Gene Information

Name : PAU_02302 (PAU_02302)
Accession : YP_003041138.1
Strain : Photorhabdus asymbiotica ATCC 43949
Genome accession: NC_012962
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1020
EC number : -
Position : 2616773 - 2622868 bp
Length : 6096 bp
Strand : +
Note : similar to hmwp2 protein of yersinia enterocolitica

DNA sequence :
ATGCACACGGACCTTCACTCCCCAGATTCGCTGCGTCAGCTCATATCTGACCTGTTTAATCAAAAAAATATTTTGGTGGA
CGATAACGATGATTTAATTCGCAATGGACTGGATTCAATGCAAATCATGGCATTGTTAAACCAGTTTAGACGTCAGGGAC
ATCGCGTCACTCTGCGCGAACTTTACCAAAAGCCAACATTGCACGCCTGGAGCCAGCTTCTACAACGTCATGCACCTGTC
GCTCACACCGCGCCCAAAGATACAACGCCACAACCACTGATTGTAGATGCGCGCCCATTCCCATTGACGGCAGTACAACA
TGCTTACTTTGTTGGACGTTCACCAGAACAAACGTTGGGGGGAGTTGGTTGCCATTTGTATCAAGAGTTCGATGGCGTGG
GTCTGGAACCTGAACAACTGGAAGCTGCGATTCATGTGCTGATTCAGCGGCATCCGATGTTGCGCGTGCGGTTTTTGTCA
GATGGTCGCCAGCAAGGTATGACCCGTGTTGACTTGAAAAAATTAACTGTTCATGACCTGCGCAATCTGACAACTAATGA
GCAACAACAAGCGTTGAACAACCTACGTGAACAACTGAGCCACCGAGTATTACAGGTTGAAGAAGGGGAAACTTTCGATA
TTCAGCTTAGCCTGTTTGGTGATAATCAACACCGGCTGCATGCCAATATTGATCTACTGATCATGGATGCCGCCAGTTTC
AGTCTATTTTTCACCGAACTGGCAGCATTAATTGCCAAACGCAACCTGCCCGCTATTTGTTCCGACTATGATTTTTGCAG
TTATCTAACACAGTATCAGGCCCAATTTAAACAGGCTCGGCAAGAAGCAGAGGTGTTTTGGCGCAACCGGTTAGACACTT
TGCCGCTTGCCCCTCAGCTGCCTTTGGCTCGGGACCCTTCCCTAATAAAAAATGTTCATATTCAGCGCAGATGTTTCCGT
TTAGCGCCTGAACATTGGGAACGATTTAAACAACTCGCGCAGCAAAATGGTGTTACGCCAACTATGGCACTCGCGACCGC
ATTTGCCGCTTTATTATGTCGCTGGAATAATGCAACGCGCTTGTTGTTCAACCTGACGCTATTTGACAGAGCGCCACTAC
ATACCGCGGTTGACAACATGCTAGCCGATTTTACCAACATTCTGCTGTTAGACATTCCTGGTGATAATTTACCGTTCTGC
CAACTGGCTCAGGATGCGCAAGCTACCTTTGCCGAAGCTTACGAACATCGTCACTGGTCTGGTGTAGAAGTTTTACGTGA
ACTCAAGAAACGAGGTAGCCACCCACACGGCGCGCCAATTGTATTTACCAGCAATTTAGGTCGACCTTTATATGGTGAAA
ATACCCGTGATGTACTGGGAAAACCAAGTTGGGGAATATCACAAACCCCTCAGGTATGGCTGGATTTCGTTTCCTTTGAA
CATGAAAACTCGCTGAATATTCAGTGGGATAGTAATGATGAACTCTTCCCTGACGGCTTAATGGATACCTTATTCACGGC
CTATCAGGGGCTGATTGAGAACCTGACGGAAAACGCCGCGCAGTGGAACGAAAAGCTACCGGATCTGATGCCTGAGTCGC
AGTATCATCTGCGACGCCAAATCAATAACACGGTTGAACCCCTACCAAATGCTCTGCTGCATGAGGGCGTGTTCATACAA
GCAGAACGTACACCAAATGCTGTGGCTTTGGTGACTCATCATAAAAAAATGAGTTATGGCGAATTAAGTCTGGCCGCCCG
CCAGTTAGCTGCCGTACTGCAAAAAATGCCAGTGATGCCGGGAGACCGGGTTGCTATTAGCATGGAAAAAGGTATCGGAC
AAATTGTCGCCGTATTAGCCATACTTTACGCCGGCGGTGTCTACGTTCCAGTTCCCGTTGATCAACCATTAAACCGACGA
