKGKVLVIEASRAIEWYRFADKIIGMDSFGSSAKGDKLFEKFGFSVENITAQAKRLLN
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-96 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-87 41