Gene Information

Name : ureA (TBMG_02146)
Accession : YP_003032109.1
Strain : Mycobacterium tuberculosis KZN 1435
Genome accession: NC_012943
Putative virulence/resistance : Unknown
Product : urease subunit gamma
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0831
EC number : -
Position : 2325281 - 2325601 bp
Length : 321 bp
Strand : -
Note : UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter

DNA sequence :
GTGGCAGGATCGCAGAGCATGCGCCTGACGCCGCACGAACAGGAGCGTTTGCTGTTGTCCTACGCCGCCGAGTTGGCCCG
CCGGCGTCGGGCCCGCGGCCTGCGCCTCAATCATCCGGAAGCCATCGCGGTGATCGCCGACCACATCCTGGAAGGCGCGC
GTGACGGCCGCACCGTCGCAGAGTTGATGGCATCCGGGCGTGAGGTGCTCGGCCGTGACGATGTGATGGAGGGAGTGCCG
GAGATGCTCGCCGAGGTACAGGTGGAGGCGACGTTTCCGGACGGCACCAAGTTGGTCACCGTGCATCAGCCGATCGCATG
A

Protein sequence :
MAGSQSMRLTPHEQERLLLSYAAELARRRRARGLRLNHPEAIAVIADHILEGARDGRTVAELMASGREVLGRDDVMEGVP
EMLAEVQVEATFPDGTKLVTVHQPIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureA YP_005682176.1 urease subunit gamma Not tested PiCp 7 Protein 8e-22 68
ureA YP_005684268.1 urease subunit gamma Not tested PiCp 7 Protein 8e-22 68
ureA YP_003784327.1 urease subunit gamma Not tested PiCp 7 Protein 8e-22 68
ureA YP_005686360.1 urease subunit gamma Not tested PiCp 7 Protein 8e-22 68