Gene Information

Name : Msip34_2617 (Msip34_2617)
Accession : YP_003052381.1
Strain : Methylovorus glucosetrophus SIP3-4
Genome accession: NC_012969
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2754765 - 2756648 bp
Length : 1884 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCACTGATAAAAACCTGAACAAATTCCTGAACGAGACCGCCGAAGTAGACGCGGGTGCGACGCAGCCATTTGC
CAAATCGCGCAAAATTTATGTGGAAGGCTCGCGCCCCGATATTCGCGTGCCTTTCCGCGAAATCTCGTTGTCCGACACGC
CATCGGCGTTTGGCGCAGAAAAGAATCCACCGGTTGTTGTGTATGACACCTCCGGCCCTTACACCGATCCTGATGTGAAG
ATCGACATCCGCAATGGCTTGCCCGCCCTGCGCGCTGGCTGGATTGCCGAGCGTAACGATACCGAGCAGCTGGATGGCCC
GACCTCTGACTTCGGCAAGCAACGCAAGGAAGACCCCAAGCTGGCTGAAATGCGCTTCAACCTGACGCGCAAGCCATTGC
GTGCCAAGCCCGGCATGAACGTGAGCCAGATGCACTACGCCCGCCGCGGCATCATCACCCCAGAAATGGAATACATCGCC
ATCCGCGAAAACCAGCGCCGCGAAAACATGAGCGAACTGCTGCAAACCCAGCACGCAGGTCAGCATTTCGGTGCCAGCAT
TCCCAAGGTGATTACGCCGGAATTCGTACGCGATGAAGTGGCCCGTGGCCGCGCGATTATCCCCGCTAACATCAACCACC
CTGAAATCGAGCCCATGATCATAGGCCGCAATTTCCTGGTGAAGATCAACGCCAATATCGGCAACTCCGCGCTGGGTTCT
TCGATCTCGGAAGAAGTCGAAAAAATGGTCTGGGGTACCCGTTGGGGTGGCGATACCGTGATGGATCTGTCCACCGGTAA
AAACATTCACGAAACCCGCGAGTGGATCATCCGTAACAGCCCGGTGCCGATTGGTACCGTGCCGATTTACCAGGCCCTGG
AAAAAGTCGACGGCAAAGCCGAAGACCTGACCTGGGAAATCTTCCGTGACACCCTGATCGAGCAAGCCGAACAAGGCGTC
GACTATTTCACCATCCACGCGGGTGTGCGTCTGGCTTACATCCCGATGACAGCCAAGCGCATGACCGGTATCGTGTCGCG
CGGCGGCTCCATCATGGCGAAATGGTGTCTGGCTCACCACAAGGAAAGCTTCCTATACGAGCATTTCGAAGATATCTGCC
AGATCATGAAGCAGTACGATGTTTCTTTCAGTTTGGGCGATGGCCTGCGTCCCGGCTCCATCTACGATGCCAACGACGAA
GCCCAGTTTGCCGAACTGAAGACGCTGGGTGAGTTGACCCAGATCGCCTGGAAGCACGATGTGCAGTGCATGATCGAAGG
CCCAGGCCACGTGCCCATGCACCTCATCAAGGAAAACATGGACCTGCAACTGGAACACTGTGGTGAAGCTCCGTTCTACA
CACTGGGACCATTGACCACCGATATCGCTCCTGGTTACGACCATATCACCTCCGGCATTGGCGCTGCCATGATCGGCTGG
TACGGTTGCGCCATGCTGTGCTATGTAACGCCCAAGGAGCATTTGGGTCTGCCAGACAAGGAAGACGTGCGTGTGGGCAT
CATCACCTACAAGATTGCTGCCCACGCCGCTGACTTGGCCAAGGGTCATCCCGGTGCGCAGATTCGCGACAATGCCTTGT
CCAAGGCACGTTTCGAATTCCGCTGGGAAGACCAGTTCAATCTTGGTCTGGATCCGGAAAAGGCCAAGGAATTCCATGAT
GAAACCCTGCCGCAAGAAGGCGCCAAGCAGGCGCACTTCTGTTCCATGTGTGGCCCGCACTTCTGCTCGATGAAGATCAC
GCAGGATGTGCGTGATTACGCCGACAAGCTGGGCGTGGATGAAAAAGAAGCCCTGAGCAAAGGCATGCAGGAAAAAGCGA
TTGAGTTCGTGAAGAAGGGCTCCGAGGTATATCAGAAGGTTTAA

Protein sequence :
MNATDKNLNKFLNETAEVDAGATQPFAKSRKIYVEGSRPDIRVPFREISLSDTPSAFGAEKNPPVVVYDTSGPYTDPDVK
IDIRNGLPALRAGWIAERNDTEQLDGPTSDFGKQRKEDPKLAEMRFNLTRKPLRAKPGMNVSQMHYARRGIITPEMEYIA
IRENQRRENMSELLQTQHAGQHFGASIPKVITPEFVRDEVARGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSALGS
SISEEVEKMVWGTRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEDLTWEIFRDTLIEQAEQGV
DYFTIHAGVRLAYIPMTAKRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICQIMKQYDVSFSLGDGLRPGSIYDANDE
AQFAELKTLGELTQIAWKHDVQCMIEGPGHVPMHLIKENMDLQLEHCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGW
YGCAMLCYVTPKEHLGLPDKEDVRVGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPEKAKEFHD
ETLPQEGAKQAHFCSMCGPHFCSMKITQDVRDYADKLGVDEKEALSKGMQEKAIEFVKKGSEVYQKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 75
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 75
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 73