Gene Information

Name : blaA (PAU_02294)
Accession : YP_003041130.1
Strain : Photorhabdus asymbiotica ATCC 43949
Genome accession: NC_012962
Putative virulence/resistance : Resistance
Product : ctx-m type extended-spectrum beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : -
Position : 2605169 - 2606068 bp
Length : 900 bp
Strand : -
Note : Beta-lactamase catalyses the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins

DNA sequence :
TTGCGAGATCCTGATATGAAGCATTCTCCATTGCGGCGTTCATTGTTATTGGCTGGTATTACTCTTCCATTGGTTAACTT
TGCTTTTCCAGCCTGGGCTGGTGCGCTTCCTTCATCACTGTATAAACAACTTGCAGAACTGGAAAACAGCACGAAAGGTC
GTTTGGGAGTGACATTGATCAATACGGCAAATGGTCAGGAGATTCAGTACCGTGGGGATGAGCGTTTTCCTTTCTGTAGT
ACTTTTAAGCTGATAGTTGTTGCAGCAGTGTTACACAAAAGTATGTCCCAGTCAGAGTTGCTGGCAAAACATATCAATTA
TAGTGAAACAGATTTGCTGTCTTACGCTCCTATTGCTCGTAAGCACCTGAATCAAGGTATGAGCATCACGCAATTATGTG
CTGCAACATTGCAATACAGTGACAACACGGCAGTAAATCTGTTGATTAAAGAATTAGGTGGGGTAGAGGCTGTTAACCAT
TTTACCCAAAGCCTTGGTGACCATACATTCCGGCTCGATCGCTGGGAGCCTGATTTGAACAGTGCCATTCCTGATGATCA
CAGAGATACCACAACACCGGCAGCCATGGCGGCCAGTGTGAAGAAAATTGTATTTGGTGAGGTTCTGGCTGAATTGCAAC
GTGACCTGCTGATCGACTGGCTCAAAGGAAATACTACCGGAGATGCCAGTATTCGTGCTGGTGTTCCGACAGGTTGGGTG
GTTGGTGATAAAACTGGCGGCGGTGATTATGGTACCACTAACGATGTTGCCATACTTTGGCCGCCAAAGGGAGCACCTGT
GATTCTGGCAGTTTACTTTACTCAACCTCAGAAAGATGCCGAATCACGCCGTGATGTGCTGGCTTCGGCAACGCGGTTGG
TGATGGAGCATTTGGCTTAA

