Gene Information

Name : serS (HELPY_1453)
Accession : YP_003058097.1
Strain : Helicobacter pylori B38
Genome accession: NC_012973
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1436841 - 1438088 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAGAAGACTTTTATTGCAAGATTTTGACAGGGTGGCTCTTTCTTTAAAAAAGCGTAATAATGCGATGGATGA
TACATTGGAGCGTTTGCGCGAAGTCATCACGCGTTATAAAAAGCGACTCATTGAATTAGAAGGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGCATCAAAATGGCTCAAAAAGCGGATGCAAGCGATCTCAAAAAAGAGCTAGAAAATAAT
AAAATCAAACTGAATGAGCTTTCCAAAAGCGTGGGCGAATTGGAGCAACAAATAGATTTAAAGCTTTCCATAATCCCTAA
TCTGGTGGATGAAAAAACCCCTTTAGGCGCAAGCGAAGAAGACAATATAGAGATTAAAAAAATCTTAACCCCAAGGGTTT
TCACTTTCAAACCCAAAGAGCATTTTGAACTCGCTCAACAAAATGGCTGGATTGATTTTGAAAGCGGCGTGAAACTCGCC
AAAAGCCGTTTTTCTGTCATCAGGGGTTTTGGGGCTAAAATTTATCGCGCGCTCATTCATTTGATGTTGGATTTTAATGA
AAAAAATGGCTTTGAAATCATTTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTACCCAAAT
TCAAAGAAGACGTTTTTAAAATAGAAAATGAAAATTTGTATTTGATCCCCACCGCTGAGGTAACGCTCACTAATCTATAC
AACGACACCATTATTAGCGTTGAAAACCTCCCCATTAAAATGACCGCGCACACGCCTTGTTTCAGGAGCGAAGCAGGGAG
CGCTGGCAAGGACACAAGGGGGATGATAAGACAGCACCAATTTGATAAAGTAGAATTGGTGGCTATCACGCACCCTACAG
AAAGCGATGCGATGCAAGAGCATATGCTAGAGAGCGCGAGCGAAATTTTAAAGGCTTTGGAATTGCCGCACCGGTTCGTG
CAATTGTGCAGTGGGGATTTAGGCTTTAGCGCGAGCAACACGATAGACATTGAAGTGTGGCTGCCCGGGCAAAATTGCTA
CAGAGAAATCAGCTCCGTGTCTAACACGAGGGATTTTCAAGCCAGGCGTGCCAAAATCCGCTTCAAAGAAAATCAAAAAA
ACCAATTAGCACACACCTTAAACGGCTCTTCTTTAGCGGTAGGCAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATCCACATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDRRLLLQDFDRVALSLKKRNNAMDDTLERLREVITRYKKRLIELEGLQAFQNKVSKEFGIKMAQKADASDLKKELENN
KIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTPLGASEEDNIEIKKILTPRVFTFKPKEHFELAQQNGWIDFESGVKLA
KSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPTESDAMQEHMLESASEILKALELPHRFV
QLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-78 46