Gene Information

Name : Mmol_0558 (Mmol_0558)
Accession : YP_003047995.1
Strain : Methylotenera mobilis JLW8
Genome accession: NC_012968
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 591263 - 593854 bp
Length : 2592 bp
Strand : +
Note : KEGG: mfa:Mfla_2198 ATPase AAA-2; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase

DNA sequence :
GTGCGCTTTGATAAATTAACCACTAAGTTCCAACAAGCGATTAGCGACGCACAAAGCTTGGCTTTGGGCGCTGATAATAC
CGCGATTGAATCACAACATTTGTTACAGGCATTGCTGCAGCAAGAAGACGGCGGTACTGCATCGCTATTGGCCCGTGCTG
GAGTGCAGCTGAATCAACTGAAAACGGGCTTGACGGCAGCCATTGCCAATTTACCTAAATCAACAGATACCAGCGGCGAG
GTGGCGATTTCTCGTGATTTAAATAATCTGCTGAATGTGACCGATAAGCTGTCACAAAAACGCGGCGACGCTTACATCGC
TAGCGAAATGTTCTTGTTAGCTTTGGCTGATGATAAAGGTGAAACTGCGAAGTTGCTTAAACAAAATGGCCTGACTAAAA
CTGCACTAGAAGCTGCCGTGCAAGCAGTGCGTGGCAATGAAAATGTGGATAGCCAGGAAGCTGAAGGTCAACGTGAGTCG
CTGAAGAAATATACGATAGATTTAACGGAGCGTGCGCGCCTTGGTAAGCTAGACCCTGTCATTGGTCGCGATGATGAGAT
ACGCCGTGCGATACAAGTATTGCAGCGCCGAACCAAAAACAACCCGGTACTGATTGGTGAGCCGGGCGTTGGTAAAACTG
CCATTGTGGAAGGCTTGGCGCAGCGTATTGTCAATGGTGAGGTGCCTGAGTCACTCAAAGGAAAAAAAGTATTGTCATTG
GATATGGCAGCTTTACTGGCGGGTGCCAAATACCGCGGTGAGTTTGAAGAGCGCTTGAAGTCTGTATTGAAAGAGCTAGC
GCAGGATGAAGGCCAAACCATCGTGTTTATTGATGAAATTCATACCATGGTTGGTGCAGGTAAAGCCGAAGGTGCGATGG
ACGCGGGCAATATGCTGAAGCCGGCTTTAGCGCGCGGTGAATTGCACTGCGTGGGCGCGACCACTTTAGACGAATACCGC
AAATATATTGAAAAAGACGCAGCACTGGAGCGCCGTTTCCAAAAGGTATTGGTGGATGAGCCTAGCGTAGAGGCAACCAT
CGCTATTTTACGTGGCTTACAAGAGAAGTATGAGCTACATCATGGGGTGGAAATTACCGACCCTGCCATTGTGGCCGCAG
CCGAGTTGAGCCATCGCTATATTACCGACCGTTTTTTACCCGATAAAGCCATTGATTTAATTGATGAAGCGGCAAGCCGC
ATCAAGATGGAAATTGACTCTAAACCAGAGGTGATGGATAAATTGGAGCGCCGTTTGATTCAACTCAAAATTGAGCGTGA
AGCGGTGCGCCGTGAAAAAGATGAGGGCAGTAAAAAGCGCTTTGAATTGATTGAAGATGAAATCAGCAAGCTGGAAAAAG
AGTATGCTGATTTAGAAGAAATCTGGAAATCAGAAAAAGCGCAGGTACAGGGCTCTGCACACATTAAAGAGGCGATTGAA
AAAGTAAAATTTGAGATGGAAGAAGCCACGCGTAAGGGCGACTGGCAGAAAGTCTCTGAGTTGCAGTATGGCAAGTTGCC
TCAACTGGAAACGCAATTGAAGCAGGCATCTACCGCTGAAGTGAGTGTAGATTTAAGCAAACACAAAATGCTGCGCACGG
AAGTGGGCGCGGATGAGATTGCTGAGGTGGTCAGTCGCGCTACGGGTATACCTGTGAGCAAGATGATGACCGGTGAGCGT
GAAAAATTGCTGACTATGGAGGCGAAGCTGCACGAGCGCGTGGTGGGGCAGGATGAAGCAGTGCGTCTGGTGTCGGATGC
GATTCGTCGTTCCCGTTCTGGTTTAGGTGATCCGAATCGGCCTTATGGCAGCTTCTTGTTTTTAGGTCCTACCGGCGTGG
GTAAAACTGAGCTATGCAAATCTCTTGCTAACTTCTTGTTTGATTCAGAAGAGCACCTGATTCGTATCGACATGAGCGAG
TTCATGGAGAAACACTCGGTTGCTCGTATGATAGGTGCGCCTCCAGGTTATGTGGGTTATGAAGAAGGTGGCACCTTAAC
TGAGGCGGTGCGTCGCAAACCTTACAGCGTGATTTTGCTGGACGAGGTGGAGAAGGCGCATCCGGATGTATTTAATGTGC
TGCTGCAAGTACTAGATGATGGCCGCCTGACCGATGGCCAAGGTCGTACTGTGGATTTTAAAAACACCGTCATCATCATG
ACCTCTAACCTTGGCAGTCAAATGATACAAAGTATGAGCGACCAAGACTACCAACTGGTGAAATTGGCGGTGATGGGCGA
GGTTAAAACGCATTTCCGTCCGGAGTTTGTGAACCGGATTGACGAAGTTGTTGTGTTCCATGCCTTAGGCGAAGAGAACA
TTAAATCGATAGCGGCTATTCAGTTGCAATACTTGGCGAAACGCTTGGCTGCAATGGATATGCAACTCGAGTTGACGGAC
GCTGCGATTGCCGAAATTGCGAATGCCGGGTTTGACCCTGTGTATGGTGCGCGGCCATTGAAACGTGCAATTCAGAGTGA
GATTGAGAACCCGTTGGCGCGTGAAATCTTGGCAGGGAATTTTATTGCCAAAGACACTGTCAAAATCGACGTGAGGGCTG
GGAAGCTGGTATTTTCAAAAGCAACGGTTTAA