Protein sequence :
MRDPDMKHSPLRRSLLLAGITLPLVNFAFPAWAGALPSSLYKQLAELENSTKGRLGVTLINTANGQEIQYRGDERFPFCS
TFKLIVVAAVLHKSMSQSELLAKHINYSETDLLSYAPIARKHLNQGMSITQLCAATLQYSDNTAVNLLIKELGGVEAVNH
FTQSLGDHTFRLDRWEPDLNSAIPDDHRDTTTPAAMAASVKKIVFGEVLAELQRDLLIDWLKGNTTGDASIRAGVPTGWV
VGDKTGGGDYGTTNDVAILWPPKGAPVILAVYFTQPQKDAESRRDVLASATRLVMEHLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 3e-66 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JF274247.1.gene1.p01 Protein 3e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY847146.1.gene1.p01 Protein 8e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ211987.1.gene1.p01 Protein 2e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EF418608.1.gene1.p01 Protein 5e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ833651.1.gene1.p01 Protein 1e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ214368.1.gene1.p1 Protein 1e-65 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JF274243.1.gene1.p01 Protein 6e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ214367.1.gene1.p1 Protein 4e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ907381.1.gene1.p01 Protein 2e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JF274246.1.gene1.p01 Protein 2e-65 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EF581888.1.gene1.p01 Protein 4e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF325133.1.gene1.p1 Protein 6e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ214366.1.gene1.p1 Protein 1e-65 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HM755448.1.gene1.p01 Protein 2e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU545409.1.gene1.p1 Protein 4e-65 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF252622.2.gene2.p01 Protein 6e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY847147.1.gene1.p01 Protein 1e-65 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY847144.1.gene1.p01 Protein 6e-66 59
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ214369.1.gene1.p1 Protein 3e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY143430.1.gene1.p01 Protein 1e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY847145.1.gene1.p01 Protein 9e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ398215.1.gene1.p01 Protein 3e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU136031.3.gene1.p3 Protein 7e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ416345.gene.p01 Protein 5e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HM803271.1.gene1.p01 Protein 5e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY156923.1.gene1.p01 Protein 6e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ166709.1.gene1.p01 Protein 3e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ833652.1.gene1.p01 Protein 8e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF252623.2.gene1.p01 Protein 2e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF174129.3.gene9.p01 Protein 5e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY822595.1.gene1.p01 Protein 1e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY847143.1.gene1.p01 Protein 6e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF325134.1.gene1.p1 Protein 2e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY029068.1.gene1.p1 Protein 5e-66 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY033516.1.gene2.p01 Protein 2e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ913565.1.gene1.p01 Protein 4e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JF274242.1.gene1.p01 Protein 4e-65 58
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HM776707.1.gene1.p1 Protein 2e-65 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase GU127598.1.gene1.p1 Protein 2e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase GQ149243.1.gene1.p01 Protein 9e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase X92507.1.gene1.p01 Protein 2e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ005045.gene.p01 Protein 1e-65 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EF374097.1.gene1.p01 Protein 3e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase U95364.1.gene1.p01 Protein 1e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ567481.1.gene1.p01 Protein 3e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase GQ149244.1.gene1.p01 Protein 7e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ102702.1.gene1.p1 Protein 4e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ408762.1.gene1.p1 Protein 9e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ125241.gene.p01 Protein 2e-66 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ416344.1.gene1.p01 Protein 2e-65 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY303807.gene.p01 Protein 9e-63 56
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AB284167.2.gene1.p01 Protein 2e-65 55
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ328639.gene.p01 Protein 1e-61 55
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase Y14156.1.gene1.p01 Protein 1e-64 55
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ557142.gene.p01 Protein 4e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ549244.1.gene1.p01 Protein 1e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY238472.1.gene1.p01 Protein 7e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ885477.1.gene1.p01 Protein 4e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ223685.1.gene1.p01 Protein 1e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EF210159.1.gene1.p01 Protein 2e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY598759.gene.p01 Protein 6e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ663489.gene.p01 Protein 2e-60 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ256091.1.gene1.p1 Protein 3e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AM411407.1.gene1.p01 Protein 1e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY080894.1.gene1.p01 Protein 2e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY649755.1.gene1.p01 Protein 5e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ398214.1.gene1.p01 Protein 2e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU202673.2.gene1.p2 Protein 9e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ061159.1.gene1.p01 Protein 4e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase X92506.gene.p01 Protein 4e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF488377.1.gene1.p1 Protein 2e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU177100.1.gene1.p01 Protein 8e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ810789.1.gene1.p01 Protein 4e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AB177384.1.gene1.p01 Protein 1e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY847148.1.gene1.p01 Protein 8e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF255298.1.gene1.p1 Protein 6e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU402393.1.gene1.p1 Protein 3e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase Y10278.1.gene1.p01 Protein 1e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EF426798.1.gene1.p1 Protein 6e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY515297.1.gene1.p1 Protein 2e-63 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY005110.1.gene1.p1 Protein 2e-60 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EF219142.1.gene1.p01 Protein 2e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY995206.gene.p01 Protein 9e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JF966749.1.gene1.p01 Protein 5e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ268764.2.gene6.p01 Protein 1e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase GQ351346.1.gene1.p01 Protein 8e-64 54
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ815436.1.gene1.p01 Protein 3e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AJ704396.1.gene1.p01 Protein 3e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF305837.gene.p01 Protein 2e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JN227085.1.gene1.p01 Protein 4e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ873739.1.gene1.p01 Protein 3e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY267213.1.gene1.p01 Protein 3e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY292654.1.gene1.p1 Protein 1e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AB205197.1.gene1.p01 Protein 8e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY750914.gene.p01 Protein 6e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AM982522.2.gene1.p01 Protein 2e-64 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY157676.1.gene1.p01 Protein 1e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ971899.1.gene1.p1 Protein 2e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase GQ870432.1.gene1.p1 Protein 2e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY954516.1.gene1.p1 Protein 5e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF518567.2.gene4.p01 Protein 2e-63 53
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HM167760.1.gene1.p01 Protein 2e-63 52
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF189721.1.gene1.p01 Protein 4e-63 52
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase DQ023162.1.gene1.p1 Protein 1e-62 52
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF395881.gene.p01 Protein 4e-53 50
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU729727.1.gene1.p1 Protein 2e-53 50
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase GQ140348.1.gene1.p01 Protein 6e-53 50
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase FJ234412.1.gene1.p01 Protein 5e-53 50
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase EU555534.1.gene1.p01 Protein 4e-53 49
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AY034847.1.gene1.p01 Protein 4e-53 49
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HM066995.1.gene1.p01 Protein 1e-52 49
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF297554.1.gene1.p1 Protein 4e-53 49
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase HQ641421.1.gene1.p01 Protein 5e-53 48
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase U50278.1.gene2.p01 Protein 5e-47 47
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF275256.gene.p01 Protein 2e-47 43
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase Z28968.gene.p01 Protein 5e-47 41
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase JF949916.1.gene1.p01 Protein 3e-41 41
blaA YP_003041130.1 ctx-m type extended-spectrum beta-lactamase AF367983.gene.p01 Protein 3e-42 41