Gene Information

Name : Msip34_1176 (Msip34_1176)
Accession : YP_003050950.1
Strain : Methylovorus glucosetrophus SIP3-4
Genome accession: NC_012969
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1253272 - 1254792 bp
Length : 1521 bp
Strand : -
Note : PFAM: Aldehyde Dehydrogenase; KEGG: mfa:Mfla_1995 lactaldehyde dehydrogenase

DNA sequence :
ATGAGTCTGGAAAGCTTGAAGGGCCTGGGTGTTGAGATTCCATATCAGGCCAAATATGACAATTACATTGGCGGTAAATG
GGTAGCTCCTGTAGACGGCGAATATTTCGATAACATCAGCCCGGTGACTGGCAAAGTGTTCTGCAAGGTCGCCCGCTCTA
ACGATAAGGACGTCAACCTGGCACTGGATGCGGCACATGCCGCCAAGGAAGCCTGGGGCAAGACCTCGACCACAGCCCGC
TCCAATATTCTGCTTAAAATCGCCGACGCGATGGAAGCCAACCTTGAAAAAATCGCGATTGCCGAAACCATAGACAACGG
CAAGCCCATCCGCGAAACCATGGCTGCGGACATCCCGCTCGCCATTGATCACTTCCGTTACTTTGCTGGCGCGGTGCGCG
CTCAGGAAGGCGGCATCAGCGAAATCGACCACGACACCATTGCCTATCACTTCCATGAACCACTAGGCGTTGTCGGCCAG
ATCATTCCCTGGAACTTCCCCATTCTGATGGCGGCATGGAAACTGGCACCAGCCCTGGCTGCTGGCAACTGTATTGTCAT
GAAGCCGGCCGAACAAACGCCAGCTTCCATTCTGGTGGTCATGGAAATCATCGGTCACCTGTTGCCACCCGGCGTGCTGA
ATGTGGTCAATGGTTTTGGCGTAGAAGCAGGCAAGGCGCTGGCCACCAGCCCACGCATCGCCAAGATCGCCTTTACCGGC
TCCACTTCCGTGGGTCGCCTGATCATGCAATACGCATCGCAAAACCTGATTCCAGTGACACTGGAACTGGGTGGCAAATC
TCCGAACATCTTCTTTGAAGACATCATGGACGCCGACGATGCTTACTTCGATAAATGTCTGGAAGGTTTCACCCTGTTTG
CATTGAATCAGGGCGAAGTCTGCACCTGTCCTTCGCGTGCCCTGATTCAGGAATCCATCTACGAGAAATTCATGGAGCGC
GCACTGAAGCGCGTCAAGGCTATCAAGCAGGGCAACCCGCTGGATGCTTCGACCATGATCGGTGCGCAGGCATCGAGCGA
GCAGGTCGAGATCATCATGTCCTACATCAAGCTGGGCCGTGAAGAAGGCGCAGAAGTGCTGACCGGCGGCAATGTCACCA
AGCTGGCTGGCGAACTGGGCGAAGGCTATTACATCGAGCCTACCGTGTTCAAGGGCCACAACAAGATGCGCATTTTCCAG
GAAGAAATCTTCGGCCCCGTGCTGTCGGTCACTACCTTCAAGGATGAAGCCGAGGCCCTGGCGATTGCCAATGACACCAT
GTACGGCCTGGGTGCCGGTGTGTGGACGCGTGATGGCAGCCGTGCCTTCCGCATGGGTCGTGGCATTCAGGCTGGCCGCG
TGTGGACCAACTGCTACCACCTCTACCCTGCCCATGCCGCCTTCGGTGGTTACAAGCAATCGGGTATCGGTCGTGAAAAC
CACAAGATGATGCTGGATCACTACCAGCAGACCAAGAACCTCCTGGTCAGCTACAACCCTAACGCATTGGGCTTTTTCTA
A

Protein sequence :
MSLESLKGLGVEIPYQAKYDNYIGGKWVAPVDGEYFDNISPVTGKVFCKVARSNDKDVNLALDAAHAAKEAWGKTSTTAR
SNILLKIADAMEANLEKIAIAETIDNGKPIRETMAADIPLAIDHFRYFAGAVRAQEGGISEIDHDTIAYHFHEPLGVVGQ
IIPWNFPILMAAWKLAPALAAGNCIVMKPAEQTPASILVVMEIIGHLLPPGVLNVVNGFGVEAGKALATSPRIAKIAFTG
STSVGRLIMQYASQNLIPVTLELGGKSPNIFFEDIMDADDAYFDKCLEGFTLFALNQGEVCTCPSRALIQESIYEKFMER
ALKRVKAIKQGNPLDASTMIGAQASSEQVEIIMSYIKLGREEGAEVLTGGNVTKLAGELGEGYYIEPTVFKGHNKMRIFQ
EEIFGPVLSVTTFKDEAEALAIANDTMYGLGAGVWTRDGSRAFRMGRGIQAGRVWTNCYHLYPAHAAFGGYKQSGIGREN
HKMMLDHYQQTKNLLVSYNPNALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-144 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-150 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-150 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-150 66
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-149 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msip34_1176 YP_003050950.1 aldehyde dehydrogenase VFG0082 Protein 1e-144 66