Protein sequence :
MRFDKLTTKFQQAISDAQSLALGADNTAIESQHLLQALLQQEDGGTASLLARAGVQLNQLKTGLTAAIANLPKSTDTSGE
VAISRDLNNLLNVTDKLSQKRGDAYIASEMFLLALADDKGETAKLLKQNGLTKTALEAAVQAVRGNENVDSQEAEGQRES
LKKYTIDLTERARLGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLKGKKVLSL
DMAALLAGAKYRGEFEERLKSVLKELAQDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASR
IKMEIDSKPEVMDKLERRLIQLKIEREAVRREKDEGSKKRFELIEDEISKLEKEYADLEEIWKSEKAQVQGSAHIKEAIE
KVKFEMEEATRKGDWQKVSELQYGKLPQLETQLKQASTAEVSVDLSKHKMLRTEVGADEIAEVVSRATGIPVSKMMTGER
EKLLTMEAKLHERVVGQDEAVRLVSDAIRRSRSGLGDPNRPYGSFLFLGPTGVGKTELCKSLANFLFDSEEHLIRIDMSE
FMEKHSVARMIGAPPGYVGYEEGGTLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIIM
TSNLGSQMIQSMSDQDYQLVKLAVMGEVKTHFRPEFVNRIDEVVVFHALGEENIKSIAAIQLQYLAKRLAAMDMQLELTD
AAIAEIANAGFDPVYGARPLKRAIQSEIENPLAREILAGNFIAKDTVKIDVRAGKLVFSKATV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-147 42
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-109 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mmol_0558 YP_003047995.1 ATP-dependent chaperone ClpB VFG0079 Protein 0.0 47
Mmol_0558 YP_003047995.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-119 41