CGTACTATCTGTGAAAGTGCCGGGATCAATGTCGTTATCATTGATCCTGAACAACAGAATGATGACTGGTCACAAGATAT
ACATTGCATTTCCTGGCATCAGGATGCTCAATTACCTCCTTTAGCAAACATGTCCAAACGCGCGGTTACTGATCCGGCGT
ATATTATCTATACCTCTGGTTCAACGGGGATGCCAAAAGGTGTGGTTATCAGCCACCAAAGCGCACTCAATACCTGTCTG
GACATCAATCGCCGTCATCAGGTTCAAAGTCATGACCGGTTACTGGCACTCTCAGCCCTGCATTTCGACCTCTCTGTTTA
TGACATTTTTGGCATTCTCAGTGCTGGAGGTGCACTGGTATTAATTAACGAAGCCCAACGCCGCGACCCATCAACTTGGG
AAATGCTGATCGCGCAACATAACGTTACATTGTGGAACAGCGTACCGGCGCTGTTTGATATGTTGCTGACCTATTGTGAA
GGAATGGAAGTAGATGCGCCGAAAGCGCTTCGTACCGTGATGCTATCTGGGGACTGGATCGGCTTATCACTGCCTGAGCG
TTACCGTGCATTCAATCCTGATGGTGTATTAAGTGCTATGGGCGGCGCAACGGAGGCTGCTATCTGGTCAAATGAATATA
TCGTCAAACAAGTTGACGCACAGTGGCGCTCTATTCCTTATGGTTATCCTTTGGCTAACCAGCGTTACCGTGTCGTTGGT
GAAGATGGTCGTGATTGCCCTGACTGGGTTGTCGGTGAACTTTGGATTGGTGGTGCCGGTGTAGCATTAGGCTATTTTAA
TGATGAAGAGCGCACTTCTGCCCAATTCGTCGTCGATCAAGGAGAACGCTGGTACCGTACTGGTGATCTAGGCTGTTACC
ATCCCGCAGGCTGGCTTGAGTTTATGGGACGTCGCGATAGCCAGGTAAAAATCGGTGGATACCGAATTGAGTTAGGAGAG
ATTGATGCTGCCCTGAATCAGGTAACCGGAATCAGTAAAGGGGTTGCCTTAGCCAGTGGCGAAAAAGAGAAATCGCTGGT
GGCATTCCTTGAATTGGAAGGCGATACTTTATGCCAACGCGTCAATCGTGCACCACAATTACCCATAAGCTACCGTGATC
TGTTTCCCACCGCTCAGGCAATAACCGATAACAGCCATGACCCTCAGGTTGCCATATTTCTGTTAGAACATTTGTCTCGT
CACGGTATGACGTTTACTGCACCTCAATCGCTCACCGATTGTCTGAAACACTATCAGCCTCAACCGGAATATCATGACTG
GTTTGGCCGTATGCTGGCATACCTTTGTCAATGCAAGCTATTAGCTGAATCTACACATCATGTCTATCAGGCCGTATCGC
CAGCCACGACATTCAATAATGAAGCAGGATGCATCCCAGAACGCTGGCACTCTATGCTACGTAGCATTCTTACCGGGCAA
CAGGCCGCAGTTACATTACTTGATGATCCGCAATTCGCGCCAGAACAGCAGCTCTTCGTACTACCAGAAACCCAGCAATG
GTTAGCAGGACTAAAACAGGTAATCATTGCCCTTTCCCAACGGTTACAACGCCCTATTACGTTGATGGAGTTTGACGCCC
GTAGCGGCCTCTGTGCTCAGTGGCTAGCAGAACATATCACTGACCAACATCTGTCTTACCTCGGGTTTGAACGTTCCCAA
GCCCTGATCAATCAGGCGCAAACACGGTTAAGCGGTTATGCCCACGCATCAGTACATCATTGGCTTGAACAAATTCCAGA
GTCGCTACAGCATCAGGCCGATATCATCCTGCTAAACAATGTCTTACACCGCGAGGGAGATCCTGCAAATTGCATCAAAG
CGTTAATGCCTCTGGCACAACCCGGTGCGCTGGTGTTGGCAATGGAGTTGCAACAAGCCTCATCTCTCTCCCTGATTACG
ACTGAGTTGTTATCACCTCACGGTATTCAGCTACGTTCTGCGTCACAGTGGTTGCCTCTTTTACCACTACAGGCGGAAAC
ACCCATTACCATCGGTAATCTTAGTGTGTTGTTGATGCAGGCAAGTGACAACGTCACCCTTCCTGATCGGGAAAAAATTA
AATCCGTATTGGCGCAACATTTGCCGGGATATATGATCCCACAGCGTTTACATGTTATTCCGCGTCTGCCTCTGACACCT
AACGGCAAAATTGATCGGAAGGTGCTGTCACAAGCCCTGCAATCCACGACAAAAACAGACGTGTCACACCAGAATGAAAT
GACCTCGTTGAATCCGGTAGAACAAACCGTTGCCAACCTCTGGCAACGCCTGCTAAATACAGAGCAATTAGGCCGTCATA
