Gene Information

Name : ribD (ECBD_3247)
Accession : YP_003037432.1
Strain : Escherichia coli Escherichia coli BL21-Gold(DE3)pLysS AG
Genome accession: NC_012947
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 3.5.4.26
Position : 3382425 - 3383528 bp
Length : 1104 bp
Strand : -
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
GTGCAGGACGAGTATTACATGGCGCGGGCGCTAAAGCTGGCGCAACGAGGACGTTTTACCACGCATCCCAACCCGAATGT
CGGGTGCGTCATTGTCAAAGATGGCGAAATTGTCGGTGAAGGTTACCACCAACGTGCGGGTGAACCACATGCCGAAGTAC
ACGCGTTGCGTATGGCGGGTGAAAAAGCCAAAGGTGCGACCGCCTATGTCACACTCGAACCCTGTAGCCATCATGGTCGT
ACGCCACCGTGCTGTGACGCACTCATCGCCGCTGGCGTAGCGCGCGTGGTTGCCTCGATGCAAGATCCTAACCCGCAGGT
CGCTGGGCGTGGACTTTACCGTCTGCAACAGGCTGGCATTGACGTCAGCCACGGCCTGATGATGAGTGAAGCCGAGCAAT
TGAATAAAGGCTTTCTCAAGCGGATGCGCACCGGCTTTCCTTATATTCAGTTAAAACTTGGCGCATCGCTTGATGGTCGC
ACGGCGATGGCGAGCGGCGAAAGCCAGTGGATCACTTCGCCCCAGGCGCGGCGTGATGTACAACTACTGCGCGCGCAAAG
TCATGCCATTTTAACCAGCAGCGCCACGGTGCTGGCGGATGATCCTGCCTTAACGGTGCGTTGGTCTGAACTGGATGAAC
AAACTCAGGCGCTCTATCCGCAACAAAATCTCCGTCAGCCGATACGTATTGTGATTGATAGCCAAAATCGCGTGACGCCG
GTACATCGCATTGTGCAGCAGCCCGGCGAAACCTGGTTCGCGCGTACGCAGGAAGATTCTCGTGAGTGGCCGGAAACGGT
GCGTACCTTGCTGATTCCAGCGCATAAAGGTCATCTGGATCTGGTTGTACTGATGATGCAACTGGGTAAACAGCAAATTA
ACAGCATCTGGGTGGAAGCGGGGCCAACGCTCGCTGGCGCATTGCTGCAGGCGGGTTTAGTCGATGAGCTGATTGTCTAT
ATCGCACCTAAACTATTAGGCAGCGACGCCCGTGGATTATGCTCGCTGCCAGGGCTTGAGAAATTAGCCGACGCCCCCCA
ATTTAAATTCAAAGAGATACGTCATGTAGGCCCGGATGTTTGCCTGCATTTAGTAGGTGCATGA

Protein sequence :
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVASMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQLLRAQSHAILTSSATVLADDPALTVRWSELDEQTQALYPQQNLRQPIRIVIDSQNRVTP
VHRIVQQPGETWFARTQEDSREWPETVRTLLIPAHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVY
IAPKLLGSDARGLCSLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 7e-65 47
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 7e-65 47