Gene Information

Name : hemC (Mmol_0166)
Accession : YP_003047603.1
Strain : Methylotenera mobilis JLW8
Genome accession: NC_012968
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 178308 - 179249 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCAAAACTCAAAATTACACACACCGCCTAAAAAATTAGTGATTGCTTCGCGCGAAAGTGCGCTTGCCATGTGGCAGGC
TCGCCATATTCAAAGTCGCCTGCAAGCACTTTACCCTGAAACAGAAGTCACTATTTTGGGGATGACCACCACCGGTGACC
AAATCCTAGATACGCCCTTAGCCAAAGTAGGCGGTAAAGGGTTATTTGTAAAAGAATTAGAAATCGCGCTAGCCGATGGC
CGCGCAGACCTGGCCGTCCACAGCATGAAAGATGTGCCGATGAACCTACCAGAAGGCTTTATCCTTGCCGCAACCGGCGA
GCGTGAAGATCCACGTGATGCGTTTGTGTCTAACGACTATGCCACGCTGGAAGACCTGCCTGCCAACAGCATCGTGGGCA
CATCCAGCTTACGCCGCCAAAGCCAGTTGCAGGCACGCTTTCCACACTTAAAAATCGAGTCGCTACGCGGCAACCTGCAA
ACCCGTCTGCGCAAGCTGGACGAAGGTCAGTATGCAGCGATTATTCTGGCAGCCGCTGGCTTAATTCGCCTCGAACTAGG
CAACAGGATTCGTCAATTCATCGCACCTGAGCATAGTATTCCCGCGGTGGGACAAGGCGCATTAGGCATAGAAATCAGCG
CAGACCGCCCTGACCTCATTGCCACACTCGCCCCGCTTAATCACCCGGATACGCAAGTATGCGTAGAAGCCGAGCGCGGC
ATGAGCCGCTCCCTTGCCGGCAGCTGCACCGTGCCGCTAGGCGCTTACGCAGTATGTGAGGCAGATAGCATCCGCATCAC
AGGGTTTGTAGCCAGTGTCGATGGCAAACAAATGCTGATAGAAACCGCGGTTGGCAGCAGAGCCAATGCTGAAGCACTAG
GCAAAACGCTGGCCAGCCAATTAGTCGCCAAAGGCGCAGATAAGATTCTCGCTGCCCTGTAA

Protein sequence :
MQNSKLHTPPKKLVIASRESALAMWQARHIQSRLQALYPETEVTILGMTTTGDQILDTPLAKVGGKGLFVKELEIALADG
RADLAVHSMKDVPMNLPEGFILAATGEREDPRDAFVSNDYATLEDLPANSIVGTSSLRRQSQLQARFPHLKIESLRGNLQ
TRLRKLDEGQYAAIILAAAGLIRLELGNRIRQFIAPEHSIPAVGQGALGIEISADRPDLIATLAPLNHPDTQVCVEAERG
MSRSLAGSCTVPLGAYAVCEADSIRITGFVASVDGKQMLIETAVGSRANAEALGKTLASQLVAKGADKILAAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-71 58
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-71 58