GTGACTTTTTCCAACTTGGCGGTGATAGTCTTCTGGCTACACGTCTGATTGGTGAATTGACACAACAAGGCTTCAAAGGC
GAACTTGGACATCTTTTCCGTAACCCGCAATTGGCAGAGTTTGCTGCTACACTGGCGCCTCTGTCTGAAACTGCATCAGA
AACCTATTCAATACCAAAAGAGCAAGATGAATATCAGCCTTTCCCATTAACCGAAGTTCAGCAAGCTTATTTGGTTGGAC
GCCATCCCGGTTTTGCCCTCAGTGGTGTTGGTGCTCATTTCTTTATCGAATACCGGCTAGAACAGTTAGATGTTCAACGA
CTGAACCGGGTATTAAATCGCCTGATCCAGCGCCATCCTGTGCTTAGAACTATTGTGATTAATGGACAGCAGCAGGTATT
GAAAGATGTCCCGATGTTCTCCGTTAAACAACACCAATTCACGGATATTACGCAGGCAGACACACTACGCGAACGTCTGT
CACATCAGGTATTAGACGCCAGTCACTGGCCGGTGTTCGATTTCCAACTTGCTCAAGACAACAGCCTTGTCTCCCGATTA
TTTGTCAGCCTGGATAATTTGCTATTGGACGGGTTGAGCATGCAGATATTGCTGGCTGAATTAGAACAGCTATATCTCAA
CGAACAGTACGAATTGCCGCCACTGAAAGTCACATTCCGGGATTGTGTGTTACGCCAGCAACAAACGCCGGCACATCAGA
ACTCACTGCAATATTGGCAGGAGCAAGTGAAAACATTACCACTGGCCCCGCAATTACCATTACGTATTGCACCGGAAGAT
GTTCAATCTCCGCGTTTTGTGCGCTACAGCGATCGGTTATCTGCACATGAATGGAATCAGTTAAAGCAACATGCTGCCTC
CCATCAGATAACCCCTTCGGCGCTCTTAATTGCGGCTTATGCGGCTGTTTTGTCCGCATTCAGCGCCAGACCGGAGTTAA
CCCTTAATCTTACCCTTTTCGATCGTCCGCATTGGCATGAGGACATTAATCACATTCTGGGTGATTTCACTTCACTGTCA
TTACTGGCCTGGCATCCAGAGAAAAATTGGTTATTAAGCGCCCGACGACTGCAACAACAATTATGGCAGGATCTGGATCA
CCGCCATATTTCAGCTATCAGAGTGATGCGTGAACTGGCACAGAGCCGTGGTCCCGATGCAGCTATTATGCCAGTCGTTT
TCACCAGTGCATTGGGAACACATGAAGGACGATTCCTTTCACGTTCATCATGGATGAAACCGGTTTGGGGTATCTCACAA
ACGCCACAAATCTGGTTGGATCATCAGGTTTACGAATCTGACAATGAGCTTTGCCTAAACTGGGATGCTGTCGAAGAGTT
ATTTGAACCGCATCAGTTACAAAACATGTTCAATAGCTATATGGCACTCTTGCGTACCCTTGCTGCACAACCAGAAAGCT
GGCATTCAGCATTGGAACAACTGATGCCACGCCAGCAATGCACCATAGTTGGAGATAACGCCGCTGTTGTTATTGCGTCA
TCACCACGTTCGGAAGGACTCGATCCACAAATATGCAATGAAATTCAACGCCTGTTTTTATCGGTAACAAATCATCCTAT
TAATGCACAACAAAACTTTTTTGAGGCAGGAGCCAACTCGCTACAGTTAATTCAACTGCATAGCAAATTACAACATGCGG
GTTTCCATCATCTTGCCGTTACTGATTTATTCGCTTATCCAACACCAGAGACGCTCAGCTTGCGCTGCCGAAAGGATGCC
CACGACGGAAATCGCCAGTCGATTACCCCTCGTCAGCGCCAACAACAAAAGCGTCTGCAACAACGGGAAAAACGTCATAA
AGGAGCTGCACAATGA

Protein sequence :
MHTDLHSPDSLRQLISDLFNQKNILVDDNDDLIRNGLDSMQIMALLNQFRRQGHRVTLRELYQKPTLHAWSQLLQRHAPV
AHTAPKDTTPQPLIVDARPFPLTAVQHAYFVGRSPEQTLGGVGCHLYQEFDGVGLEPEQLEAAIHVLIQRHPMLRVRFLS
DGRQQGMTRVDLKKLTVHDLRNLTTNEQQQALNNLREQLSHRVLQVEEGETFDIQLSLFGDNQHRLHANIDLLIMDAASF
SLFFTELAALIAKRNLPAICSDYDFCSYLTQYQAQFKQARQEAEVFWRNRLDTLPLAPQLPLARDPSLIKNVHIQRRCFR
LAPEHWERFKQLAQQNGVTPTMALATAFAALLCRWNNATRLLFNLTLFDRAPLHTAVDNMLADFTNILLLDIPGDNLPFC
