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Name : metB (HELPY_0105) Accession : YP_003056932.1 Strain : Helicobacter pylori B38 Genome accession: NC_012973 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 107218 - 108360 bp Length : 1143 bp Strand : - Note : catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine DNA sequence : ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAGTGAGGATACGACAACGGGGGCGGTGAGCGTGCCTATTTATCA AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGTTTAGCCGGGATCCACGCC GTTTTTTCTCTCTTGCAATCAGGCGATCATGTGTTATTGGGCGATGATGTTTATGGGGGGACTTTCCGCTTGTTTAATAA AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATCTATCCCAAATCAAAAAGGCTATCAAGCAAA ACACTAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACCGATTTAGCGCAATGCGCTAGTGTCGCT AAAGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACGCCCTATTATCAAAACCCGCTTCTTTTAGGGGCAGA CATTGTGGTGCATAGCGGCACAAAATACTTAGGCGGGCATAGCGATGTGGTCGCTGGGCTTGTAACCACCAATAATGAAG CGTTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTGCTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA GGGATTAAAACGCTGGGATTGCGCATGGAAGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAATTTTTAGAAAAACACCC TAAAGTAGAAAAGGTTTACTACCCGGGCCTTCCCACTCACCCTAATTACGAGCTAGCTAAAGCCCAAATGCGTGGCTTTA GCGGGATGCTCTCTTTCACCCTCAAAAATGACAGCGAGGCGACTCTTTTTGTAGAAAGCCTTAAACTATTCATTTTAGGC GAAAGTTTGGGCGGGGTGGAAAGTTTGGTGGGGATTCCGGCATTTATGACCCATGCGTGTATCCCTAAAGAACAACGAGA AGCTGCAGGGATTAGAGATGGCTTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC AAGCGTTCGCTAAAATAGGCTAA Protein sequence : MRMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKQNTKALYLETPSNPLLKITDLAQCASVA KDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNYELAKAQMRGFSGMLSFTLKNDSEATLFVESLKLFILG ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 4e-97 | 55 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 3e-98 | 55 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 1e-72 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | YP_003056932.1 | cystathionine gamma-synthase | BAC0207 | Protein | 1e-63 | 44 |
