Gene Information

Name : thyA (Mmol_1531)
Accession : YP_003048962.1
Strain : Methylotenera mobilis JLW8
Genome accession: NC_012968
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1679970 - 1680764 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATACATCGACTTAGTGCAACATGTGTTTGAGCATGGCAATAAAAAAGAAGACCGCACCGGTACCGGTACAGT
TTCTGTATTTGGCTACCAAATGCGCTTCAATCTGGCAGAAGGTTTTCCTCTTCTTACCACTAAAAAAGTACACTTAAAGT
CGATTATTCACGAATTGCTCTGGTTTCTACAGGGCAGCACCAATATTGCATACCTAAAAGAAAACGGCGTACGCATCTGG
GACGAGTGGGCTGATGAAAATGGTAACCTAGGCCCGGTATATGGCTACCAATGGCGCAACTGGCCTAAGCCAGATGGTTC
GCATATCGACCAGATTGCACAAGTGGTCAATAGTATTAAAAATAACCCGGATTCACGTCGCTTAATCGTTTCAGCTTGGA
ACGTAGCGGACGTGGATCAAATGAAACTTCCGCCTTGCCATGCATTCTTTCAGTTTTATGTAGCTAATGGTAAGTTGAGC
TGCCAATTATATCAACGTAGTGCCGATATCTTCTTGGGGGTGCCTTTTAACATCGCTTCATATGCTTTGCTCACGATGAT
GGTAGCGCAGGTTTGTGGCCTGAAATTAGGCGATTTTGTGCATACGCTGGGCGATGCGCATATTTACTCGAACCATTTTG
AGCAAATGCATGAGCAGTTGCAACGTGACCCACGACCATTGCCAACTATGCGTATCAACCCAGAAGTAAAAGATATTTTC
AGCTTTAAGTTTGAAGATTTCACCTTAGAAGGGTATGATCCGCACCCCCCAATTAAAGGCCAAGTCGCTGTTTAA

Protein sequence :
MKQYIDLVQHVFEHGNKKEDRTGTGTVSVFGYQMRFNLAEGFPLLTTKKVHLKSIIHELLWFLQGSTNIAYLKENGVRIW
DEWADENGNLGPVYGYQWRNWPKPDGSHIDQIAQVVNSIKNNPDSRRLIVSAWNVADVDQMKLPPCHAFFQFYVANGKLS
CQLYQRSADIFLGVPFNIASYALLTMMVAQVCGLKLGDFVHTLGDAHIYSNHFEQMHEQLQRDPRPLPTMRINPEVKDIF
SFKFEDFTLEGYDPHPPIKGQVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-83 64