QLAQDAQATFAEAYEHRHWSGVEVLRELKKRGSHPHGAPIVFTSNLGRPLYGENTRDVLGKPSWGISQTPQVWLDFVSFE
HENSLNIQWDSNDELFPDGLMDTLFTAYQGLIENLTENAAQWNEKLPDLMPESQYHLRRQINNTVEPLPNALLHEGVFIQ
AERTPNAVALVTHHKKMSYGELSLAARQLAAVLQKMPVMPGDRVAISMEKGIGQIVAVLAILYAGGVYVPVPVDQPLNRR
RTICESAGINVVIIDPEQQNDDWSQDIHCISWHQDAQLPPLANMSKRAVTDPAYIIYTSGSTGMPKGVVISHQSALNTCL
DINRRHQVQSHDRLLALSALHFDLSVYDIFGILSAGGALVLINEAQRRDPSTWEMLIAQHNVTLWNSVPALFDMLLTYCE
GMEVDAPKALRTVMLSGDWIGLSLPERYRAFNPDGVLSAMGGATEAAIWSNEYIVKQVDAQWRSIPYGYPLANQRYRVVG
EDGRDCPDWVVGELWIGGAGVALGYFNDEERTSAQFVVDQGERWYRTGDLGCYHPAGWLEFMGRRDSQVKIGGYRIELGE
IDAALNQVTGISKGVALASGEKEKSLVAFLELEGDTLCQRVNRAPQLPISYRDLFPTAQAITDNSHDPQVAIFLLEHLSR
HGMTFTAPQSLTDCLKHYQPQPEYHDWFGRMLAYLCQCKLLAESTHHVYQAVSPATTFNNEAGCIPERWHSMLRSILTGQ
QAAVTLLDDPQFAPEQQLFVLPETQQWLAGLKQVIIALSQRLQRPITLMEFDARSGLCAQWLAEHITDQHLSYLGFERSQ
ALINQAQTRLSGYAHASVHHWLEQIPESLQHQADIILLNNVLHREGDPANCIKALMPLAQPGALVLAMELQQASSLSLIT
TELLSPHGIQLRSASQWLPLLPLQAETPITIGNLSVLLMQASDNVTLPDREKIKSVLAQHLPGYMIPQRLHVIPRLPLTP
NGKIDRKVLSQALQSTTKTDVSHQNEMTSLNPVEQTVANLWQRLLNTEQLGRHSDFFQLGGDSLLATRLIGELTQQGFKG
ELGHLFRNPQLAEFAATLAPLSETASETYSIPKEQDEYQPFPLTEVQQAYLVGRHPGFALSGVGAHFFIEYRLEQLDVQR
LNRVLNRLIQRHPVLRTIVINGQQQVLKDVPMFSVKQHQFTDITQADTLRERLSHQVLDASHWPVFDFQLAQDNSLVSRL
FVSLDNLLLDGLSMQILLAELEQLYLNEQYELPPLKVTFRDCVLRQQQTPAHQNSLQYWQEQVKTLPLAPQLPLRIAPED
VQSPRFVRYSDRLSAHEWNQLKQHAASHQITPSALLIAAYAAVLSAFSARPELTLNLTLFDRPHWHEDINHILGDFTSLS
LLAWHPEKNWLLSARRLQQQLWQDLDHRHISAIRVMRELAQSRGPDAAIMPVVFTSALGTHEGRFLSRSSWMKPVWGISQ
TPQIWLDHQVYESDNELCLNWDAVEELFEPHQLQNMFNSYMALLRTLAAQPESWHSALEQLMPRQQCTIVGDNAAVVIAS
SPRSEGLDPQICNEIQRLFLSVTNHPINAQQNFFEAGANSLQLIQLHSKLQHAGFHHLAVTDLFAYPTPETLSLRCRKDA
HDGNRQSITPRQRQQQKRLQQREKRHKGAAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp2 NP_669706.1 HMWP2 nonribosomal peptide synthetase Virulence HPI Protein 0.0 49
irp2 YP_070124.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 49
irp2 YP_002346902.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 49
irp2 YP_853075.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 0.0 49
irp2 NP_993007.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 49
irp2 CAA21390.1 - Virulence HPI Protein 0.0 49
irp2 YP_001006815.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 49
PMI2599 YP_002152317.1 non-ribosomal peptide synthase Not tested Not named Protein 0.0 42