Gene Information

Name : ECBD_3091 (ECBD_3091)
Accession : YP_003037282.1
Strain : Escherichia coli Escherichia coli BL21-Gold(DE3)pLysS AG
Genome accession: NC_012947
Putative virulence/resistance : Virulence
Product : CusR family transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3228259 - 3228942 bp
Length : 684 bp
Strand : +
Note : response regulator in two-component regulatory system with CusS; regulates the copper efflux system

DNA sequence : 
ATGAAACTGTTGATTGTCGAAGATGAAAAGAAAACCGGAGAATACTTGACCAAAGGGTTAACCGAAGCCGGTTTTGTGGT
CGATTTGGCCGACAACGGGCTGAATGGCTACCATCTGGCGATGACCGGTGATTATGATCTGATAATCCTCGATATTATGC
TGCCGGACGTGAACGGCTGGGATATCGTGCGCATGTTACGCTCCGCCAATAAAGGGATGCCGATTCTGTTGCTTACCGCG
CTTGGCACCATTGAACATCGCGTCAAGGGGCTGGAGTTGGGGGCAGATGACTACCTGATGAAACCATTCGCTTTTGCTGA
ACTGCTGGCGCGGGTGCGCACTCTCCTGCGGCGCGGGGCGGCGGTAATTATCGAAAGTCAGTTTCAGGTTGCCGACCTGA
TGGTCGATCTCGTCAGCCGCAAAGTCACCCGCAGCGGCACGCGCATCACTCTGACCAGTAAAGAGTTTACTCTGCTGGAG
TTTTTTCTCCGCCATCAGGGCGAAGTGCTGCCCCGCTCGCTTATCGCCTCGCAGGTGTGGGACATGAATTTCGACAGCGA
CACTAACGCCATTGATGTGGCGGTGAAGCGGCTACGCGGCAAAATCGACAACGACTTTGAGCCGAAGCTGATTCAGACCG
TGCGCGGCGTGGGCTATATGCTTGAGGTGCCGGATGGTCAGTAA

Protein sequence : 
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTA
LGTIEHRVKGLELGADDYLMKPFAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 6e-56 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-56 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0111 Protein 1e-103 99
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0347 Protein 5e-87 82
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0638 Protein 3e-63 62
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0083 Protein 3e-70 61
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0308 Protein 1e-63 60
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0197 Protein 2e-63 59
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator BAC0125 Protein 1e-63 56
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator AE000516.2.gene3505. Protein 6e-28 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator VFG0596 Protein 2e-56 52
ECBD_3091 YP_003037282.1 CusR family transcriptional regulator VFG1390 Protein 3e-43 43