Gene Information

Name : hemC (HELPY_0242)
Accession : YP_003057048.1
Strain : Helicobacter pylori B38
Genome accession: NC_012973
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 237234 - 238154 bp
Length : 921 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGGAAAAATTAGTGATTGGCTCTAGGGGGAGCGAATTGGCCTTATGGCAAGCGAATCACATTAAAGAACGCCTGAAAAA
AGAATGCTTGATAGAAAGCGAAATTCAAATCGTTAAGACTAAGGGCGATAAAATCTTAGACACCCCTTTAAATAAGATTG
GCGGTAAGGGGCTATTCACTAAGGAATTAGAAGAATTGCTTTTAAAAGGCGAAATTGATTTGGCGGTGCATTCTTTAAAA
GATGTGCCGGTCGTGTTTGAAAAGGGGTTAGACTTGGCATGCATCACCAAAAGGGCTGATGTGAGGGACACTTTTTTAAG
CGTGAAATTCCCTGATTTGATGAGTTTGCCTAAAGGGGCCAAGGTTGGCACGACTTCTTTAAGGCGTTCCATGCAGCTCA
AACTGAAACGCCAAGATTTAGACACAGAAAGCTTAAGGGGGAATGTCCAAACCCGTTTGAAAAAGCTTGAATGCGGTGAA
TTTGACGCTATCATTTTAGCTGAAGCCGGATTGTGCCGCTTAAATATTCAAGGAGCGAAATACCGCAAGGCTTTTAGCGT
AGAAGAAATGATTCCTAGCATGGGTCAGGGGGCTTTAGGGGTAGAAATGCTCAAAAACCACAAGCATTTTATTACGCTTC
AAAAACTCAACGATGAAGAAAGCGCGTTTTGTTGCCATTTAGAAAGGGAGTTTATCAAGGGGCTTAATGGGGGGTGTCAG
ATCCCTATAGGCGTGCATGCGAGTTTAATGGGTGATGGGGTTAAAATCCAGGCGGTTTTAGGCTTGCCTAATGGGAAAGA
AGTCATCACTAAAGAAAAGCGAGGGGATAAAACTAAAGCGTTTGATTTAATTCAAGAGCTTTTAGAAGAATTTTTACAAA
GCGGGGCTAAAGAGATTTTAGAAAAGGCGCAGTTGTTTTAA

Protein sequence : 
MEKLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGEIDLAVHSLK
DVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGE
FDAIILAEAGLCRLNIQGAKYRKAFSVEEMIPSMGQGALGVEMLKNHKHFITLQKLNDEESAFCCHLEREFIKGLNGGCQ
IPIGVHASLMGDGVKIQAVLGLPNGKEVITKEKRGDKTKAFDLIQELLEEFLQSGAKEILEKAQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-43 46
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-43 46