Gene Information

Name : rph (TBMG_02638)
Accession : YP_003032613.1
Strain : Mycobacterium tuberculosis KZN 1435
Genome accession: NC_012943
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : -
Position : 2904813 - 2905592 bp
Length : 780 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
GTGTCCAAGCGAGAAGACGGCCGGCTCGACCACGAGCTTCGCCCGGTGATCATCACCCGCGGTTTCACCGAAAACCCGGC
GGGATCGGTGCTCATCGAATTCGGTCACACCAAGGTCCTGTGCACCGCCAGCGTCACCGAAGGGGTGCCCCGGTGGCGTA
AAGCAACCGGTCTGGGGTGGCTCACCGCGGAGTACGCCATGCTGCCGTCGGCCACCCACAGCCGCTCTGATCGCGAGTCG
GTGAGAGGCAGGCTTAGCGGGCGTACTCAGGAAATCAGTCGGCTCATCGGCCGGTCGCTGCGCGCATGCATCGACCTGGC
GGCGCTGGGGGAGAACACGATCGCTATCGATTGTGATGTGTTGCAGGCCGATGGTGGCACTCGAACCGCGGCCATCACCG
GCGCCTACGTGGCATTGGCCGACGCAGTGACCTACTTGTCGGCGGCGGGTAAGTTGTCCGACCCCAGGCCATTGTCGTGT
GCCATCGCCGCGGTCAGCGTCGGTGTTGTCGACGGCAGGATCCGGGTGGATCTGCCCTACGAGGAAGATTCGCGCGCCGA
GGTCGACATGAACGTCGTCGCTACCGACACCGGAACCCTGGTAGAGATTCAGGGCACCGGCGAAGGCGCGACGTTCGCAC
GTTCGACACTGGATAAGCTGCTGGACATGGCACTGGGCGCCTGCGACACGTTGTTTGCCGCACAACGCGACGCGTTGGCG
CTGCCGTATCCGGGTGTGCTGCCGCAGGGACCGCCACCGCCGAAGGCGTTTGGCACCTGA

Protein sequence :
MSKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKATGLGWLTAEYAMLPSATHSRSDRES
VRGRLSGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAITGAYVALADAVTYLSAAGKLSDPRPLSC
AIAAVSVGVVDGRIRVDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFAAQRDALA
LPYPGVLPQGPPPPKAFGT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 2e-68 65